Computational Biology

Distance Measures for Tumor Evolutionary Trees

We introduce distance metrics on tumor evolutionary trees to use for benchmmarking inference methods or clustering trees.

Parameter, Noise, and Tree Topology Effects in Tumor Phylogeny Inference

An extended journal version of our 2018 BIBM paper. We examine how aspects of sequencing data and patterns of tumor evolution affect phylogeny inference.

Examining Tumor Phylogeny Inference in Noisy Sequencing Data

We explore when and how well tumor evolutionary histories can be inferred from multi-sample bulk sequencing data.