<article>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#article09_11_03_1450211</id>
	<title>Scientists Build a Smarter Rat</title>
	<author>timothy</author>
	<datestamp>1257261720000</datestamp>
	<htmltext>destinyland writes <i>"Scientists have engineered a more intelligent rat, with <a href="http://www.hplusmagazine.com/articles/neuro/making-smarter-rat">three times the memory length of today's smartest rats</a>. Reseachers bred transgenic over-expression of the NR2B gene, which increased communication between the rat's memory synapses. Activating a crucial brain receptor for just a fraction of a second longer produces a dramatic effect on memory, as proven by the rat's longer memories of the path through a maze."</i></htmltext>
<tokenext>destinyland writes " Scientists have engineered a more intelligent rat , with three times the memory length of today 's smartest rats .
Reseachers bred transgenic over-expression of the NR2B gene , which increased communication between the rat 's memory synapses .
Activating a crucial brain receptor for just a fraction of a second longer produces a dramatic effect on memory , as proven by the rat 's longer memories of the path through a maze .
"</tokentext>
<sentencetext>destinyland writes "Scientists have engineered a more intelligent rat, with three times the memory length of today's smartest rats.
Reseachers bred transgenic over-expression of the NR2B gene, which increased communication between the rat's memory synapses.
Activating a crucial brain receptor for just a fraction of a second longer produces a dramatic effect on memory, as proven by the rat's longer memories of the path through a maze.
"</sentencetext>
</article>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29967994</id>
	<title>Re:We already knew it worked for mice</title>
	<author>ae1294</author>
	<datestamp>1257241920000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><div class="quote"><p>It's a possibility, but I don't think so. The receptors don't use a lot of energy. The baseline cost of maintaining the neurons won't change. So the main incremental cost will be the pump costs for repolarizing after action potentials. But it doesn't seem likely that overall firing is massively increased, or they'd probably be seizing.</p></div><p>When I read this post the voice in my head was that of Geordi La Forge.</p></div>
	</htmltext>
<tokenext>It 's a possibility , but I do n't think so .
The receptors do n't use a lot of energy .
The baseline cost of maintaining the neurons wo n't change .
So the main incremental cost will be the pump costs for repolarizing after action potentials .
But it does n't seem likely that overall firing is massively increased , or they 'd probably be seizing.When I read this post the voice in my head was that of Geordi La Forge .</tokentext>
<sentencetext>It's a possibility, but I don't think so.
The receptors don't use a lot of energy.
The baseline cost of maintaining the neurons won't change.
So the main incremental cost will be the pump costs for repolarizing after action potentials.
But it doesn't seem likely that overall firing is massively increased, or they'd probably be seizing.When I read this post the voice in my head was that of Geordi La Forge.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964302</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963778</id>
	<title>The rats' name is not 'Algernon', or is it?</title>
	<author>treczoks</author>
	<datestamp>1257265620000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>5</modscore>
	<htmltext><p>"Flowers for Algernon" was the first association that popped up from the depths of my mind...</p></htmltext>
<tokenext>" Flowers for Algernon " was the first association that popped up from the depths of my mind.. .</tokentext>
<sentencetext>"Flowers for Algernon" was the first association that popped up from the depths of my mind...</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964762</id>
	<title>That's funny</title>
	<author>lymond01</author>
	<datestamp>1257269640000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>One of my scientist friends was on this team.  We'd always go to the renaissance faires together -- she was always big into the art booths, always liked those renaissance period painters.  Her work was on turtles though...</p></htmltext>
<tokenext>One of my scientist friends was on this team .
We 'd always go to the renaissance faires together -- she was always big into the art booths , always liked those renaissance period painters .
Her work was on turtles though.. .</tokentext>
<sentencetext>One of my scientist friends was on this team.
We'd always go to the renaissance faires together -- she was always big into the art booths, always liked those renaissance period painters.
Her work was on turtles though...</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29967738</id>
	<title>Re:We already knew it worked for mice</title>
	<author>Bruce Perens</author>
	<datestamp>1257240780000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>2</modscore>
	<htmltext><blockquote><div><p>if intelligence can be increased by something so simple as an increase in the expression of a single NMDA receptor subunit, why hasn't it already happened?</p></div></blockquote><p>It has, or you wouldn't be here<nobr> <wbr></nobr>:-)</p></div>
	</htmltext>
<tokenext>if intelligence can be increased by something so simple as an increase in the expression of a single NMDA receptor subunit , why has n't it already happened ? It has , or you would n't be here : - )</tokentext>
<sentencetext>if intelligence can be increased by something so simple as an increase in the expression of a single NMDA receptor subunit, why hasn't it already happened?It has, or you wouldn't be here :-)
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29974938</id>
	<title>Re:The secret...</title>
	<author>Chris Burke</author>
	<datestamp>1257022200000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><blockquote><div><p>science could bread more intelligent rats</p><p>Mmmmmm... breaded rats.</p></div></blockquote><p>You can really taste the intelligence!</p></div>
	</htmltext>
<tokenext>science could bread more intelligent ratsMmmmmm... breaded rats.You can really taste the intelligence !</tokentext>
<sentencetext>science could bread more intelligent ratsMmmmmm... breaded rats.You can really taste the intelligence!
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964092</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29965260</id>
	<title>Re:The rats' name is not 'Algernon', or is it?</title>
	<author>Gilmoure</author>
	<datestamp>1257271740000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>Elenor?</p></htmltext>
<tokenext>Elenor ?</tokentext>
<sentencetext>Elenor?</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963778</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29965076</id>
	<title>Re:Spooky</title>
	<author>foobsr</author>
	<datestamp>1257271020000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><i>While I know that this sort of research is ultimately aimed at improving human life,<nobr> <wbr></nobr>..</i>
<br> <br>
Like in "The Pentagon (whoever, YMMV) sponsored a research program to evaluate the use of artificially improved mammals in the fight against terrorism"?
<br> <br>
CC.</htmltext>
<tokenext>While I know that this sort of research is ultimately aimed at improving human life , . . Like in " The Pentagon ( whoever , YMMV ) sponsored a research program to evaluate the use of artificially improved mammals in the fight against terrorism " ?
CC .</tokentext>
<sentencetext>While I know that this sort of research is ultimately aimed at improving human life, ..
 
Like in "The Pentagon (whoever, YMMV) sponsored a research program to evaluate the use of artificially improved mammals in the fight against terrorism"?
CC.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963762</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964092</id>
	<title>Re:The secret...</title>
	<author>Anonymous</author>
	<datestamp>1257266880000</datestamp>
	<modclass>Funny</modclass>
	<modscore>2</modscore>
	<htmltext><p><div class="quote"><p>science could bread more intelligent rats</p></div><p>Mmmmmm... breaded rats.</p></div>
	</htmltext>
<tokenext>science could bread more intelligent ratsMmmmmm... breaded rats .</tokentext>
<sentencetext>science could bread more intelligent ratsMmmmmm... breaded rats.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963760</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964506</id>
	<title>Re:We already knew it worked for mice</title>
	<author>topcoder</author>
	<datestamp>1257268680000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><div class="quote"><p>Presumably, there is some kind of downside that balances that selective advantage. Are there other behaviors for which the rat is impaired?</p></div><p>Rats now become socially awkward, start becoming interested in programming and videogames, so losing any chance to succesfully reproduce.</p></div>
	</htmltext>
<tokenext>Presumably , there is some kind of downside that balances that selective advantage .
Are there other behaviors for which the rat is impaired ? Rats now become socially awkward , start becoming interested in programming and videogames , so losing any chance to succesfully reproduce .</tokentext>
<sentencetext>Presumably, there is some kind of downside that balances that selective advantage.
Are there other behaviors for which the rat is impaired?Rats now become socially awkward, start becoming interested in programming and videogames, so losing any chance to succesfully reproduce.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963884</id>
	<title>Faster Memory?</title>
	<author>Xebikr</author>
	<datestamp>1257265980000</datestamp>
	<modclass>Funny</modclass>
	<modscore>4</modscore>
	<htmltext><blockquote><div><p> Activating a crucial brain receptor for just a fraction of a second longer produces a dramatic effect on memory</p></div></blockquote><p>
So they overclocked the rats? Cool!</p></div>
	</htmltext>
<tokenext>Activating a crucial brain receptor for just a fraction of a second longer produces a dramatic effect on memory So they overclocked the rats ?
Cool !</tokentext>
<sentencetext> Activating a crucial brain receptor for just a fraction of a second longer produces a dramatic effect on memory
So they overclocked the rats?
Cool!
	</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964014</id>
	<title>Re:NIMH</title>
	<author>Anonymous</author>
	<datestamp>1257266640000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext>Props for using the F.</htmltext>
<tokenext>Props for using the F .</tokentext>
<sentencetext>Props for using the F.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963746</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964392</id>
	<title>Re:We already knew it worked for mice</title>
	<author>RJBeery</author>
	<datestamp>1257268140000</datestamp>
	<modclass>Funny</modclass>
	<modscore>2</modscore>
	<htmltext><p><div class="quote"><p>Nevertheless, it raises an interesting question: if intelligence can be increased by something so simple as an increase in the expression of a single NMDA receptor subunit, why hasn't it already happened?</p></div><p>It HAS happened, but those affected (rats included) simply can't get laid to propagate the phenomenon...</p></div>
	</htmltext>
<tokenext>Nevertheless , it raises an interesting question : if intelligence can be increased by something so simple as an increase in the expression of a single NMDA receptor subunit , why has n't it already happened ? It HAS happened , but those affected ( rats included ) simply ca n't get laid to propagate the phenomenon.. .</tokentext>
<sentencetext>Nevertheless, it raises an interesting question: if intelligence can be increased by something so simple as an increase in the expression of a single NMDA receptor subunit, why hasn't it already happened?It HAS happened, but those affected (rats included) simply can't get laid to propagate the phenomenon...
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964636</id>
	<title>I for one ...</title>
	<author>nevermore94</author>
	<datestamp>1257269100000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>can't remember how this meme should go.</htmltext>
<tokenext>ca n't remember how this meme should go .</tokentext>
<sentencetext>can't remember how this meme should go.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964082</id>
	<title>Re:We already knew it worked for mice</title>
	<author>John Hasler</author>
	<datestamp>1257266820000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>4</modscore>
	<htmltext><p>&gt; Presumably, there is some kind of downside that balances that selective<br>&gt; advantage.</p><p>Higher energy requirements would be a good bet.</p></htmltext>
<tokenext>&gt; Presumably , there is some kind of downside that balances that selective &gt; advantage.Higher energy requirements would be a good bet .</tokentext>
<sentencetext>&gt; Presumably, there is some kind of downside that balances that selective&gt; advantage.Higher energy requirements would be a good bet.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</id>
	<title>We already knew it worked for mice</title>
	<author>tgibbs</author>
	<datestamp>1257266340000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>5</modscore>
	<htmltext><p>Kind of old news; the first report that NR2B overexpression improves rodent performance in some behavioral tests of learning and memory was <a href="ttp:wwwncbinlmnihgovpubmed10485705itoolEntrezSystem2PEntrezPubmedPubmedResultsPanelPubmedRVDocSumordinalpos6" title="ttp">was published in 1999</a> [ttp]. The nice thing here is that the investigators now have it working in the rat, which is a more difficult animal for transgenic studies, and a better one for behavioral work and electrophysiology.</p><p>Nevertheless, it raises an interesting question: if intelligence can be increased by something so simple as an increase in the expression of a single NMDA receptor subunit, why hasn't it already happened? Presumably, there is a selective advantage to improved learning and memory. Presumably, there is some kind of downside that balances that selective advantage. Are there other behaviors for which the rat is impaired?</p></htmltext>
<tokenext>Kind of old news ; the first report that NR2B overexpression improves rodent performance in some behavioral tests of learning and memory was was published in 1999 [ ttp ] .
The nice thing here is that the investigators now have it working in the rat , which is a more difficult animal for transgenic studies , and a better one for behavioral work and electrophysiology.Nevertheless , it raises an interesting question : if intelligence can be increased by something so simple as an increase in the expression of a single NMDA receptor subunit , why has n't it already happened ?
Presumably , there is a selective advantage to improved learning and memory .
Presumably , there is some kind of downside that balances that selective advantage .
Are there other behaviors for which the rat is impaired ?</tokentext>
<sentencetext>Kind of old news; the first report that NR2B overexpression improves rodent performance in some behavioral tests of learning and memory was was published in 1999 [ttp].
The nice thing here is that the investigators now have it working in the rat, which is a more difficult animal for transgenic studies, and a better one for behavioral work and electrophysiology.Nevertheless, it raises an interesting question: if intelligence can be increased by something so simple as an increase in the expression of a single NMDA receptor subunit, why hasn't it already happened?
Presumably, there is a selective advantage to improved learning and memory.
Presumably, there is some kind of downside that balances that selective advantage.
Are there other behaviors for which the rat is impaired?</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964232</id>
	<title>Other Rodent Upgrade Experiments</title>
	<author>Anonymous</author>
	<datestamp>1257267420000</datestamp>
	<modclass>Interestin</modclass>
	<modscore>5</modscore>
	<htmltext>About eight years ago I read about a line of experiments that measurably increased rodents' performance in a set of memory and learning tasks. I believe the genetic change involved the NMDA receptor, but a quick search doesn't turn up an obvious link to that.<br> <br>
There was <a href="http://scienceblogs.com/notrocketscience/2009/09/gene\_therapy\_gives\_full\_colour\_vision\_to\_colour-blind\_monkey.php" title="scienceblogs.com">a report this September</a> [scienceblogs.com] that gene therapy had been used to grant "full" color vision to colorblind monkeys, following on an earlier experiment that did the same thing to rodents. That is, the rodents were given three-color vision where they normally have two color receptor types. (Would that make them transrodents?) Apparently, the brain automatically adapts to having a new receptor type installed in the retina! And the same technique could be used on humans to grant us a fourth receptor type, maybe a UV receptor gotten from parrots or something. I'd volunteer to have this done to one eye. (The first comment on <a href="http://ecodevoevo.blogspot.com/2009/09/evolutionary-significance-of-color.html" title="blogspot.com">this article</a> [blogspot.com] presents a dissenting view that just because the monkeys were able to distinguish colors in greater detail than before, that shouldn't be taken as proof that they "have full color vision". All the more reason to try it in a human!)<br> <br>
The rodents could be in combination with cyborg cats though, as seen in <a href="http://www.futurefeeder.com/2005/06/extracting-video-from-the-brain/" title="futurefeeder.com">this 1995 report</a> [futurefeeder.com] of recognizable images read directly from a cat's visual cortex.</htmltext>
<tokenext>About eight years ago I read about a line of experiments that measurably increased rodents ' performance in a set of memory and learning tasks .
I believe the genetic change involved the NMDA receptor , but a quick search does n't turn up an obvious link to that .
There was a report this September [ scienceblogs.com ] that gene therapy had been used to grant " full " color vision to colorblind monkeys , following on an earlier experiment that did the same thing to rodents .
That is , the rodents were given three-color vision where they normally have two color receptor types .
( Would that make them transrodents ?
) Apparently , the brain automatically adapts to having a new receptor type installed in the retina !
And the same technique could be used on humans to grant us a fourth receptor type , maybe a UV receptor gotten from parrots or something .
I 'd volunteer to have this done to one eye .
( The first comment on this article [ blogspot.com ] presents a dissenting view that just because the monkeys were able to distinguish colors in greater detail than before , that should n't be taken as proof that they " have full color vision " .
All the more reason to try it in a human !
) The rodents could be in combination with cyborg cats though , as seen in this 1995 report [ futurefeeder.com ] of recognizable images read directly from a cat 's visual cortex .</tokentext>
<sentencetext>About eight years ago I read about a line of experiments that measurably increased rodents' performance in a set of memory and learning tasks.
I believe the genetic change involved the NMDA receptor, but a quick search doesn't turn up an obvious link to that.
There was a report this September [scienceblogs.com] that gene therapy had been used to grant "full" color vision to colorblind monkeys, following on an earlier experiment that did the same thing to rodents.
That is, the rodents were given three-color vision where they normally have two color receptor types.
(Would that make them transrodents?
) Apparently, the brain automatically adapts to having a new receptor type installed in the retina!
And the same technique could be used on humans to grant us a fourth receptor type, maybe a UV receptor gotten from parrots or something.
I'd volunteer to have this done to one eye.
(The first comment on this article [blogspot.com] presents a dissenting view that just because the monkeys were able to distinguish colors in greater detail than before, that shouldn't be taken as proof that they "have full color vision".
All the more reason to try it in a human!
) 
The rodents could be in combination with cyborg cats though, as seen in this 1995 report [futurefeeder.com] of recognizable images read directly from a cat's visual cortex.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29966608</id>
	<title>Re:We already knew it worked for mice</title>
	<author>Anonymous</author>
	<datestamp>1257278040000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>Selection pressure works in the negative. Even if it adds a benefit, the individual critters without it would have to fail to breed. As long as the current is sufficient, we'll get more of the current.</p></htmltext>
<tokenext>Selection pressure works in the negative .
Even if it adds a benefit , the individual critters without it would have to fail to breed .
As long as the current is sufficient , we 'll get more of the current .</tokentext>
<sentencetext>Selection pressure works in the negative.
Even if it adds a benefit, the individual critters without it would have to fail to breed.
As long as the current is sufficient, we'll get more of the current.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964324</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964694</id>
	<title>Re:Faster Memory?</title>
	<author>Anonymous</author>
	<datestamp>1257269340000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>But will it be a reason good enough for enthusiast end-users to upgrade?</p></htmltext>
<tokenext>But will it be a reason good enough for enthusiast end-users to upgrade ?</tokentext>
<sentencetext>But will it be a reason good enough for enthusiast end-users to upgrade?</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963884</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29967142</id>
	<title>Re:Spooky</title>
	<author>Anonymous</author>
	<datestamp>1257281220000</datestamp>
	<modclass>Funny</modclass>
	<modscore>1</modscore>
	<htmltext>In related news, Infosys has announced the availability of new<nobr> <wbr></nobr>.NET programmers that are cheaper replacements for Indian programmers. The company would not discuss rumors it was replacing cubicles with small wire cages, however it has ordered tiny tiny keyboards and cursor-positioning device it referred to as 'not mice. Definitely not mice. No, we are not using mice.'</htmltext>
<tokenext>In related news , Infosys has announced the availability of new .NET programmers that are cheaper replacements for Indian programmers .
The company would not discuss rumors it was replacing cubicles with small wire cages , however it has ordered tiny tiny keyboards and cursor-positioning device it referred to as 'not mice .
Definitely not mice .
No , we are not using mice .
'</tokentext>
<sentencetext>In related news, Infosys has announced the availability of new .NET programmers that are cheaper replacements for Indian programmers.
The company would not discuss rumors it was replacing cubicles with small wire cages, however it has ordered tiny tiny keyboards and cursor-positioning device it referred to as 'not mice.
Definitely not mice.
No, we are not using mice.
'</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963762</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964554</id>
	<title>Re:at what cost?</title>
	<author>wurp</author>
	<datestamp>1257268800000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>Bravo!</p><p>Well done, sir.</p></htmltext>
<tokenext>Bravo ! Well done , sir .</tokentext>
<sentencetext>Bravo!Well done, sir.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964080</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964276</id>
	<title>Re:We already knew it worked for mice</title>
	<author>steelfood</author>
	<datestamp>1257267600000</datestamp>
	<modclass>Funny</modclass>
	<modscore>2</modscore>
	<htmltext><p>To answer this question, I reference Idiocracy.</p></htmltext>
<tokenext>To answer this question , I reference Idiocracy .</tokentext>
<sentencetext>To answer this question, I reference Idiocracy.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29983096</id>
	<title>Next Step</title>
	<author>Anonymous</author>
	<datestamp>1257019440000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>Release it to the nature.</p></htmltext>
<tokenext>Release it to the nature .</tokentext>
<sentencetext>Release it to the nature.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964116</id>
	<title>TL;DR</title>
	<author>Anonymous</author>
	<datestamp>1257267000000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>We need like... 4 page reviews, maximum.</p></htmltext>
<tokenext>We need like... 4 page reviews , maximum .</tokentext>
<sentencetext>We need like... 4 page reviews, maximum.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29991484</id>
	<title>Re:We already knew it worked for mice</title>
	<author>bar-agent</author>
	<datestamp>1257015900000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>My guess is they'd need more sleep or else suffer confusion and indecision.</p></htmltext>
<tokenext>My guess is they 'd need more sleep or else suffer confusion and indecision .</tokentext>
<sentencetext>My guess is they'd need more sleep or else suffer confusion and indecision.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964082</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964358</id>
	<title>Corrected link</title>
	<author>tgibbs</author>
	<datestamp>1257267960000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><a href="http://www.ncbi.nlm.nih.gov/pubmed/10485705?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed\_ResultsPanel.Pubmed\_RVDocSum&amp;ordinalpos=18" title="nih.gov">corrected link</a> [nih.gov]</p></htmltext>
<tokenext>corrected link [ nih.gov ]</tokentext>
<sentencetext>corrected link [nih.gov]</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964470</id>
	<title>Tomorrow the Rat</title>
	<author>Anonymous</author>
	<datestamp>1257268440000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>Time to call for Doomwatch</p><p>http://www.doomwatch.org/season1tomorrowtheratreview.html</p></htmltext>
<tokenext>Time to call for Doomwatchhttp : //www.doomwatch.org/season1tomorrowtheratreview.html</tokentext>
<sentencetext>Time to call for Doomwatchhttp://www.doomwatch.org/season1tomorrowtheratreview.html</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964728</id>
	<title>Just what we need</title>
	<author>Hognoxious</author>
	<datestamp>1257269460000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>Just what we need, smarter rats.  Now I'll just have to build a better mousetrap.</htmltext>
<tokenext>Just what we need , smarter rats .
Now I 'll just have to build a better mousetrap .</tokentext>
<sentencetext>Just what we need, smarter rats.
Now I'll just have to build a better mousetrap.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963752</id>
	<title>Oh my!</title>
	<author>jockeys</author>
	<datestamp>1257265560000</datestamp>
	<modclass>Redundant</modclass>
	<modscore>-1</modscore>
	<htmltext>We need to alert Mrs. Frisby at once!</htmltext>
<tokenext>We need to alert Mrs. Frisby at once !</tokentext>
<sentencetext>We need to alert Mrs. Frisby at once!</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29965560</id>
	<title>False alarm  folks</title>
	<author>Anonymous</author>
	<datestamp>1257273060000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>They forgot to take into account the lead scientist had alzheimers and hence the memory span of a goldfish.</p></htmltext>
<tokenext>They forgot to take into account the lead scientist had alzheimers and hence the memory span of a goldfish .</tokentext>
<sentencetext>They forgot to take into account the lead scientist had alzheimers and hence the memory span of a goldfish.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29965074</id>
	<title>Obligatory</title>
	<author>LuxMaker</author>
	<datestamp>1257271020000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>I for one welcome our new rat overlords.</htmltext>
<tokenext>I for one welcome our new rat overlords .</tokentext>
<sentencetext>I for one welcome our new rat overlords.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964918</id>
	<title>Re:at what cost?</title>
	<author>SteveFoerster</author>
	<datestamp>1257270240000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>That was the best Slashdot comment I have ever read.</p></htmltext>
<tokenext>That was the best Slashdot comment I have ever read .</tokentext>
<sentencetext>That was the best Slashdot comment I have ever read.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964080</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29971002</id>
	<title>Re:We already knew it worked for mice</title>
	<author>Anonymous</author>
	<datestamp>1257252600000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>&gt; Are there other behaviors for which the rat is impaired?</p><p>Giving two thumbs up on a job well done.</p></htmltext>
<tokenext>&gt; Are there other behaviors for which the rat is impaired ? Giving two thumbs up on a job well done .</tokentext>
<sentencetext>&gt; Are there other behaviors for which the rat is impaired?Giving two thumbs up on a job well done.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29974186</id>
	<title>Re:The rats' name is not 'Algernon', or is it?</title>
	<author>chuckymonkey</author>
	<datestamp>1257274140000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>That was a heart rending book, and it spoke to one of my most personal primal fears.  Living with a reduced mental capacity and knowing it would be a living hell for me.</htmltext>
<tokenext>That was a heart rending book , and it spoke to one of my most personal primal fears .
Living with a reduced mental capacity and knowing it would be a living hell for me .</tokentext>
<sentencetext>That was a heart rending book, and it spoke to one of my most personal primal fears.
Living with a reduced mental capacity and knowing it would be a living hell for me.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963778</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964218</id>
	<title>Re:I for one</title>
	<author>istartedi</author>
	<datestamp>1257267360000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p> <em>welcome our new Rat Bastard overlords!
</em> </p><p>New?</p></htmltext>
<tokenext>welcome our new Rat Bastard overlords !
New ?</tokentext>
<sentencetext> welcome our new Rat Bastard overlords!
New?</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963726</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963814</id>
	<title>The world needs this....</title>
	<author>gilesjuk</author>
	<datestamp>1257265800000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>2</modscore>
	<htmltext><p>We need this about as much as we need a much stronger more deadly flu virus.</p><p>When rats are vermin and carry disease, why make them even better a survival? or are they scientists thinking that if they get clever enough they'll start writing software for a living?</p></htmltext>
<tokenext>We need this about as much as we need a much stronger more deadly flu virus.When rats are vermin and carry disease , why make them even better a survival ?
or are they scientists thinking that if they get clever enough they 'll start writing software for a living ?</tokentext>
<sentencetext>We need this about as much as we need a much stronger more deadly flu virus.When rats are vermin and carry disease, why make them even better a survival?
or are they scientists thinking that if they get clever enough they'll start writing software for a living?</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29971024</id>
	<title>Re:We already knew it worked for mice</title>
	<author>Anonymous</author>
	<datestamp>1257252660000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>You are making the mistake of assuming that evolution always gives us desirable traits.  Evolution is really not intelligent.  It's just making random code changes, for our species we get a coherent (expressible) mutation about once in every 8 generations.</p><p>Evolution is only about 1 thing, breeding.  If an individual has more babies than another individual then his genes are selected for.</p><p>Three possibilities that I can come up with:</p><p>1. <em>Random</em> mutations haven't yet given our species overproduction of this receptor protein.  I'm going out on a limb here and assuming that they got over-expression by repeating the gene sequence. Tandem duplications usually happen in specific places in the genome where the DNA replication enzymes get "stuck" when replicating the parent strand, causing repeats.</p><p>2. Over-expression of this protein doesn't give any kind of fitness (for reproduction) advantage. (Although I always thought that the guy who remembered girls names was more likely to get laid...)</p><p>3. There is an upper limit on intelligence for breeding.  I've known plenty of smart guys and gals that felt like reproduction was a waste of their time, so perhaps our breeding process selects against high IQ's.</p></htmltext>
<tokenext>You are making the mistake of assuming that evolution always gives us desirable traits .
Evolution is really not intelligent .
It 's just making random code changes , for our species we get a coherent ( expressible ) mutation about once in every 8 generations.Evolution is only about 1 thing , breeding .
If an individual has more babies than another individual then his genes are selected for.Three possibilities that I can come up with : 1 .
Random mutations have n't yet given our species overproduction of this receptor protein .
I 'm going out on a limb here and assuming that they got over-expression by repeating the gene sequence .
Tandem duplications usually happen in specific places in the genome where the DNA replication enzymes get " stuck " when replicating the parent strand , causing repeats.2 .
Over-expression of this protein does n't give any kind of fitness ( for reproduction ) advantage .
( Although I always thought that the guy who remembered girls names was more likely to get laid... ) 3 .
There is an upper limit on intelligence for breeding .
I 've known plenty of smart guys and gals that felt like reproduction was a waste of their time , so perhaps our breeding process selects against high IQ 's .</tokentext>
<sentencetext>You are making the mistake of assuming that evolution always gives us desirable traits.
Evolution is really not intelligent.
It's just making random code changes, for our species we get a coherent (expressible) mutation about once in every 8 generations.Evolution is only about 1 thing, breeding.
If an individual has more babies than another individual then his genes are selected for.Three possibilities that I can come up with:1.
Random mutations haven't yet given our species overproduction of this receptor protein.
I'm going out on a limb here and assuming that they got over-expression by repeating the gene sequence.
Tandem duplications usually happen in specific places in the genome where the DNA replication enzymes get "stuck" when replicating the parent strand, causing repeats.2.
Over-expression of this protein doesn't give any kind of fitness (for reproduction) advantage.
(Although I always thought that the guy who remembered girls names was more likely to get laid...)3.
There is an upper limit on intelligence for breeding.
I've known plenty of smart guys and gals that felt like reproduction was a waste of their time, so perhaps our breeding process selects against high IQ's.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963794</id>
	<title>So the meaning of life changes?</title>
	<author>Anonymous</author>
	<datestamp>1257265680000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>  3 * 42 = 126?</p><p>or does this work exponentially<nobr> <wbr></nobr>:)</p><p>Strangely enough, but to prove I am not a bot in a post about evolving mice I needed to type <b>evolve</b> into the textfield.</p></htmltext>
<tokenext>3 * 42 = 126 ? or does this work exponentially : ) Strangely enough , but to prove I am not a bot in a post about evolving mice I needed to type evolve into the textfield .</tokentext>
<sentencetext>  3 * 42 = 126?or does this work exponentially :)Strangely enough, but to prove I am not a bot in a post about evolving mice I needed to type evolve into the textfield.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963804</id>
	<title>Rat 2.0 : Modern Rat</title>
	<author>slyborg</author>
	<datestamp>1257265740000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>Special upgrade pricing - 25\% off with trade-in of your old rat.</p></htmltext>
<tokenext>Special upgrade pricing - 25 \ % off with trade-in of your old rat .</tokentext>
<sentencetext>Special upgrade pricing - 25\% off with trade-in of your old rat.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964834</id>
	<title>Re:Spooky</title>
	<author>Verteiron</author>
	<datestamp>1257269940000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>It's not banned in the USA. Where are you?</p></htmltext>
<tokenext>It 's not banned in the USA .
Where are you ?</tokentext>
<sentencetext>It's not banned in the USA.
Where are you?</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964338</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29966348</id>
	<title>Re:Rat 2.0 : Modern Rat</title>
	<author>Deliveranc3</author>
	<datestamp>1257276720000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>When will we get a rat made of stainless steel.</htmltext>
<tokenext>When will we get a rat made of stainless steel .</tokentext>
<sentencetext>When will we get a rat made of stainless steel.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963804</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964080</id>
	<title>at what cost?</title>
	<author>Lord Ender</author>
	<datestamp>1257266820000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>5</modscore>
	<htmltext><p>Due to his enhanced memory, the rat could not push her out of his mind. The memories refused to fade with time. The slightest sight or scent would cause him not just to remember his intense passion and total devotion, but also to relive it, as if she were still there with him. Moments later, as reality returned, he inevitably re-experienced that October afternoon when she left. The despair cut to the bottom of his soul in a way far more intense than the original break-up had been, as shock had initially numbed his pain. No more. His perfect memory of perfect happiness lifted him up so high, the inevitable fall came from an unimaginable height, and terminal velocity does not apply to emotions.</p><p>After enduring this torture for what seemed an eternity, he finally gave in, and resolutely marched toward the wire-framed cheese, her angelic body still vivid in his mind...</p></htmltext>
<tokenext>Due to his enhanced memory , the rat could not push her out of his mind .
The memories refused to fade with time .
The slightest sight or scent would cause him not just to remember his intense passion and total devotion , but also to relive it , as if she were still there with him .
Moments later , as reality returned , he inevitably re-experienced that October afternoon when she left .
The despair cut to the bottom of his soul in a way far more intense than the original break-up had been , as shock had initially numbed his pain .
No more .
His perfect memory of perfect happiness lifted him up so high , the inevitable fall came from an unimaginable height , and terminal velocity does not apply to emotions.After enduring this torture for what seemed an eternity , he finally gave in , and resolutely marched toward the wire-framed cheese , her angelic body still vivid in his mind.. .</tokentext>
<sentencetext>Due to his enhanced memory, the rat could not push her out of his mind.
The memories refused to fade with time.
The slightest sight or scent would cause him not just to remember his intense passion and total devotion, but also to relive it, as if she were still there with him.
Moments later, as reality returned, he inevitably re-experienced that October afternoon when she left.
The despair cut to the bottom of his soul in a way far more intense than the original break-up had been, as shock had initially numbed his pain.
No more.
His perfect memory of perfect happiness lifted him up so high, the inevitable fall came from an unimaginable height, and terminal velocity does not apply to emotions.After enduring this torture for what seemed an eternity, he finally gave in, and resolutely marched toward the wire-framed cheese, her angelic body still vivid in his mind...</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964670</id>
	<title>Just what the word needs</title>
	<author>Anonymous</author>
	<datestamp>1257269280000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>Thats just what the word needs, a smarter rat. YOU'RE DOING IT WRONG!</p></htmltext>
<tokenext>Thats just what the word needs , a smarter rat .
YOU 'RE DOING IT WRONG !</tokentext>
<sentencetext>Thats just what the word needs, a smarter rat.
YOU'RE DOING IT WRONG!</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963872</id>
	<title>Ah... That is where</title>
	<author>kid\_oliva</author>
	<datestamp>1257265980000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><a href="http://en.wikipedia.org/wiki/Master\_Splinter" title="wikipedia.org" rel="nofollow">Hamato Yoshi</a> [wikipedia.org] got his pet from.</htmltext>
<tokenext>Hamato Yoshi [ wikipedia.org ] got his pet from .</tokentext>
<sentencetext>Hamato Yoshi [wikipedia.org] got his pet from.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29966452</id>
	<title>Re:We already knew it worked for mice</title>
	<author>Deliveranc3</author>
	<datestamp>1257277320000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>Finite intelligence barrier, once you get smart enough you realize life is suffering and give up.<br> <br> Possible issues explained: No Aliens, Neandrathals were smarter than modern man and coming soon suicidal robots!<br> <br> Improved memory flies directly in the face of the human ability for self deception. I like comparing it to the religious thought that we're created in "God's" image, with a left brain and right brain in constant opposition? Designed to be out of control, cool.</htmltext>
<tokenext>Finite intelligence barrier , once you get smart enough you realize life is suffering and give up .
Possible issues explained : No Aliens , Neandrathals were smarter than modern man and coming soon suicidal robots !
Improved memory flies directly in the face of the human ability for self deception .
I like comparing it to the religious thought that we 're created in " God 's " image , with a left brain and right brain in constant opposition ?
Designed to be out of control , cool .</tokentext>
<sentencetext>Finite intelligence barrier, once you get smart enough you realize life is suffering and give up.
Possible issues explained: No Aliens, Neandrathals were smarter than modern man and coming soon suicidal robots!
Improved memory flies directly in the face of the human ability for self deception.
I like comparing it to the religious thought that we're created in "God's" image, with a left brain and right brain in constant opposition?
Designed to be out of control, cool.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29976154</id>
	<title>Re:Memory is an interesting thing</title>
	<author>Veggiesama</author>
	<datestamp>1256991360000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><div class="quote"><p>As someone with a bad memory, I would be very interested in understanding how this actually works within the rat's brain.</p></div><p>Don't worry about it. You'll forget all about it tomorrow.</p></div>
	</htmltext>
<tokenext>As someone with a bad memory , I would be very interested in understanding how this actually works within the rat 's brain.Do n't worry about it .
You 'll forget all about it tomorrow .</tokentext>
<sentencetext>As someone with a bad memory, I would be very interested in understanding how this actually works within the rat's brain.Don't worry about it.
You'll forget all about it tomorrow.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963840</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29968400</id>
	<title>Re:We already knew it worked for mice</title>
	<author>Anonymous</author>
	<datestamp>1257243540000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>Or... as allready mentioned, that will make them nerd rats and thus unnattracttive to females</p></htmltext>
<tokenext>Or... as allready mentioned , that will make them nerd rats and thus unnattracttive to females</tokentext>
<sentencetext>Or... as allready mentioned, that will make them nerd rats and thus unnattracttive to females</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964082</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964782</id>
	<title>Re:We already knew it worked for mice</title>
	<author>kj\_kabaje</author>
	<datestamp>1257269760000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>sweet! better memory *and* a weight loss treatment in one.<nobr> <wbr></nobr>:-P</htmltext>
<tokenext>sweet !
better memory * and * a weight loss treatment in one .
: -P</tokentext>
<sentencetext>sweet!
better memory *and* a weight loss treatment in one.
:-P</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964082</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29965720</id>
	<title>Re:We already knew it worked for mice</title>
	<author>Anonymous</author>
	<datestamp>1257273780000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p><div class="quote"><p>&gt; Presumably, there is some kind of downside that balances that selective<br>&gt; advantage.</p><p>Higher energy requirements would be a good bet.</p></div><p>This would solve overweight problems then aswell - smarter and more goodlooking!</p></div>
	</htmltext>
<tokenext>&gt; Presumably , there is some kind of downside that balances that selective &gt; advantage.Higher energy requirements would be a good bet.This would solve overweight problems then aswell - smarter and more goodlooking !</tokentext>
<sentencetext>&gt; Presumably, there is some kind of downside that balances that selective&gt; advantage.Higher energy requirements would be a good bet.This would solve overweight problems then aswell - smarter and more goodlooking!
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964082</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964250</id>
	<title>Doom doom doom!</title>
	<author>sammysheep</author>
	<datestamp>1257267480000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><i>"The rats have gotten smarter...even problem solving intelligence...you know when that one looks at you, she's figuring things out..."<br>
<br>
"Scientists were so concerned with whether or not they <b>could</b> make the perfect rat, they never stopped to ask if they <b>should!</b>"</i>
<br> <br>
- (Paraphrases  a la J.P.)</htmltext>
<tokenext>" The rats have gotten smarter...even problem solving intelligence...you know when that one looks at you , she 's figuring things out... " " Scientists were so concerned with whether or not they could make the perfect rat , they never stopped to ask if they should !
" - ( Paraphrases a la J.P. )</tokentext>
<sentencetext>"The rats have gotten smarter...even problem solving intelligence...you know when that one looks at you, she's figuring things out..."

"Scientists were so concerned with whether or not they could make the perfect rat, they never stopped to ask if they should!
"
 
- (Paraphrases  a la J.P.)</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29967448</id>
	<title>Re:Spooky</title>
	<author>jeffb (2.718)</author>
	<datestamp>1257239340000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p> <i>Brain Wave</i>, by Poul Anderson.</p></htmltext>
<tokenext>Brain Wave , by Poul Anderson .</tokentext>
<sentencetext> Brain Wave, by Poul Anderson.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963958</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29965936</id>
	<title>Re:Needs much more work</title>
	<author>interkin3tic</author>
	<datestamp>1257274920000</datestamp>
	<modclass>Funny</modclass>
	<modscore>2</modscore>
	<htmltext><p>Since they haven't gotten it to work in humans yet, we'll probably forget about it before...OMG, did you hear the latest on Jon and Kate?!?</p></htmltext>
<tokenext>Since they have n't gotten it to work in humans yet , we 'll probably forget about it before...OMG , did you hear the latest on Jon and Kate ? !
?</tokentext>
<sentencetext>Since they haven't gotten it to work in humans yet, we'll probably forget about it before...OMG, did you hear the latest on Jon and Kate?!
?</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963732</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964332</id>
	<title>Re:Memory is an interesting thing</title>
	<author>clone53421</author>
	<datestamp>1257267780000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>Hmmm... so the event is still there in our memory, we just can't locate it? So this is like increasing the size of the hash table it's indexed with, perhaps...</p></htmltext>
<tokenext>Hmmm... so the event is still there in our memory , we just ca n't locate it ?
So this is like increasing the size of the hash table it 's indexed with , perhaps.. .</tokentext>
<sentencetext>Hmmm... so the event is still there in our memory, we just can't locate it?
So this is like increasing the size of the hash table it's indexed with, perhaps...</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963840</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29974194</id>
	<title>Re:We already knew it worked for mice</title>
	<author>Planx\_Constant</author>
	<datestamp>1257274260000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>You would make a good point if it weren't for the fact that people keep  <a href="http://www.gifteddevelopment.com/Whats\_New/flynn.htm" title="gifteddevelopment.com" rel="nofollow">getting</a> [gifteddevelopment.com] <a href="http://www.indiana.edu/~intell/flynneffect.shtml" title="indiana.edu" rel="nofollow">smarter</a> [indiana.edu].</htmltext>
<tokenext>You would make a good point if it were n't for the fact that people keep getting [ gifteddevelopment.com ] smarter [ indiana.edu ] .</tokentext>
<sentencetext>You would make a good point if it weren't for the fact that people keep  getting [gifteddevelopment.com] smarter [indiana.edu].</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29966146</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963822</id>
	<title>Finally, Something To Replace</title>
	<author>Anonymous</author>
	<datestamp>1257265800000</datestamp>
	<modclass>Offtopic</modclass>
	<modscore>-1</modscore>
	<htmltext><p>the illiterate and innumerate U.S.A. population.</p><p>From <a href="http://en.wikipedia.org/wiki/Literacy\_in\_the\_United\_States" title="wikipedia.org" rel="nofollow">Literacy In the U.S.A.</a> [wikipedia.org] :</p><p>"Thus, if this bottom quantile of the study is equated with the functionally illiterate, and these are then removed from those classified as literate, then the resultant literacy rate for the United States would be at most 65-85\% depending on where in the basic, minimal competence quantile one sets the cutoff."</p><p>Yous In Baikonur,<br>Kilgore T.</p></htmltext>
<tokenext>the illiterate and innumerate U.S.A. population.From Literacy In the U.S.A. [ wikipedia.org ] : " Thus , if this bottom quantile of the study is equated with the functionally illiterate , and these are then removed from those classified as literate , then the resultant literacy rate for the United States would be at most 65-85 \ % depending on where in the basic , minimal competence quantile one sets the cutoff .
" Yous In Baikonur,Kilgore T .</tokentext>
<sentencetext>the illiterate and innumerate U.S.A. population.From Literacy In the U.S.A. [wikipedia.org] :"Thus, if this bottom quantile of the study is equated with the functionally illiterate, and these are then removed from those classified as literate, then the resultant literacy rate for the United States would be at most 65-85\% depending on where in the basic, minimal competence quantile one sets the cutoff.
"Yous In Baikonur,Kilgore T.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29966520</id>
	<title>Re:We already knew it worked for mice</title>
	<author>I'm not really here</author>
	<datestamp>1257277680000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>I don't know about you, but I think there is some value to having the ability to forget.  Once I've forgiven someone for something, I want my mind to slowly lose that information because it is no longer relevant.  If I remembered everything I ever experienced, I think I'd go insane and become overly depressed as the memories of small infractions mounted (we all forget the little things people do every day that annoy us, or if we don't we resent others for their actions... this could be amplified with perfect memory, no?).<br> <br>Just shooting the breeze here, but perhaps this has been selectively weeded out because those with perfect memory are miserable, or those with perfect memory annoy the crap out of others, and early man killed off the annoying members of society... just a thought.</htmltext>
<tokenext>I do n't know about you , but I think there is some value to having the ability to forget .
Once I 've forgiven someone for something , I want my mind to slowly lose that information because it is no longer relevant .
If I remembered everything I ever experienced , I think I 'd go insane and become overly depressed as the memories of small infractions mounted ( we all forget the little things people do every day that annoy us , or if we do n't we resent others for their actions... this could be amplified with perfect memory , no ? ) .
Just shooting the breeze here , but perhaps this has been selectively weeded out because those with perfect memory are miserable , or those with perfect memory annoy the crap out of others , and early man killed off the annoying members of society... just a thought .</tokentext>
<sentencetext>I don't know about you, but I think there is some value to having the ability to forget.
Once I've forgiven someone for something, I want my mind to slowly lose that information because it is no longer relevant.
If I remembered everything I ever experienced, I think I'd go insane and become overly depressed as the memories of small infractions mounted (we all forget the little things people do every day that annoy us, or if we don't we resent others for their actions... this could be amplified with perfect memory, no?).
Just shooting the breeze here, but perhaps this has been selectively weeded out because those with perfect memory are miserable, or those with perfect memory annoy the crap out of others, and early man killed off the annoying members of society... just a thought.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963958</id>
	<title>Re:Spooky</title>
	<author>Rogerborg</author>
	<datestamp>1257266340000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>2</modscore>
	<htmltext><p>The name escapes me, but I read a SF story that speculated on that.  With super intelligent mice, rats, cats and dogs, the rats and cats ate the mice, the dogs ate the cats, then the really smart ones teamed up with people against the rats and other dogs.

</p><p>Fair point, they'd be smart enough to realise the value of opposable thumbs.  Using can openers for one thing.</p></htmltext>
<tokenext>The name escapes me , but I read a SF story that speculated on that .
With super intelligent mice , rats , cats and dogs , the rats and cats ate the mice , the dogs ate the cats , then the really smart ones teamed up with people against the rats and other dogs .
Fair point , they 'd be smart enough to realise the value of opposable thumbs .
Using can openers for one thing .</tokentext>
<sentencetext>The name escapes me, but I read a SF story that speculated on that.
With super intelligent mice, rats, cats and dogs, the rats and cats ate the mice, the dogs ate the cats, then the really smart ones teamed up with people against the rats and other dogs.
Fair point, they'd be smart enough to realise the value of opposable thumbs.
Using can openers for one thing.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963762</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964866</id>
	<title>Re:We already knew it worked for mice</title>
	<author>tgibbs</author>
	<datestamp>1257270000000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><blockquote><div><p>There is a third possibility, namely that the set of mutations necessary to give rise to this advantage are too improbable to occur (or perhaps even fundamentally impossible).</p></div></blockquote><p>If it were something complicated, like multiple specific mutations or introduction of a gene that the animal doesn't have to begin with, this is plausible. But this is merely increasing the expression of a gene that is already there, and there are multiple regulatory mechanisms, both genomic and postgenomic that control its abundance on neurons. So it is difficult to imagine that there is not underlying variation in expression levels that natural selection could use to further optimize its expression.</p></div>
	</htmltext>
<tokenext>There is a third possibility , namely that the set of mutations necessary to give rise to this advantage are too improbable to occur ( or perhaps even fundamentally impossible ) .If it were something complicated , like multiple specific mutations or introduction of a gene that the animal does n't have to begin with , this is plausible .
But this is merely increasing the expression of a gene that is already there , and there are multiple regulatory mechanisms , both genomic and postgenomic that control its abundance on neurons .
So it is difficult to imagine that there is not underlying variation in expression levels that natural selection could use to further optimize its expression .</tokentext>
<sentencetext>There is a third possibility, namely that the set of mutations necessary to give rise to this advantage are too improbable to occur (or perhaps even fundamentally impossible).If it were something complicated, like multiple specific mutations or introduction of a gene that the animal doesn't have to begin with, this is plausible.
But this is merely increasing the expression of a gene that is already there, and there are multiple regulatory mechanisms, both genomic and postgenomic that control its abundance on neurons.
So it is difficult to imagine that there is not underlying variation in expression levels that natural selection could use to further optimize its expression.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964324</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963836</id>
	<title>Any news on Charlie?</title>
	<author>jeffmeden</author>
	<datestamp>1257265860000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>I will spring for the flowers, Charlie.  Just don't act like a jerk.</p></htmltext>
<tokenext>I will spring for the flowers , Charlie .
Just do n't act like a jerk .</tokentext>
<sentencetext>I will spring for the flowers, Charlie.
Just don't act like a jerk.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29967888</id>
	<title>Re:Spooky</title>
	<author>Anonymous</author>
	<datestamp>1257241440000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext>There's no need to fear!  UnderDog is here!</htmltext>
<tokenext>There 's no need to fear !
UnderDog is here !</tokentext>
<sentencetext>There's no need to fear!
UnderDog is here!</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963762</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29966146</id>
	<title>Re:We already knew it worked for mice</title>
	<author>ortholattice</author>
	<datestamp>1257275820000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>3</modscore>
	<htmltext><blockquote><div><p>As you suggest, there are two possibilities why this advantage hasn't occurred naturally:
            </p><p>
1. It adds no selective advantage;
               </p><p>
2. The advantage is outweighed by the costs.
                  </p><p>
There is a third possibility, namely that the set of mutations necessary
to give rise to this advantage are too improbable to occur (or perhaps
even fundamentally impossible).</p></div>
</blockquote><p>

Maybe there is a 4th possibility.  Everyone seems to be focusing on
"survivability", but once that is overcome,
reproduction becomes important.  Look at the ostentatious displays
of some birds that have nothing to do with survivability or
might even be detrimental to it.
Maybe a highly intelligent
rat  simply becomes less interested in sex, or is less able to
attract females who might prefer the dumb macho rats.
I don't know if a comparison to humans has any
validity, but the
most intelligent of our species are not necessarily the ones
reproducing the most (or in some cases at all).
This is in spite of the fact that we are intelligent
enough to understand logically what is necessary to propagate
our genes.  In terms of the long-term evolution of humans,
intelligence doesn't seem to be one of the characteristics we are
selecting for, for better or worse.</p></div>
	</htmltext>
<tokenext>As you suggest , there are two possibilities why this advantage has n't occurred naturally : 1 .
It adds no selective advantage ; 2 .
The advantage is outweighed by the costs .
There is a third possibility , namely that the set of mutations necessary to give rise to this advantage are too improbable to occur ( or perhaps even fundamentally impossible ) .
Maybe there is a 4th possibility .
Everyone seems to be focusing on " survivability " , but once that is overcome , reproduction becomes important .
Look at the ostentatious displays of some birds that have nothing to do with survivability or might even be detrimental to it .
Maybe a highly intelligent rat simply becomes less interested in sex , or is less able to attract females who might prefer the dumb macho rats .
I do n't know if a comparison to humans has any validity , but the most intelligent of our species are not necessarily the ones reproducing the most ( or in some cases at all ) .
This is in spite of the fact that we are intelligent enough to understand logically what is necessary to propagate our genes .
In terms of the long-term evolution of humans , intelligence does n't seem to be one of the characteristics we are selecting for , for better or worse .</tokentext>
<sentencetext>As you suggest, there are two possibilities why this advantage hasn't occurred naturally:
            
1.
It adds no selective advantage;
               
2.
The advantage is outweighed by the costs.
There is a third possibility, namely that the set of mutations necessary
to give rise to this advantage are too improbable to occur (or perhaps
even fundamentally impossible).
Maybe there is a 4th possibility.
Everyone seems to be focusing on
"survivability", but once that is overcome,
reproduction becomes important.
Look at the ostentatious displays
of some birds that have nothing to do with survivability or
might even be detrimental to it.
Maybe a highly intelligent
rat  simply becomes less interested in sex, or is less able to
attract females who might prefer the dumb macho rats.
I don't know if a comparison to humans has any
validity, but the
most intelligent of our species are not necessarily the ones
reproducing the most (or in some cases at all).
This is in spite of the fact that we are intelligent
enough to understand logically what is necessary to propagate
our genes.
In terms of the long-term evolution of humans,
intelligence doesn't seem to be one of the characteristics we are
selecting for, for better or worse.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964324</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29965012</id>
	<title>Re:Hmmmm . . . .</title>
	<author>Abstrackt</author>
	<datestamp>1257270720000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><div class="quote"><p>Biological overclocking.  How long before they try nitrogen cooling?</p></div><p>In other news, "Ratsicles" will soon be available in your grocer's freezer.</p></div>
	</htmltext>
<tokenext>Biological overclocking .
How long before they try nitrogen cooling ? In other news , " Ratsicles " will soon be available in your grocer 's freezer .</tokentext>
<sentencetext>Biological overclocking.
How long before they try nitrogen cooling?In other news, "Ratsicles" will soon be available in your grocer's freezer.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964048</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29966982</id>
	<title>Re:at what cost?</title>
	<author>alvinrod</author>
	<datestamp>1257280320000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>Simply beautiful.</htmltext>
<tokenext>Simply beautiful .</tokentext>
<sentencetext>Simply beautiful.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964080</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964048</id>
	<title>Hmmmm . . . .</title>
	<author>Anonymous</author>
	<datestamp>1257266700000</datestamp>
	<modclass>Funny</modclass>
	<modscore>1</modscore>
	<htmltext><p>Biological overclocking.  How long before they try nitrogen cooling?</p></htmltext>
<tokenext>Biological overclocking .
How long before they try nitrogen cooling ?</tokentext>
<sentencetext>Biological overclocking.
How long before they try nitrogen cooling?</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29965676</id>
	<title>Re:The world needs this....</title>
	<author>snspdaarf</author>
	<datestamp>1257273600000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><div class="quote"><p> And humanity will actually be able to learn from mistakes made in the past. </p></div><p>Yeah, "In the future, don't dick around with the rat's genetics."</p></div>
	</htmltext>
<tokenext>And humanity will actually be able to learn from mistakes made in the past .
Yeah , " In the future , do n't dick around with the rat 's genetics .
"</tokentext>
<sentencetext> And humanity will actually be able to learn from mistakes made in the past.
Yeah, "In the future, don't dick around with the rat's genetics.
"
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963978</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964574</id>
	<title>Re:I for one</title>
	<author>Xaedalus</author>
	<datestamp>1257268920000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>Actually, I applaud you for using your user name!</htmltext>
<tokenext>Actually , I applaud you for using your user name !</tokentext>
<sentencetext>Actually, I applaud you for using your user name!</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963726</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963928</id>
	<title>Intellligence and Genes</title>
	<author>Anonymous</author>
	<datestamp>1257266220000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>So we are all agreed then that genes can have a major impact on intelligence? And it follows then that like the genes for say height and pigmentation, the genes that contribute to intelligence have different distribution patterns in different populations? And that James Watson was unfairly pilloried for his opinions on this matter?</p></htmltext>
<tokenext>So we are all agreed then that genes can have a major impact on intelligence ?
And it follows then that like the genes for say height and pigmentation , the genes that contribute to intelligence have different distribution patterns in different populations ?
And that James Watson was unfairly pilloried for his opinions on this matter ?</tokentext>
<sentencetext>So we are all agreed then that genes can have a major impact on intelligence?
And it follows then that like the genes for say height and pigmentation, the genes that contribute to intelligence have different distribution patterns in different populations?
And that James Watson was unfairly pilloried for his opinions on this matter?</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964354</id>
	<title>Re:at what cost?</title>
	<author>Anonymous</author>
	<datestamp>1257267900000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>Don't worry.  Once science comes up with a cure for sex, your rat will be able to move on to something else.</p></htmltext>
<tokenext>Do n't worry .
Once science comes up with a cure for sex , your rat will be able to move on to something else .</tokentext>
<sentencetext>Don't worry.
Once science comes up with a cure for sex, your rat will be able to move on to something else.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964080</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963904</id>
	<title>Re:I for one</title>
	<author>Jhon</author>
	<datestamp>1257266040000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>2</modscore>
	<htmltext><p>Seeing these posts is like listing to Monty Python's "I Like Traffic Lights" song.</p></htmltext>
<tokenext>Seeing these posts is like listing to Monty Python 's " I Like Traffic Lights " song .</tokentext>
<sentencetext>Seeing these posts is like listing to Monty Python's "I Like Traffic Lights" song.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963726</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963726</id>
	<title>I for one</title>
	<author>Anonymous</author>
	<datestamp>1257265380000</datestamp>
	<modclass>None</modclass>
	<modscore>-1</modscore>
	<htmltext><p>welcome our new Rat Bastard overlords!</p></htmltext>
<tokenext>welcome our new Rat Bastard overlords !</tokentext>
<sentencetext>welcome our new Rat Bastard overlords!</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963762</id>
	<title>Spooky</title>
	<author>chebucto</author>
	<datestamp>1257265560000</datestamp>
	<modclass>Funny</modclass>
	<modscore>1</modscore>
	<htmltext><p>While I know that this sort of research is ultimately aimed at improving human life, for some reason I can't shake the image of a mad scientist making super-smart dogs, the experiment going awry, and an apocalyptic future of human-pitbull wars.</p></htmltext>
<tokenext>While I know that this sort of research is ultimately aimed at improving human life , for some reason I ca n't shake the image of a mad scientist making super-smart dogs , the experiment going awry , and an apocalyptic future of human-pitbull wars .</tokentext>
<sentencetext>While I know that this sort of research is ultimately aimed at improving human life, for some reason I can't shake the image of a mad scientist making super-smart dogs, the experiment going awry, and an apocalyptic future of human-pitbull wars.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29969444</id>
	<title>Re:Other Rodent Upgrade Experiments</title>
	<author>j\_cavera</author>
	<datestamp>1257247440000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>Mantis shrimp eyes would be f-ing cool!</p></htmltext>
<tokenext>Mantis shrimp eyes would be f-ing cool !</tokentext>
<sentencetext>Mantis shrimp eyes would be f-ing cool!</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964232</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29966364</id>
	<title>Re:We already knew it worked for mice</title>
	<author>relguj9</author>
	<datestamp>1257276840000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>Or (IMHO) the most probable presumption is that rats are not at the peak of their evolution and this particular trait just hasn't occurred yet or would not be a naturally occurring mutation.<br> <br>

Your presumption that "if they haven't evolved to do this yet then there must be some disadvantage" is inherently false.<br> <br>

To extrapolate further, using your presumption, "if rats were humans they'd have an evolutionary advantage, why aren't rats humans".  I would imagine one could list a million "simple mutations", each giving an advantage, that would lead to a rat having all of the genetic advantages of humans.  Why haven't each of these in the chain occurred?<br> <br>

Evolution is not necessarily really even about selective advantage or survival of the fittest.  It's about who reproduces the most (which is not necessarily the fittest or most advantaged).  In fact, evolution only seems to really accelerate in extreme conditions.<br> <br>

Anyways, I'm going on too far, but I reject your presumption that a genetic advantage must necessarily have a disadvantage if it isn't naturally occurring.</htmltext>
<tokenext>Or ( IMHO ) the most probable presumption is that rats are not at the peak of their evolution and this particular trait just has n't occurred yet or would not be a naturally occurring mutation .
Your presumption that " if they have n't evolved to do this yet then there must be some disadvantage " is inherently false .
To extrapolate further , using your presumption , " if rats were humans they 'd have an evolutionary advantage , why are n't rats humans " .
I would imagine one could list a million " simple mutations " , each giving an advantage , that would lead to a rat having all of the genetic advantages of humans .
Why have n't each of these in the chain occurred ?
Evolution is not necessarily really even about selective advantage or survival of the fittest .
It 's about who reproduces the most ( which is not necessarily the fittest or most advantaged ) .
In fact , evolution only seems to really accelerate in extreme conditions .
Anyways , I 'm going on too far , but I reject your presumption that a genetic advantage must necessarily have a disadvantage if it is n't naturally occurring .</tokentext>
<sentencetext>Or (IMHO) the most probable presumption is that rats are not at the peak of their evolution and this particular trait just hasn't occurred yet or would not be a naturally occurring mutation.
Your presumption that "if they haven't evolved to do this yet then there must be some disadvantage" is inherently false.
To extrapolate further, using your presumption, "if rats were humans they'd have an evolutionary advantage, why aren't rats humans".
I would imagine one could list a million "simple mutations", each giving an advantage, that would lead to a rat having all of the genetic advantages of humans.
Why haven't each of these in the chain occurred?
Evolution is not necessarily really even about selective advantage or survival of the fittest.
It's about who reproduces the most (which is not necessarily the fittest or most advantaged).
In fact, evolution only seems to really accelerate in extreme conditions.
Anyways, I'm going on too far, but I reject your presumption that a genetic advantage must necessarily have a disadvantage if it isn't naturally occurring.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29965456</id>
	<title>Re:The world needs this....</title>
	<author>hairykrishna</author>
	<datestamp>1257272580000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>Don't be daft. They used rats because they're a standard experimental animal not because they want to make some kind of super rodents. Research it rats is often applicable in other species; like humans.</p></htmltext>
<tokenext>Do n't be daft .
They used rats because they 're a standard experimental animal not because they want to make some kind of super rodents .
Research it rats is often applicable in other species ; like humans .</tokentext>
<sentencetext>Don't be daft.
They used rats because they're a standard experimental animal not because they want to make some kind of super rodents.
Research it rats is often applicable in other species; like humans.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963814</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964654</id>
	<title>Re:The rats' name is not 'Algernon', or is it?</title>
	<author>OshMan</author>
	<datestamp>1257269220000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>Me too, but if there are any younger folks on the list perhaps N.I.M.H or even "the Brain" would strike the same nerve.</htmltext>
<tokenext>Me too , but if there are any younger folks on the list perhaps N.I.M.H or even " the Brain " would strike the same nerve .</tokentext>
<sentencetext>Me too, but if there are any younger folks on the list perhaps N.I.M.H or even "the Brain" would strike the same nerve.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963778</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964582</id>
	<title>I'll say it now...</title>
	<author>fahrbot-bot</author>
	<datestamp>1257268920000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>Continued progress along these lines won't end well for us.<br>
Did we learn nothing from <a href="http://en.wikipedia.org/wiki/Deep\_Blue\_Sea" title="wikipedia.org">Deep Blue Sea</a> [wikipedia.org]? (Or this: <a href="http://www.microsoft.com/hardware/mouseandkeyboard/ProductDetails.aspx?pid=003" title="microsoft.com">IntelliMouse</a> [microsoft.com]?)<br>
I, for one, welcome &lt;you know the rest...&gt;</htmltext>
<tokenext>Continued progress along these lines wo n't end well for us .
Did we learn nothing from Deep Blue Sea [ wikipedia.org ] ?
( Or this : IntelliMouse [ microsoft.com ] ?
) I , for one , welcome</tokentext>
<sentencetext>Continued progress along these lines won't end well for us.
Did we learn nothing from Deep Blue Sea [wikipedia.org]?
(Or this: IntelliMouse [microsoft.com]?
)
I, for one, welcome </sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963978</id>
	<title>Re:The world needs this....</title>
	<author>captainpanic</author>
	<datestamp>1257266460000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>The world doesn't need this rat.<br>But perhaps our kids will actually also have a better memory because of it. Then they can all still remember the history lessons they learned in school when they get to a position of power. And humanity will actually be able to learn from mistakes made in the past. And the world will be a better place. Free drinks for everyone.</p></htmltext>
<tokenext>The world does n't need this rat.But perhaps our kids will actually also have a better memory because of it .
Then they can all still remember the history lessons they learned in school when they get to a position of power .
And humanity will actually be able to learn from mistakes made in the past .
And the world will be a better place .
Free drinks for everyone .</tokentext>
<sentencetext>The world doesn't need this rat.But perhaps our kids will actually also have a better memory because of it.
Then they can all still remember the history lessons they learned in school when they get to a position of power.
And humanity will actually be able to learn from mistakes made in the past.
And the world will be a better place.
Free drinks for everyone.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963814</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29974280</id>
	<title>Re:We already knew it worked for mice</title>
	<author>Garrett Fox</author>
	<datestamp>1257274920000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>I think that experiment was part of a sequence that also showed the gene affected seizures, so maybe that particular boost had dangerous side effects.</htmltext>
<tokenext>I think that experiment was part of a sequence that also showed the gene affected seizures , so maybe that particular boost had dangerous side effects .</tokentext>
<sentencetext>I think that experiment was part of a sequence that also showed the gene affected seizures, so maybe that particular boost had dangerous side effects.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29966912</id>
	<title>Hmmm...entirely different first thought....</title>
	<author>sgt\_doom</author>
	<datestamp>1257279900000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>That's weird.  I was sure this was another article about Wall Street and derivatives dealers.</p></htmltext>
<tokenext>That 's weird .
I was sure this was another article about Wall Street and derivatives dealers .</tokentext>
<sentencetext>That's weird.
I was sure this was another article about Wall Street and derivatives dealers.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963778</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964372</id>
	<title>We need this like a hole in the head...</title>
	<author>tjstork</author>
	<datestamp>1257267960000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>Man, that's all we need, to succumb to a plague of genetically engineered rats.</p></htmltext>
<tokenext>Man , that 's all we need , to succumb to a plague of genetically engineered rats .</tokentext>
<sentencetext>Man, that's all we need, to succumb to a plague of genetically engineered rats.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964766</id>
	<title>... the dark side ... sort of</title>
	<author>electricprof</author>
	<datestamp>1257269640000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>Unfortunately, attempts at breeding smarter rats has lead to an overpopulation of overpaid finance executives.  Meanwhile, current research on engineering an ethical politician has hit a brick wall<nobr> <wbr></nobr>...</htmltext>
<tokenext>Unfortunately , attempts at breeding smarter rats has lead to an overpopulation of overpaid finance executives .
Meanwhile , current research on engineering an ethical politician has hit a brick wall .. .</tokentext>
<sentencetext>Unfortunately, attempts at breeding smarter rats has lead to an overpopulation of overpaid finance executives.
Meanwhile, current research on engineering an ethical politician has hit a brick wall ...</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963990</id>
	<title>Re:Spooky</title>
	<author>oldspewey</author>
	<datestamp>1257266520000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>As long as it stars Will Smith as a loner-scientist who drives a Shelby GT-500 it should be pretty good.</htmltext>
<tokenext>As long as it stars Will Smith as a loner-scientist who drives a Shelby GT-500 it should be pretty good .</tokentext>
<sentencetext>As long as it stars Will Smith as a loner-scientist who drives a Shelby GT-500 it should be pretty good.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963762</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964302</id>
	<title>Re:We already knew it worked for mice</title>
	<author>tgibbs</author>
	<datestamp>1257267660000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><blockquote><div><p>Higher energy requirements would be a good bet.</p></div></blockquote><p>It's a possibility, but I don't think so. The receptors don't use a lot of energy. The baseline cost of maintaining the neurons won't change. So the main incremental cost will be the pump costs for repolarizing after action potentials. But it doesn't seem likely that overall firing is massively increased, or they'd probably be seizing.</p></div>
	</htmltext>
<tokenext>Higher energy requirements would be a good bet.It 's a possibility , but I do n't think so .
The receptors do n't use a lot of energy .
The baseline cost of maintaining the neurons wo n't change .
So the main incremental cost will be the pump costs for repolarizing after action potentials .
But it does n't seem likely that overall firing is massively increased , or they 'd probably be seizing .</tokentext>
<sentencetext>Higher energy requirements would be a good bet.It's a possibility, but I don't think so.
The receptors don't use a lot of energy.
The baseline cost of maintaining the neurons won't change.
So the main incremental cost will be the pump costs for repolarizing after action potentials.
But it doesn't seem likely that overall firing is massively increased, or they'd probably be seizing.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964082</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29966560</id>
	<title>Re:We already knew it worked for mice</title>
	<author>(arg!)Styopa</author>
	<datestamp>1257277860000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>"Nevertheless, it raises an interesting question: if intelligence can be increased by something so simple as an increase in the expression of a single NMDA receptor subunit, why hasn't it already happened?"</p><p>Looking back at great swaths of my own life, and imagining the ability to remember them much, much better, the reason becomes apparent: suicide?</p></htmltext>
<tokenext>" Nevertheless , it raises an interesting question : if intelligence can be increased by something so simple as an increase in the expression of a single NMDA receptor subunit , why has n't it already happened ?
" Looking back at great swaths of my own life , and imagining the ability to remember them much , much better , the reason becomes apparent : suicide ?</tokentext>
<sentencetext>"Nevertheless, it raises an interesting question: if intelligence can be increased by something so simple as an increase in the expression of a single NMDA receptor subunit, why hasn't it already happened?
"Looking back at great swaths of my own life, and imagining the ability to remember them much, much better, the reason becomes apparent: suicide?</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29967656</id>
	<title>Re:We already knew it worked for mice</title>
	<author>The Dancing Panda</author>
	<datestamp>1257240420000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>You act like the third possibility is far-fetched. I'd say that's what happens more often than not. We're not in the best of all possible worlds, not every genetic mutation that provides a survival advantage necessarily thrives. <br> <br>Maybe the rats that have had this mutation were also nerd rats that couldn't get laid. It happens.</htmltext>
<tokenext>You act like the third possibility is far-fetched .
I 'd say that 's what happens more often than not .
We 're not in the best of all possible worlds , not every genetic mutation that provides a survival advantage necessarily thrives .
Maybe the rats that have had this mutation were also nerd rats that could n't get laid .
It happens .</tokentext>
<sentencetext>You act like the third possibility is far-fetched.
I'd say that's what happens more often than not.
We're not in the best of all possible worlds, not every genetic mutation that provides a survival advantage necessarily thrives.
Maybe the rats that have had this mutation were also nerd rats that couldn't get laid.
It happens.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964324</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29965542</id>
	<title>got to be a joke about...</title>
	<author>cellocgw</author>
	<datestamp>1257273000000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>Somewhere a joke about the Stainless Steel Rat is waiting to appear, but I can't find it.  Clearly I need some of that memory enhancement.</p></htmltext>
<tokenext>Somewhere a joke about the Stainless Steel Rat is waiting to appear , but I ca n't find it .
Clearly I need some of that memory enhancement .</tokentext>
<sentencetext>Somewhere a joke about the Stainless Steel Rat is waiting to appear, but I can't find it.
Clearly I need some of that memory enhancement.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29977960</id>
	<title>Re:Spooky</title>
	<author>Chris Burke</author>
	<datestamp>1257003660000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><i>The name escapes me, but I read a SF story that speculated on that. With super intelligent mice, rats, cats and dogs, the rats and cats ate the mice, the dogs ate the cats, then the really smart ones teamed up with people against the rats and other dogs. </i></p><p>I saw something similar to what you describe only much more schlocky in the late-80s or early-90s Twilight Zone series.  A pair of young men exploring an abandoned lab find the corpses of giant mutant rats, which had been killed by giant mutant cats, which had been killed by giant mutant dogs, which had, the boys concluded, been killed by "something bigger".  Which turned out to be a giant spider.  Obviously!  The spider was still alive and ate them both.  The end.</p><p>I don't think that series lasted long.<nobr> <wbr></nobr>:P</p></htmltext>
<tokenext>The name escapes me , but I read a SF story that speculated on that .
With super intelligent mice , rats , cats and dogs , the rats and cats ate the mice , the dogs ate the cats , then the really smart ones teamed up with people against the rats and other dogs .
I saw something similar to what you describe only much more schlocky in the late-80s or early-90s Twilight Zone series .
A pair of young men exploring an abandoned lab find the corpses of giant mutant rats , which had been killed by giant mutant cats , which had been killed by giant mutant dogs , which had , the boys concluded , been killed by " something bigger " .
Which turned out to be a giant spider .
Obviously ! The spider was still alive and ate them both .
The end.I do n't think that series lasted long .
: P</tokentext>
<sentencetext>The name escapes me, but I read a SF story that speculated on that.
With super intelligent mice, rats, cats and dogs, the rats and cats ate the mice, the dogs ate the cats, then the really smart ones teamed up with people against the rats and other dogs.
I saw something similar to what you describe only much more schlocky in the late-80s or early-90s Twilight Zone series.
A pair of young men exploring an abandoned lab find the corpses of giant mutant rats, which had been killed by giant mutant cats, which had been killed by giant mutant dogs, which had, the boys concluded, been killed by "something bigger".
Which turned out to be a giant spider.
Obviously!  The spider was still alive and ate them both.
The end.I don't think that series lasted long.
:P</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963958</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964050</id>
	<title>American Bar Association Sees Job Threat</title>
	<author>Capablanca</author>
	<datestamp>1257266700000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>is it true the smart rats escaped and made a beeline to 85 Broad St, NY, NY?</p></htmltext>
<tokenext>is it true the smart rats escaped and made a beeline to 85 Broad St , NY , NY ?</tokentext>
<sentencetext>is it true the smart rats escaped and made a beeline to 85 Broad St, NY, NY?</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964284</id>
	<title>Re: Human testing</title>
	<author>Tristanic</author>
	<datestamp>1257267600000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>...damn, forgot what I was going to say.</htmltext>
<tokenext>...damn , forgot what I was going to say .</tokentext>
<sentencetext>...damn, forgot what I was going to say.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29970498</id>
	<title>Re:The secret...</title>
	<author>VisceralLogic</author>
	<datestamp>1257250800000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><div class="quote"><p><div class="quote"><p>science could bread more intelligent rats</p></div><p>Mmmmmm... breaded rats.</p></div><p>Onna stick!  Inna bun!</p></div>
	</htmltext>
<tokenext>science could bread more intelligent ratsMmmmmm... breaded rats.Onna stick !
Inna bun !</tokentext>
<sentencetext>science could bread more intelligent ratsMmmmmm... breaded rats.Onna stick!
Inna bun!
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964092</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964072</id>
	<title>How the Rat Wars began</title>
	<author>HangingChad</author>
	<datestamp>1257266760000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>At 2:14 am on August 29th, NR2B+ A23, aka "Pinky", became self-aware. After a brief bout of tail chasing, coupled with a sudden realization, "Holy crap, I'm a f'ing rat." Pinky began to fear being shut down by his creators.

</p><p>And so it began....</p></htmltext>
<tokenext>At 2 : 14 am on August 29th , NR2B + A23 , aka " Pinky " , became self-aware .
After a brief bout of tail chasing , coupled with a sudden realization , " Holy crap , I 'm a f'ing rat .
" Pinky began to fear being shut down by his creators .
And so it began... .</tokentext>
<sentencetext>At 2:14 am on August 29th, NR2B+ A23, aka "Pinky", became self-aware.
After a brief bout of tail chasing, coupled with a sudden realization, "Holy crap, I'm a f'ing rat.
" Pinky began to fear being shut down by his creators.
And so it began....</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963760</id>
	<title>The secret...</title>
	<author>mishehu</author>
	<datestamp>1257265560000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext>...of NIMH coming soon...<br> <br>
They always said that science could bread more intelligent rats, but did they REALLY have to???</htmltext>
<tokenext>...of NIMH coming soon.. . They always said that science could bread more intelligent rats , but did they REALLY have to ? ?
?</tokentext>
<sentencetext>...of NIMH coming soon... 
They always said that science could bread more intelligent rats, but did they REALLY have to??
?</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29967744</id>
	<title>Uplift</title>
	<author>Anonymous</author>
	<datestamp>1257240780000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>Good choice in candidate species for uplift there scientists...(NOT)</p></htmltext>
<tokenext>Good choice in candidate species for uplift there scientists... ( NOT )</tokentext>
<sentencetext>Good choice in candidate species for uplift there scientists...(NOT)</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963814</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29965982</id>
	<title>Re:I for one</title>
	<author>Moderatbastard</author>
	<datestamp>1257275160000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext>Thank you, my loyal subject.</htmltext>
<tokenext>Thank you , my loyal subject .</tokentext>
<sentencetext>Thank you, my loyal subject.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963726</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29965622</id>
	<title>Re:at what cost?</title>
	<author>Chris Burke</author>
	<datestamp>1257273360000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>Sounds a little autobiographical.  Indeed, memories can be a curse.  But don't worry, there is someone who can help you.  Maybe you would be interested in making an appointment with <a href="http://en.wikipedia.org/wiki/Eternal\_Sunshine\_of\_the\_Spotless\_Mind" title="wikipedia.org">Lacuna, Inc</a> [wikipedia.org]?</p></htmltext>
<tokenext>Sounds a little autobiographical .
Indeed , memories can be a curse .
But do n't worry , there is someone who can help you .
Maybe you would be interested in making an appointment with Lacuna , Inc [ wikipedia.org ] ?</tokentext>
<sentencetext>Sounds a little autobiographical.
Indeed, memories can be a curse.
But don't worry, there is someone who can help you.
Maybe you would be interested in making an appointment with Lacuna, Inc [wikipedia.org]?</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964080</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964536</id>
	<title>Re:We already knew it worked for mice</title>
	<author>xianthax</author>
	<datestamp>1257268800000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><div class="quote"><p>Presumably, there is some kind of downside that balances that selective advantage.</p></div><p>massive assumption and very wrong from my experience.</p><p>In the US for instance the average high school drop out has more children than the average college graduate.  Quite often you can see that the least educated and least rationally thinking humans end up with the most children, thus are making the larger contribution to the gene pool.  Not that education level is directly correlated to intelligence, but i think there is some link.</p></div>
	</htmltext>
<tokenext>Presumably , there is some kind of downside that balances that selective advantage.massive assumption and very wrong from my experience.In the US for instance the average high school drop out has more children than the average college graduate .
Quite often you can see that the least educated and least rationally thinking humans end up with the most children , thus are making the larger contribution to the gene pool .
Not that education level is directly correlated to intelligence , but i think there is some link .</tokentext>
<sentencetext>Presumably, there is some kind of downside that balances that selective advantage.massive assumption and very wrong from my experience.In the US for instance the average high school drop out has more children than the average college graduate.
Quite often you can see that the least educated and least rationally thinking humans end up with the most children, thus are making the larger contribution to the gene pool.
Not that education level is directly correlated to intelligence, but i think there is some link.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29967532</id>
	<title>Re:The secret...</title>
	<author>CompMD</author>
	<datestamp>1257239820000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>Sony would love to know the secret of NiMH because those batteries don't explode like their Li-Ion ones do.</p></htmltext>
<tokenext>Sony would love to know the secret of NiMH because those batteries do n't explode like their Li-Ion ones do .</tokentext>
<sentencetext>Sony would love to know the secret of NiMH because those batteries don't explode like their Li-Ion ones do.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963760</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963840</id>
	<title>Memory is an interesting thing</title>
	<author>BadAnalogyGuy</author>
	<datestamp>1257265860000</datestamp>
	<modclass>Interestin</modclass>
	<modscore>5</modscore>
	<htmltext><p>Even the most forgetful person can be reminded of an event and recall it with vivid clarity. Alzheimer's sufferers can overcome some of the difficulties of the disease with a device like the <a href="http://www.techcrunch.com/2009/09/06/life-recorders-may-be-this-centurys-wrist-watch/" title="techcrunch.com" rel="nofollow">Life Recorder</a> [techcrunch.com].</p><p>So when we say that someone's (or some rat's) memory is improved, what exactly is improved? Is it the recall ability? If so, does that mean that the rat is somehow able to logically filter out unnecessary information to reach the important memory? Or does it mean that the rat's memory has been structured in a better way? Is it only a spatial thing, or can it work for any type of information?</p><p>As someone with a bad memory, I would be very interested in understanding how this actually works within the rat's brain.</p></htmltext>
<tokenext>Even the most forgetful person can be reminded of an event and recall it with vivid clarity .
Alzheimer 's sufferers can overcome some of the difficulties of the disease with a device like the Life Recorder [ techcrunch.com ] .So when we say that someone 's ( or some rat 's ) memory is improved , what exactly is improved ?
Is it the recall ability ?
If so , does that mean that the rat is somehow able to logically filter out unnecessary information to reach the important memory ?
Or does it mean that the rat 's memory has been structured in a better way ?
Is it only a spatial thing , or can it work for any type of information ? As someone with a bad memory , I would be very interested in understanding how this actually works within the rat 's brain .</tokentext>
<sentencetext>Even the most forgetful person can be reminded of an event and recall it with vivid clarity.
Alzheimer's sufferers can overcome some of the difficulties of the disease with a device like the Life Recorder [techcrunch.com].So when we say that someone's (or some rat's) memory is improved, what exactly is improved?
Is it the recall ability?
If so, does that mean that the rat is somehow able to logically filter out unnecessary information to reach the important memory?
Or does it mean that the rat's memory has been structured in a better way?
Is it only a spatial thing, or can it work for any type of information?As someone with a bad memory, I would be very interested in understanding how this actually works within the rat's brain.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964998</id>
	<title>Re:We already knew it worked for mice</title>
	<author>webdog314</author>
	<datestamp>1257270660000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><div class="quote"><p> Presumably, there is some kind of downside that balances that selective advantage. Are there other behaviors for which the rat is impaired?</p></div><p>Yeah, now they need glasses and can't seem to get a date.</p></div>
	</htmltext>
<tokenext>Presumably , there is some kind of downside that balances that selective advantage .
Are there other behaviors for which the rat is impaired ? Yeah , now they need glasses and ca n't seem to get a date .</tokentext>
<sentencetext> Presumably, there is some kind of downside that balances that selective advantage.
Are there other behaviors for which the rat is impaired?Yeah, now they need glasses and can't seem to get a date.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964698</id>
	<title>Oblig Dr. E - sorry</title>
	<author>Anonymous</author>
	<datestamp>1257269340000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>You know, I have one simple request. And that is to have rats with frickin' heat sinks attached to their heads!</p></htmltext>
<tokenext>You know , I have one simple request .
And that is to have rats with frickin ' heat sinks attached to their heads !</tokentext>
<sentencetext>You know, I have one simple request.
And that is to have rats with frickin' heat sinks attached to their heads!</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963884</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964370</id>
	<title>Uh, can we please make sure these don't escape?</title>
	<author>Anonymous</author>
	<datestamp>1257267960000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>I mean, having genetically modified plants spread through the world is one thing.</p><p>Having basically every animal around us given near chimpansee-like intelligence is an altogether different one.</p><p>Rats can, rarely and under extreme circumstances, eat a lot of different stuff. Including babies. (no kidding: http://www.foxnews.com/story/0,2933,255328,00.html). I would much rather have a stupid rat that starves to death, than an intelligent rat that goes to lengths to get access to stuff to eat. The same for birds and pretty much any other animal. "Intelligent cats" would probably make a great pet idea - but no so great if they start forming cat gangs to ambush and kill dogs.</p></htmltext>
<tokenext>I mean , having genetically modified plants spread through the world is one thing.Having basically every animal around us given near chimpansee-like intelligence is an altogether different one.Rats can , rarely and under extreme circumstances , eat a lot of different stuff .
Including babies .
( no kidding : http : //www.foxnews.com/story/0,2933,255328,00.html ) .
I would much rather have a stupid rat that starves to death , than an intelligent rat that goes to lengths to get access to stuff to eat .
The same for birds and pretty much any other animal .
" Intelligent cats " would probably make a great pet idea - but no so great if they start forming cat gangs to ambush and kill dogs .</tokentext>
<sentencetext>I mean, having genetically modified plants spread through the world is one thing.Having basically every animal around us given near chimpansee-like intelligence is an altogether different one.Rats can, rarely and under extreme circumstances, eat a lot of different stuff.
Including babies.
(no kidding: http://www.foxnews.com/story/0,2933,255328,00.html).
I would much rather have a stupid rat that starves to death, than an intelligent rat that goes to lengths to get access to stuff to eat.
The same for birds and pretty much any other animal.
"Intelligent cats" would probably make a great pet idea - but no so great if they start forming cat gangs to ambush and kill dogs.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29965514</id>
	<title>Re:We already knew it worked for mice</title>
	<author>DaFallus</author>
	<datestamp>1257272820000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><blockquote><div><p>Nevertheless, it raises an interesting question: if intelligence can be increased by something so simple as an increase in the expression of a single NMDA receptor subunit, why hasn't it already happened? Presumably, there is a selective advantage to improved learning and memory. Presumably, there is some kind of downside that balances that selective advantage. Are there other behaviors for which the rat is impaired?</p></div></blockquote><p>

Maybe the smarter rats are more curious and end up as cat food.</p></div>
	</htmltext>
<tokenext>Nevertheless , it raises an interesting question : if intelligence can be increased by something so simple as an increase in the expression of a single NMDA receptor subunit , why has n't it already happened ?
Presumably , there is a selective advantage to improved learning and memory .
Presumably , there is some kind of downside that balances that selective advantage .
Are there other behaviors for which the rat is impaired ?
Maybe the smarter rats are more curious and end up as cat food .</tokentext>
<sentencetext>Nevertheless, it raises an interesting question: if intelligence can be increased by something so simple as an increase in the expression of a single NMDA receptor subunit, why hasn't it already happened?
Presumably, there is a selective advantage to improved learning and memory.
Presumably, there is some kind of downside that balances that selective advantage.
Are there other behaviors for which the rat is impaired?
Maybe the smarter rats are more curious and end up as cat food.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964324</id>
	<title>Re:We already knew it worked for mice</title>
	<author>Anonymous</author>
	<datestamp>1257267780000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>5</modscore>
	<htmltext><p><div class="quote"><p> Presumably, there is a selective advantage to improved learning and memory. Presumably, there is some kind of downside that balances that selective advantage. Are there other behaviors for which the rat is impaired</p></div><p>As you suggest, there are two possibilities why this advantage hasn't occurred naturally:</p><p>1. It adds no selective advantage;</p><p>2. The advantage is outweighed by the costs.</p><p>There is a third possibility, namely that the set of mutations necessary to give rise to this advantage are too improbable to occur (or perhaps even fundamentally impossible).</p><p>Based on no knowledge whatsoever, I suspect that there probably is some selective advantage to higher intelligence in rats, over long enough periods of time. I hypothesize that the rats lack the ability to effectively dissipate heat from a highly active brain, and concurrently those evolutions that allow more effective dissipation of heat (e.g. baldness) are contrary to (or have never occurred concurrent with) the selective advantage of the intelligence. Perhaps we will <a href="http://static.open.salon.com/files/pinky\_brain1253891951.gif" title="salon.com">breed intelligent, bald rats.</a> [salon.com]</p></div>
	</htmltext>
<tokenext>Presumably , there is a selective advantage to improved learning and memory .
Presumably , there is some kind of downside that balances that selective advantage .
Are there other behaviors for which the rat is impairedAs you suggest , there are two possibilities why this advantage has n't occurred naturally : 1 .
It adds no selective advantage ; 2 .
The advantage is outweighed by the costs.There is a third possibility , namely that the set of mutations necessary to give rise to this advantage are too improbable to occur ( or perhaps even fundamentally impossible ) .Based on no knowledge whatsoever , I suspect that there probably is some selective advantage to higher intelligence in rats , over long enough periods of time .
I hypothesize that the rats lack the ability to effectively dissipate heat from a highly active brain , and concurrently those evolutions that allow more effective dissipation of heat ( e.g .
baldness ) are contrary to ( or have never occurred concurrent with ) the selective advantage of the intelligence .
Perhaps we will breed intelligent , bald rats .
[ salon.com ]</tokentext>
<sentencetext> Presumably, there is a selective advantage to improved learning and memory.
Presumably, there is some kind of downside that balances that selective advantage.
Are there other behaviors for which the rat is impairedAs you suggest, there are two possibilities why this advantage hasn't occurred naturally:1.
It adds no selective advantage;2.
The advantage is outweighed by the costs.There is a third possibility, namely that the set of mutations necessary to give rise to this advantage are too improbable to occur (or perhaps even fundamentally impossible).Based on no knowledge whatsoever, I suspect that there probably is some selective advantage to higher intelligence in rats, over long enough periods of time.
I hypothesize that the rats lack the ability to effectively dissipate heat from a highly active brain, and concurrently those evolutions that allow more effective dissipation of heat (e.g.
baldness) are contrary to (or have never occurred concurrent with) the selective advantage of the intelligence.
Perhaps we will breed intelligent, bald rats.
[salon.com]
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964202</id>
	<title>Re:We already knew it worked for mice</title>
	<author>Anonymous</author>
	<datestamp>1257267300000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>If intelligence is a benefit, why aren't all animals already as smart as humans?</p><p>You see... evolution does not work that way. It is not zero-sum. It is not itself intelligent. It is perfectly possible that such a mutation is entirely beneficial, but simply hadn't occurred naturally.</p></htmltext>
<tokenext>If intelligence is a benefit , why are n't all animals already as smart as humans ? You see... evolution does not work that way .
It is not zero-sum .
It is not itself intelligent .
It is perfectly possible that such a mutation is entirely beneficial , but simply had n't occurred naturally .</tokentext>
<sentencetext>If intelligence is a benefit, why aren't all animals already as smart as humans?You see... evolution does not work that way.
It is not zero-sum.
It is not itself intelligent.
It is perfectly possible that such a mutation is entirely beneficial, but simply hadn't occurred naturally.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964778</id>
	<title>Re:at what cost?</title>
	<author>electricprof</author>
	<datestamp>1257269700000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>I need a cigarette.</htmltext>
<tokenext>I need a cigarette .</tokentext>
<sentencetext>I need a cigarette.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964080</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964338</id>
	<title>Re:Spooky</title>
	<author>rastilin</author>
	<datestamp>1257267840000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>2</modscore>
	<htmltext><p><div class="quote"><p>While I know that this sort of research is ultimately aimed at improving human life, for some reason I can't shake the image of a mad scientist making super-smart dogs, the experiment going awry, and an apocalyptic future of human-pitbull wars.</p></div><p>On that note it won't matter even if they succeed. This country is almost certain to ban it on the basis that it gives the beneficiaries an "unethical advantage" over others. After all we already have piracetam which supposedly does something similar, and that's banned.</p></div>
	</htmltext>
<tokenext>While I know that this sort of research is ultimately aimed at improving human life , for some reason I ca n't shake the image of a mad scientist making super-smart dogs , the experiment going awry , and an apocalyptic future of human-pitbull wars.On that note it wo n't matter even if they succeed .
This country is almost certain to ban it on the basis that it gives the beneficiaries an " unethical advantage " over others .
After all we already have piracetam which supposedly does something similar , and that 's banned .</tokentext>
<sentencetext>While I know that this sort of research is ultimately aimed at improving human life, for some reason I can't shake the image of a mad scientist making super-smart dogs, the experiment going awry, and an apocalyptic future of human-pitbull wars.On that note it won't matter even if they succeed.
This country is almost certain to ban it on the basis that it gives the beneficiaries an "unethical advantage" over others.
After all we already have piracetam which supposedly does something similar, and that's banned.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963762</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963732</id>
	<title>Needs much more work</title>
	<author>Anonymous</author>
	<datestamp>1257265440000</datestamp>
	<modclass>Funny</modclass>
	<modscore>5</modscore>
	<htmltext><p>When they can scale it up from lawyers to humans, we might have something useful to talk about.</p></htmltext>
<tokenext>When they can scale it up from lawyers to humans , we might have something useful to talk about .</tokentext>
<sentencetext>When they can scale it up from lawyers to humans, we might have something useful to talk about.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963924</id>
	<title>Gold Fish</title>
	<author>Krneki</author>
	<datestamp>1257266220000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>So what is next? No more gold fish memory jokes?!!!!</htmltext>
<tokenext>So what is next ?
No more gold fish memory jokes ? ! ! !
!</tokentext>
<sentencetext>So what is next?
No more gold fish memory jokes?!!!
!</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29965594</id>
	<title>Re:The world needs this....</title>
	<author>Anonymous</author>
	<datestamp>1257273240000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><div class="quote"><p>We need this about as much as we need a much stronger more deadly flu virus.</p></div><p>This is just a stepping stone to create things that will change the world for the better..</p><p>...For instance,  a monkey with four asses.</p></div>
	</htmltext>
<tokenext>We need this about as much as we need a much stronger more deadly flu virus.This is just a stepping stone to create things that will change the world for the better.....For instance , a monkey with four asses .</tokentext>
<sentencetext>We need this about as much as we need a much stronger more deadly flu virus.This is just a stepping stone to create things that will change the world for the better.....For instance,  a monkey with four asses.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963814</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29965954</id>
	<title>Re:Spooky</title>
	<author>HiThere</author>
	<datestamp>1257275040000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>2</modscore>
	<htmltext><p>Could be "Day of the PagBeasts", alternate title "The Fittest".  I think the author was Edgar Pagborn, but it could be J.T. McIntosh.  Written in the 1940's or 50's.</p><p>I read it once from a library and could never find it again.  It wasn't all *that* good, but there was something compelling me to read it again for something I missed the first time.  Never did find it.  My guess is it never got printed in paperback, and was originally printed in Britain.  Given that it had two titles I suspect that it must have had at least two separate printings.  (I suppose one could have been in some magazine, but not one that I ever encountered.)</p></htmltext>
<tokenext>Could be " Day of the PagBeasts " , alternate title " The Fittest " .
I think the author was Edgar Pagborn , but it could be J.T .
McIntosh. Written in the 1940 's or 50 's.I read it once from a library and could never find it again .
It was n't all * that * good , but there was something compelling me to read it again for something I missed the first time .
Never did find it .
My guess is it never got printed in paperback , and was originally printed in Britain .
Given that it had two titles I suspect that it must have had at least two separate printings .
( I suppose one could have been in some magazine , but not one that I ever encountered .
)</tokentext>
<sentencetext>Could be "Day of the PagBeasts", alternate title "The Fittest".
I think the author was Edgar Pagborn, but it could be J.T.
McIntosh.  Written in the 1940's or 50's.I read it once from a library and could never find it again.
It wasn't all *that* good, but there was something compelling me to read it again for something I missed the first time.
Never did find it.
My guess is it never got printed in paperback, and was originally printed in Britain.
Given that it had two titles I suspect that it must have had at least two separate printings.
(I suppose one could have been in some magazine, but not one that I ever encountered.
)</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963958</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964350</id>
	<title>Going the wrong way around</title>
	<author>Captain Spam</author>
	<datestamp>1257267840000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>So let me get this straight: Scientists gave up on building a better mouse trap, for which the world have beaten a path to their doors, and instead they went the indirect route of building a better <i>rat</i> to chew a path through the world's doors?</p></htmltext>
<tokenext>So let me get this straight : Scientists gave up on building a better mouse trap , for which the world have beaten a path to their doors , and instead they went the indirect route of building a better rat to chew a path through the world 's doors ?</tokentext>
<sentencetext>So let me get this straight: Scientists gave up on building a better mouse trap, for which the world have beaten a path to their doors, and instead they went the indirect route of building a better rat to chew a path through the world's doors?</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963746</id>
	<title>NIMH</title>
	<author>Anonymous</author>
	<datestamp>1257265500000</datestamp>
	<modclass>Funny</modclass>
	<modscore>4</modscore>
	<htmltext><p><a href="http://en.wikipedia.org/wiki/Mrs.\_Frisby\_and\_the\_Rats\_of\_NIMH" title="wikipedia.org">Mrs. Frisby</a> [wikipedia.org] will be pleased...</p></htmltext>
<tokenext>Mrs. Frisby [ wikipedia.org ] will be pleased.. .</tokentext>
<sentencetext>Mrs. Frisby [wikipedia.org] will be pleased...</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29965040</id>
	<title>Re:at what cost?</title>
	<author>Anonymous</author>
	<datestamp>1257270840000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>With their heightened intelligence, wouldn't the rats soon develop a method for brewing alcohol, thus fixing this problem just like humans do?</p></htmltext>
<tokenext>With their heightened intelligence , would n't the rats soon develop a method for brewing alcohol , thus fixing this problem just like humans do ?</tokentext>
<sentencetext>With their heightened intelligence, wouldn't the rats soon develop a method for brewing alcohol, thus fixing this problem just like humans do?</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964080</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29978498</id>
	<title>The Secret of Nimh?</title>
	<author>Anonymous</author>
	<datestamp>1257005760000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>It's the "Secret of Nimh" all over again</p></htmltext>
<tokenext>It 's the " Secret of Nimh " all over again</tokentext>
<sentencetext>It's the "Secret of Nimh" all over again</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29965054</id>
	<title>Re:Memory is an interesting thing</title>
	<author>ikefox</author>
	<datestamp>1257270900000</datestamp>
	<modclass>Informativ</modclass>
	<modscore>3</modscore>
	<htmltext>Well, the NR2B gene is encoding for a very common and well known receptor within both rat and human brains - the NMDA receptor. These receptors have been the target of the majority of recent studies into working memory and synaptic plasticity, or so-called "long-term potentiation". Basically, the NMDA receptor is the most likely cause of memory reinforcement.

The idea is that when two neurons fire simultaneously, the connection between them is strengthened for a long period of time. That is, the post-synaptic neuron becomes more sensitive to input from the pre-synaptic neuron. This effect is input-specific, in that it is only effective between the two specific neurons involved, and no similar input from other pre-synaptic neurons is necessarily potentiated. Most LTP relies on the NMDA receptors to function, via the calcium ion channels within most synapses. This is why increasing the number of NMDA receptors would likely reflect a quantitative increase in memory.

This isn't exactly breaking news - researchers have known about the NMDA receptors/NR2B gene for years, and I've seen studies from several years ago with the same approximate findings in animal models.</htmltext>
<tokenext>Well , the NR2B gene is encoding for a very common and well known receptor within both rat and human brains - the NMDA receptor .
These receptors have been the target of the majority of recent studies into working memory and synaptic plasticity , or so-called " long-term potentiation " .
Basically , the NMDA receptor is the most likely cause of memory reinforcement .
The idea is that when two neurons fire simultaneously , the connection between them is strengthened for a long period of time .
That is , the post-synaptic neuron becomes more sensitive to input from the pre-synaptic neuron .
This effect is input-specific , in that it is only effective between the two specific neurons involved , and no similar input from other pre-synaptic neurons is necessarily potentiated .
Most LTP relies on the NMDA receptors to function , via the calcium ion channels within most synapses .
This is why increasing the number of NMDA receptors would likely reflect a quantitative increase in memory .
This is n't exactly breaking news - researchers have known about the NMDA receptors/NR2B gene for years , and I 've seen studies from several years ago with the same approximate findings in animal models .</tokentext>
<sentencetext>Well, the NR2B gene is encoding for a very common and well known receptor within both rat and human brains - the NMDA receptor.
These receptors have been the target of the majority of recent studies into working memory and synaptic plasticity, or so-called "long-term potentiation".
Basically, the NMDA receptor is the most likely cause of memory reinforcement.
The idea is that when two neurons fire simultaneously, the connection between them is strengthened for a long period of time.
That is, the post-synaptic neuron becomes more sensitive to input from the pre-synaptic neuron.
This effect is input-specific, in that it is only effective between the two specific neurons involved, and no similar input from other pre-synaptic neurons is necessarily potentiated.
Most LTP relies on the NMDA receptors to function, via the calcium ion channels within most synapses.
This is why increasing the number of NMDA receptors would likely reflect a quantitative increase in memory.
This isn't exactly breaking news - researchers have known about the NMDA receptors/NR2B gene for years, and I've seen studies from several years ago with the same approximate findings in animal models.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963840</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964566</id>
	<title>Re:We already knew it worked for mice</title>
	<author>conspirator57</author>
	<datestamp>1257268920000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>maybe remembering all the crap you did to other rats (or people) to survive (steal their resources) causes depression and reduces liklihood of reproduction.</p><p>We as a society certainly have a selective memory and blinkered recognition of history and current events.</p></htmltext>
<tokenext>maybe remembering all the crap you did to other rats ( or people ) to survive ( steal their resources ) causes depression and reduces liklihood of reproduction.We as a society certainly have a selective memory and blinkered recognition of history and current events .</tokentext>
<sentencetext>maybe remembering all the crap you did to other rats (or people) to survive (steal their resources) causes depression and reduces liklihood of reproduction.We as a society certainly have a selective memory and blinkered recognition of history and current events.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964520</id>
	<title>Re:We already knew it worked for mice</title>
	<author>MattSausage</author>
	<datestamp>1257268740000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext>Well, my understanding of evolution is that it only works on disadvantageous genes. Specifically, a trait has to keep a rat from reproducing, or reproduce less often in order to weed out that trait.

Perhaps the reason this hasn't come up naturally is because there is no pressure exerted on the rat's reproductive cycle if he can't remember as long as some other rat.  Basically, a rat only has to be as smart as necessary to reproduce.  Perhaps there is no advantage to a longer memory, remembering longer simply doesn't get you more tail.</htmltext>
<tokenext>Well , my understanding of evolution is that it only works on disadvantageous genes .
Specifically , a trait has to keep a rat from reproducing , or reproduce less often in order to weed out that trait .
Perhaps the reason this has n't come up naturally is because there is no pressure exerted on the rat 's reproductive cycle if he ca n't remember as long as some other rat .
Basically , a rat only has to be as smart as necessary to reproduce .
Perhaps there is no advantage to a longer memory , remembering longer simply does n't get you more tail .</tokentext>
<sentencetext>Well, my understanding of evolution is that it only works on disadvantageous genes.
Specifically, a trait has to keep a rat from reproducing, or reproduce less often in order to weed out that trait.
Perhaps the reason this hasn't come up naturally is because there is no pressure exerted on the rat's reproductive cycle if he can't remember as long as some other rat.
Basically, a rat only has to be as smart as necessary to reproduce.
Perhaps there is no advantage to a longer memory, remembering longer simply doesn't get you more tail.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963862</id>
	<title>Pinky and the Brain</title>
	<author>BaldNerd</author>
	<datestamp>1257265920000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>It's Pinky and the Brain,
Pinky and the Brain.
One is a genuis
The other's insane.
They're laboratory mice
Their genes have spliced.
NARF!</htmltext>
<tokenext>It 's Pinky and the Brain , Pinky and the Brain .
One is a genuis The other 's insane .
They 're laboratory mice Their genes have spliced .
NARF !</tokentext>
<sentencetext>It's Pinky and the Brain,
Pinky and the Brain.
One is a genuis
The other's insane.
They're laboratory mice
Their genes have spliced.
NARF!</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29973566</id>
	<title>Re:NIMH</title>
	<author>fractoid</author>
	<datestamp>1257270240000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>I came here to say this exact thing. I guess little Timothy will be alright after all.<nobr> <wbr></nobr>:)</htmltext>
<tokenext>I came here to say this exact thing .
I guess little Timothy will be alright after all .
: )</tokentext>
<sentencetext>I came here to say this exact thing.
I guess little Timothy will be alright after all.
:)</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963746</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29964674</id>
	<title>Re:We already knew it worked for mice</title>
	<author>Anonymous</author>
	<datestamp>1257269280000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>Does improved memory necessarily mean improved intelligence? Yes it would be a big help to be able to use more information at once in making decisions, but you still need the ability to synthesize that information into a logical and useful conclusion.</p><p>Would this help us remember the right information? What a rat needs to remember to navigate a maze isn't at all the same as what I need to remember to program. That thought process is very roughly analogous, but not the information required.</p><p>Not to mention, being able to forget is critical to our mental health. Improved memory is useful, but not at the expense of losing our ability to forget. What good is it to remember everything if that means you're permanently paralyzed in fear by a trauma that happened thirty years earlier?</p></htmltext>
<tokenext>Does improved memory necessarily mean improved intelligence ?
Yes it would be a big help to be able to use more information at once in making decisions , but you still need the ability to synthesize that information into a logical and useful conclusion.Would this help us remember the right information ?
What a rat needs to remember to navigate a maze is n't at all the same as what I need to remember to program .
That thought process is very roughly analogous , but not the information required.Not to mention , being able to forget is critical to our mental health .
Improved memory is useful , but not at the expense of losing our ability to forget .
What good is it to remember everything if that means you 're permanently paralyzed in fear by a trauma that happened thirty years earlier ?</tokentext>
<sentencetext>Does improved memory necessarily mean improved intelligence?
Yes it would be a big help to be able to use more information at once in making decisions, but you still need the ability to synthesize that information into a logical and useful conclusion.Would this help us remember the right information?
What a rat needs to remember to navigate a maze isn't at all the same as what I need to remember to program.
That thought process is very roughly analogous, but not the information required.Not to mention, being able to forget is critical to our mental health.
Improved memory is useful, but not at the expense of losing our ability to forget.
What good is it to remember everything if that means you're permanently paralyzed in fear by a trauma that happened thirty years earlier?</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963950</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963952</id>
	<title>repeat story</title>
	<author>nimbius</author>
	<datestamp>1257266340000</datestamp>
	<modclass>Funny</modclass>
	<modscore>2</modscore>
	<htmltext>this has already been done at <a href="http://www.theonion.com/content/news/underfunded\_scientists\_force" title="theonion.com">HLM Laboratories in sonoma, ca</a> [theonion.com]</htmltext>
<tokenext>this has already been done at HLM Laboratories in sonoma , ca [ theonion.com ]</tokentext>
<sentencetext>this has already been done at HLM Laboratories in sonoma, ca [theonion.com]</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963998</id>
	<title>Re:The world needs this....</title>
	<author>Wargames</author>
	<datestamp>1257266580000</datestamp>
	<modclass>Funny</modclass>
	<modscore>2</modscore>
	<htmltext>Did you consider a smarter rat might learn some ratonal hygiene and stop carrying deseases?  Rats would write more ratonal software.</htmltext>
<tokenext>Did you consider a smarter rat might learn some ratonal hygiene and stop carrying deseases ?
Rats would write more ratonal software .</tokentext>
<sentencetext>Did you consider a smarter rat might learn some ratonal hygiene and stop carrying deseases?
Rats would write more ratonal software.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29963814</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_11_03_1450211.29965588</id>
	<title>James Herbert</title>
	<author>slashmojo</author>
	<datestamp>1257273180000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>No good can come of this..</p><p>"For millions of years man and rats had been natural enemies. But now for the first time - suddenly, shockingly, horribly - the balance of power had shifted."<br><a href="http://www.james-herbert.co.uk/rats.htm" title="james-herbert.co.uk">http://www.james-herbert.co.uk/rats.htm</a> [james-herbert.co.uk]</p></htmltext>
<tokenext>No good can come of this.. " For millions of years man and rats had been natural enemies .
But now for the first time - suddenly , shockingly , horribly - the balance of power had shifted .
" http : //www.james-herbert.co.uk/rats.htm [ james-herbert.co.uk ]</tokentext>
<sentencetext>No good can come of this.."For millions of years man and rats had been natural enemies.
But now for the first time - suddenly, shockingly, horribly - the balance of power had shifted.
"http://www.james-herbert.co.uk/rats.htm [james-herbert.co.uk]</sentencetext>
</comment>
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