<article>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#article09_07_02_192249</id>
	<title>HIV/AIDS Vaccine To Begin Phase I Human Trials</title>
	<author>timothy</author>
	<datestamp>1246562460000</datestamp>
	<htmltext>An anonymous reader writes <i>"An HIV/AIDS vaccine developed in Ontario has <a href="http://communications.uwo.ca/com/western\_news/stories/hiv\%10aids\_vaccine\_reaches\_milestone\_20090702444563/">applied for Phase 1 human trials</a>. Safety and immunogenicity studies of the vaccine, dubbed SAV001-H, have already been completed on animals. Phase 1 human trials will check the safety of the vaccine on HIV positive volunteers. Phase 2 will then test immunogenicity."</i></htmltext>
<tokenext>An anonymous reader writes " An HIV/AIDS vaccine developed in Ontario has applied for Phase 1 human trials .
Safety and immunogenicity studies of the vaccine , dubbed SAV001-H , have already been completed on animals .
Phase 1 human trials will check the safety of the vaccine on HIV positive volunteers .
Phase 2 will then test immunogenicity .
"</tokentext>
<sentencetext>An anonymous reader writes "An HIV/AIDS vaccine developed in Ontario has applied for Phase 1 human trials.
Safety and immunogenicity studies of the vaccine, dubbed SAV001-H, have already been completed on animals.
Phase 1 human trials will check the safety of the vaccine on HIV positive volunteers.
Phase 2 will then test immunogenicity.
"</sentencetext>
</article>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562931</id>
	<title>Re:Which is It?</title>
	<author>Anonymous</author>
	<datestamp>1246567260000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>5</modscore>
	<htmltext><blockquote><div><p>HIV/AIDS is stupid</p></div></blockquote><p>
Are you trying to promote the <a href="http://en.wikipedia.org/wiki/AIDS\_denialism" title="wikipedia.org" rel="nofollow">HIV doesn't necessarily cause aids</a> [wikipedia.org] point of view?
<br> <br>
The vaccine in question does as any viral vaccine does, which is to help prevent an exposure to a virus from turning into an infection.  In this case, it is intended to help prevent exposure to HIV from becoming AIDS.  Once exposure has progressed into an infection, vaccines have little, if any, efficacy.</p></div>
	</htmltext>
<tokenext>HIV/AIDS is stupid Are you trying to promote the HIV does n't necessarily cause aids [ wikipedia.org ] point of view ?
The vaccine in question does as any viral vaccine does , which is to help prevent an exposure to a virus from turning into an infection .
In this case , it is intended to help prevent exposure to HIV from becoming AIDS .
Once exposure has progressed into an infection , vaccines have little , if any , efficacy .</tokentext>
<sentencetext>HIV/AIDS is stupid
Are you trying to promote the HIV doesn't necessarily cause aids [wikipedia.org] point of view?
The vaccine in question does as any viral vaccine does, which is to help prevent an exposure to a virus from turning into an infection.
In this case, it is intended to help prevent exposure to HIV from becoming AIDS.
Once exposure has progressed into an infection, vaccines have little, if any, efficacy.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562527</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565647</id>
	<title>Re:Which is It?</title>
	<author>SUB7IME</author>
	<datestamp>1246535280000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>Within the medical world, we routinely talk about HIV/AIDS. The former is the sine qua non for the latter. Preventing the former leads to prevention of the latter. Thus, a successful vaccine will prevent HIV/AIDS.</htmltext>
<tokenext>Within the medical world , we routinely talk about HIV/AIDS .
The former is the sine qua non for the latter .
Preventing the former leads to prevention of the latter .
Thus , a successful vaccine will prevent HIV/AIDS .</tokentext>
<sentencetext>Within the medical world, we routinely talk about HIV/AIDS.
The former is the sine qua non for the latter.
Preventing the former leads to prevention of the latter.
Thus, a successful vaccine will prevent HIV/AIDS.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563149</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563281</id>
	<title>Re:Is this it?</title>
	<author>Opportunist</author>
	<datestamp>1246525200000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>3</modscore>
	<htmltext><p>Could some mod drop some insightful on that post?</p><p>It was pretty much what I was thinking. Vaccine for a highly mutating virus. Good for how long? A day?</p><p>What we should wait for before rejoicing is whether the vaccine is still working a year from now.</p></htmltext>
<tokenext>Could some mod drop some insightful on that post ? It was pretty much what I was thinking .
Vaccine for a highly mutating virus .
Good for how long ?
A day ? What we should wait for before rejoicing is whether the vaccine is still working a year from now .</tokentext>
<sentencetext>Could some mod drop some insightful on that post?It was pretty much what I was thinking.
Vaccine for a highly mutating virus.
Good for how long?
A day?What we should wait for before rejoicing is whether the vaccine is still working a year from now.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562877</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28566797</id>
	<title>Re:Cue objections from the religious right:</title>
	<author>Anonymous</author>
	<datestamp>1246542240000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext>Anon because I moderated.<br> <br>
Bible menions that the world and humans were created, and God's action to do so, but the actual process between when God said something and he saw it was good was never explained.<br> <br>
On of God's most useful creation was evolution IMHO.</htmltext>
<tokenext>Anon because I moderated .
Bible menions that the world and humans were created , and God 's action to do so , but the actual process between when God said something and he saw it was good was never explained .
On of God 's most useful creation was evolution IMHO .</tokentext>
<sentencetext>Anon because I moderated.
Bible menions that the world and humans were created, and God's action to do so, but the actual process between when God said something and he saw it was good was never explained.
On of God's most useful creation was evolution IMHO.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564263</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28566929</id>
	<title>Re:how do you test it?</title>
	<author>fullfactorial</author>
	<datestamp>1246543260000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><div class="quote"><p>Presumably this is a therapeutic vaccine intended to equip the immune system to fight HIV before it trashes your immune system irreparably.</p></div><p> No, it's a preventative vaccine.  They are testing it on HIV positive volunteers to be sure that it doesn't have any serious side effects (like infecting you with real live HIV).</p></div>
	</htmltext>
<tokenext>Presumably this is a therapeutic vaccine intended to equip the immune system to fight HIV before it trashes your immune system irreparably .
No , it 's a preventative vaccine .
They are testing it on HIV positive volunteers to be sure that it does n't have any serious side effects ( like infecting you with real live HIV ) .</tokentext>
<sentencetext>Presumably this is a therapeutic vaccine intended to equip the immune system to fight HIV before it trashes your immune system irreparably.
No, it's a preventative vaccine.
They are testing it on HIV positive volunteers to be sure that it doesn't have any serious side effects (like infecting you with real live HIV).
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563307</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28568243</id>
	<title>Re:Cue objections from the religious right:</title>
	<author>Anonymous</author>
	<datestamp>1246554780000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>Speaking as a life-long Christian with a Master's in theology: No, it doesn't.</p><p>If you stop at the word "created," you're good. The second half of your first sentence may be believed by some Christians, but it is not "clearly stated" anywhere. In fact, the majority of the Christian churches in the world do in fact believe evolution is a fact of history (the Catholic Church being only the biggest and most obvious choice). Christians believe the universe was created in the sense that it was brought about by the Creator, but as to the mechanics of its origin... well, that's why we have the physical sciences.</p></htmltext>
<tokenext>Speaking as a life-long Christian with a Master 's in theology : No , it does n't.If you stop at the word " created , " you 're good .
The second half of your first sentence may be believed by some Christians , but it is not " clearly stated " anywhere .
In fact , the majority of the Christian churches in the world do in fact believe evolution is a fact of history ( the Catholic Church being only the biggest and most obvious choice ) .
Christians believe the universe was created in the sense that it was brought about by the Creator , but as to the mechanics of its origin... well , that 's why we have the physical sciences .</tokentext>
<sentencetext>Speaking as a life-long Christian with a Master's in theology: No, it doesn't.If you stop at the word "created," you're good.
The second half of your first sentence may be believed by some Christians, but it is not "clearly stated" anywhere.
In fact, the majority of the Christian churches in the world do in fact believe evolution is a fact of history (the Catholic Church being only the biggest and most obvious choice).
Christians believe the universe was created in the sense that it was brought about by the Creator, but as to the mechanics of its origin... well, that's why we have the physical sciences.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564263</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565379</id>
	<title>Re:Which is It?</title>
	<author>Anonymous</author>
	<datestamp>1246533720000</datestamp>
	<modclass>Funny</modclass>
	<modscore>2</modscore>
	<htmltext>since this post is 4 insightful, i'm going to assume that having sex with a virgin infant (as opposed to a slutty one) really <i>is</i> going to cure my AIDS.</htmltext>
<tokenext>since this post is 4 insightful , i 'm going to assume that having sex with a virgin infant ( as opposed to a slutty one ) really is going to cure my AIDS .</tokentext>
<sentencetext>since this post is 4 insightful, i'm going to assume that having sex with a virgin infant (as opposed to a slutty one) really is going to cure my AIDS.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562615</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28566359</id>
	<title>Is this it?  Small chance</title>
	<author>Tom DBA</author>
	<datestamp>1246539360000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><a href="http://www.hvtn.org/science/trials.html" title="hvtn.org" rel="nofollow">http://www.hvtn.org/science/trials.html</a> [hvtn.org]  Many trials have come, gone, failed, are in the works.  HIV is very complicated.  Is THIS IT?  Likely this is a low news day or a University of Western Ontario alum day.  Phase I is just to prove people don't die from taking the vaccine.  A far cry from a real, successful vaccine.</p></htmltext>
<tokenext>http : //www.hvtn.org/science/trials.html [ hvtn.org ] Many trials have come , gone , failed , are in the works .
HIV is very complicated .
Is THIS IT ?
Likely this is a low news day or a University of Western Ontario alum day .
Phase I is just to prove people do n't die from taking the vaccine .
A far cry from a real , successful vaccine .</tokentext>
<sentencetext>http://www.hvtn.org/science/trials.html [hvtn.org]  Many trials have come, gone, failed, are in the works.
HIV is very complicated.
Is THIS IT?
Likely this is a low news day or a University of Western Ontario alum day.
Phase I is just to prove people don't die from taking the vaccine.
A far cry from a real, successful vaccine.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562707</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28567913</id>
	<title>Damnit!</title>
	<author>jameshofo</author>
	<datestamp>1246551900000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>Now the only excuse I will have not to be having sex is my social ineptitude!</htmltext>
<tokenext>Now the only excuse I will have not to be having sex is my social ineptitude !</tokentext>
<sentencetext>Now the only excuse I will have not to be having sex is my social ineptitude!</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28567725</id>
	<title>Re:Is this it?</title>
	<author>Baba Ram Dass</author>
	<datestamp>1246549980000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>That would suck if it's the former. If you hate when people bitch about getting the flu after they get the flu shot, just wait...</p></htmltext>
<tokenext>That would suck if it 's the former .
If you hate when people bitch about getting the flu after they get the flu shot , just wait.. .</tokentext>
<sentencetext>That would suck if it's the former.
If you hate when people bitch about getting the flu after they get the flu shot, just wait...</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562877</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28569787</id>
	<title>Re:Test on</title>
	<author>Bacon Bits</author>
	<datestamp>1246618920000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>Animal tests are already complete.  First they do laboratory testing on blood and tissue samples.  Then they do whole animal testing.  Then they test for safety on humans (often testing the drug on completely healthy subjects).  Then they test for efficacy on humans.  Then they test it against other, similar drugs which do the same thing.  In the US, it takes roughly 15 to 20 years to progress through all the tests and analysis required before a drug hits the proverbial shelves.</p></htmltext>
<tokenext>Animal tests are already complete .
First they do laboratory testing on blood and tissue samples .
Then they do whole animal testing .
Then they test for safety on humans ( often testing the drug on completely healthy subjects ) .
Then they test for efficacy on humans .
Then they test it against other , similar drugs which do the same thing .
In the US , it takes roughly 15 to 20 years to progress through all the tests and analysis required before a drug hits the proverbial shelves .</tokentext>
<sentencetext>Animal tests are already complete.
First they do laboratory testing on blood and tissue samples.
Then they do whole animal testing.
Then they test for safety on humans (often testing the drug on completely healthy subjects).
Then they test for efficacy on humans.
Then they test it against other, similar drugs which do the same thing.
In the US, it takes roughly 15 to 20 years to progress through all the tests and analysis required before a drug hits the proverbial shelves.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562583</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563347</id>
	<title>Re:how do you test it?</title>
	<author>Anonymous</author>
	<datestamp>1246525380000</datestamp>
	<modclass>Informativ</modclass>
	<modscore>1</modscore>
	<htmltext><p>No there is no prerequisite like that.</p><p>Here's how the studies typically work.</p><p>1. Locate a country that has an extremely high HIV prevalance (some countries in Africa have 20\% or higher HIV rates)<br>2. Advertise for a few thousand prostitutes and IV drug users and other high risk people to participate (even if some non high risk people come no big deal<nobr> <wbr></nobr>.. because statistically half of them will get he placebo so it will not hurt the study).<br>3. Offer adequate compensation for participation in the study<br>4. Inform each particpatant equally and thoruoghly about the dangers of risky sex<br>5. Stress that being vaccinated may not protect them and that furthermore they may be getting a fake injection (termed a placebo).<br>6. Innoculate half (or whatever) of the participants with the vaccine, the other half get a bogus injection (the placebo).</p><p>Human nature is such that no matter how sincere and good faith your effort was to inform them of the risks of HIV, many of the participants will still go out and have risky sex.</p><p>7. After 1 or 2 years test the participants in the study. If the vacccinated group has significantly less HIV positive people than the ones from the placebo group<nobr> <wbr></nobr>.. you vaccine works. If there is no statistical difference<nobr> <wbr></nobr>.. your vaccine's a dud. If the placebo group has less HIV positive people (like what happened in a recent study)<nobr> <wbr></nobr>.. then yikes your vaccine increases the risk.</p></htmltext>
<tokenext>No there is no prerequisite like that.Here 's how the studies typically work.1 .
Locate a country that has an extremely high HIV prevalance ( some countries in Africa have 20 \ % or higher HIV rates ) 2 .
Advertise for a few thousand prostitutes and IV drug users and other high risk people to participate ( even if some non high risk people come no big deal .. because statistically half of them will get he placebo so it will not hurt the study ) .3 .
Offer adequate compensation for participation in the study4 .
Inform each particpatant equally and thoruoghly about the dangers of risky sex5 .
Stress that being vaccinated may not protect them and that furthermore they may be getting a fake injection ( termed a placebo ) .6 .
Innoculate half ( or whatever ) of the participants with the vaccine , the other half get a bogus injection ( the placebo ) .Human nature is such that no matter how sincere and good faith your effort was to inform them of the risks of HIV , many of the participants will still go out and have risky sex.7 .
After 1 or 2 years test the participants in the study .
If the vacccinated group has significantly less HIV positive people than the ones from the placebo group .. you vaccine works .
If there is no statistical difference .. your vaccine 's a dud .
If the placebo group has less HIV positive people ( like what happened in a recent study ) .. then yikes your vaccine increases the risk .</tokentext>
<sentencetext>No there is no prerequisite like that.Here's how the studies typically work.1.
Locate a country that has an extremely high HIV prevalance (some countries in Africa have 20\% or higher HIV rates)2.
Advertise for a few thousand prostitutes and IV drug users and other high risk people to participate (even if some non high risk people come no big deal .. because statistically half of them will get he placebo so it will not hurt the study).3.
Offer adequate compensation for participation in the study4.
Inform each particpatant equally and thoruoghly about the dangers of risky sex5.
Stress that being vaccinated may not protect them and that furthermore they may be getting a fake injection (termed a placebo).6.
Innoculate half (or whatever) of the participants with the vaccine, the other half get a bogus injection (the placebo).Human nature is such that no matter how sincere and good faith your effort was to inform them of the risks of HIV, many of the participants will still go out and have risky sex.7.
After 1 or 2 years test the participants in the study.
If the vacccinated group has significantly less HIV positive people than the ones from the placebo group .. you vaccine works.
If there is no statistical difference .. your vaccine's a dud.
If the placebo group has less HIV positive people (like what happened in a recent study) .. then yikes your vaccine increases the risk.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562789</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564399</id>
	<title>Re:Cue objections from the religious right:</title>
	<author>mevets</author>
	<datestamp>1246529280000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>4</modscore>
	<htmltext><p>Sorry, it is the rotten millions that spoil it for the good few.</p></htmltext>
<tokenext>Sorry , it is the rotten millions that spoil it for the good few .</tokentext>
<sentencetext>Sorry, it is the rotten millions that spoil it for the good few.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562683</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562725</id>
	<title>Re:Cue objections from the religious right:</title>
	<author>McGregorMortis</author>
	<datestamp>1246566660000</datestamp>
	<modclass>Troll</modclass>
	<modscore>0</modscore>
	<htmltext><p>Ideas like that should be encouraged, as they could be very helpful in ridding the world of the religious right.</p></htmltext>
<tokenext>Ideas like that should be encouraged , as they could be very helpful in ridding the world of the religious right .</tokentext>
<sentencetext>Ideas like that should be encouraged, as they could be very helpful in ridding the world of the religious right.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562581</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28568433</id>
	<title>Re:Is this it?</title>
	<author>Anenome</author>
	<datestamp>1246557000000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>"I assume that depends on the level of immunity it provides. Are we talking Flu Vaccine or Small Pox vaccine level of protection?"</p><p>First of all, even the Smallpox vaccine only lasts for about 5 years before you need a booster shot. Your immune system forgets. Just about everyone in the world would get Smallpox today if it got out. We don't vaccinate for smallpox anymore (foolishly perhaps) because the virus no longer exists in the wild.</p><p>"It was pretty much what I was thinking. Vaccine for a highly mutating virus. Good for how long? A day?<br>What we should wait for before rejoicing is whether the vaccine is still working a year from now."</p><p>Secondly, deeper insights into virology would allay your fear here. There are parts of a virus that mutate rapidly and parts that basically cannot mutate at all, or at least mutate very slowly. This is like the difference between changing clothes everyday and leaving your heart at home. A true and effective vaccine targets the parts of the virus that mutate very slowly.</p><p>There are some seven people in the world genetically immune to HIV. I wonder how much we could learn from their DNA.</p></htmltext>
<tokenext>" I assume that depends on the level of immunity it provides .
Are we talking Flu Vaccine or Small Pox vaccine level of protection ?
" First of all , even the Smallpox vaccine only lasts for about 5 years before you need a booster shot .
Your immune system forgets .
Just about everyone in the world would get Smallpox today if it got out .
We do n't vaccinate for smallpox anymore ( foolishly perhaps ) because the virus no longer exists in the wild .
" It was pretty much what I was thinking .
Vaccine for a highly mutating virus .
Good for how long ?
A day ? What we should wait for before rejoicing is whether the vaccine is still working a year from now .
" Secondly , deeper insights into virology would allay your fear here .
There are parts of a virus that mutate rapidly and parts that basically can not mutate at all , or at least mutate very slowly .
This is like the difference between changing clothes everyday and leaving your heart at home .
A true and effective vaccine targets the parts of the virus that mutate very slowly.There are some seven people in the world genetically immune to HIV .
I wonder how much we could learn from their DNA .</tokentext>
<sentencetext>"I assume that depends on the level of immunity it provides.
Are we talking Flu Vaccine or Small Pox vaccine level of protection?
"First of all, even the Smallpox vaccine only lasts for about 5 years before you need a booster shot.
Your immune system forgets.
Just about everyone in the world would get Smallpox today if it got out.
We don't vaccinate for smallpox anymore (foolishly perhaps) because the virus no longer exists in the wild.
"It was pretty much what I was thinking.
Vaccine for a highly mutating virus.
Good for how long?
A day?What we should wait for before rejoicing is whether the vaccine is still working a year from now.
"Secondly, deeper insights into virology would allay your fear here.
There are parts of a virus that mutate rapidly and parts that basically cannot mutate at all, or at least mutate very slowly.
This is like the difference between changing clothes everyday and leaving your heart at home.
A true and effective vaccine targets the parts of the virus that mutate very slowly.There are some seven people in the world genetically immune to HIV.
I wonder how much we could learn from their DNA.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562877</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563397</id>
	<title>Re:how do you test it?</title>
	<author>Anonymous</author>
	<datestamp>1246525560000</datestamp>
	<modclass>Informativ</modclass>
	<modscore>4</modscore>
	<htmltext>This is a phase one trial, which doesn't test whether it works, it tests whether it is harmful.  The vaccine will be administered to a number of people who already have HIV to see if they have any adverse reaction to it.  Presumably the next phase of the trial will be to give it to some people in high-risk demographics and see whether any of them still manage to contract HIV.  If they do, then the vaccine doesn't work, although if a smaller number of them contract the disease than would be expected to statistically then it may be worth bringing to market anyway.  The final stage will almost certainly involve injecting someone who has been vaccinated with blood from an HIV-positive patient to see whether it really works.</htmltext>
<tokenext>This is a phase one trial , which does n't test whether it works , it tests whether it is harmful .
The vaccine will be administered to a number of people who already have HIV to see if they have any adverse reaction to it .
Presumably the next phase of the trial will be to give it to some people in high-risk demographics and see whether any of them still manage to contract HIV .
If they do , then the vaccine does n't work , although if a smaller number of them contract the disease than would be expected to statistically then it may be worth bringing to market anyway .
The final stage will almost certainly involve injecting someone who has been vaccinated with blood from an HIV-positive patient to see whether it really works .</tokentext>
<sentencetext>This is a phase one trial, which doesn't test whether it works, it tests whether it is harmful.
The vaccine will be administered to a number of people who already have HIV to see if they have any adverse reaction to it.
Presumably the next phase of the trial will be to give it to some people in high-risk demographics and see whether any of them still manage to contract HIV.
If they do, then the vaccine doesn't work, although if a smaller number of them contract the disease than would be expected to statistically then it may be worth bringing to market anyway.
The final stage will almost certainly involve injecting someone who has been vaccinated with blood from an HIV-positive patient to see whether it really works.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562789</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563201</id>
	<title>Re:No Optimism on HIV</title>
	<author>Yold</author>
	<datestamp>1246568100000</datestamp>
	<modclass>Funny</modclass>
	<modscore>4</modscore>
	<htmltext><p>(3) Abstaining/reducing risky sexual behaviors. For slashdotters, this shouldn't be a problem.</p></htmltext>
<tokenext>( 3 ) Abstaining/reducing risky sexual behaviors .
For slashdotters , this should n't be a problem .</tokentext>
<sentencetext>(3) Abstaining/reducing risky sexual behaviors.
For slashdotters, this shouldn't be a problem.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562905</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28574857</id>
	<title>Re:Cue objections from the religious right:</title>
	<author>Voyager529</author>
	<datestamp>1246613760000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>As someone who (presumably) fits the bill for the "religious right", I personally believe that God's ways are higher than our own. Thus, I have trouble believing that God is going to say something to the extent of, "now let me punish {person} by giving him/her HIV...wait, there's a cure...crap, I gotta rethink this now".</htmltext>
<tokenext>As someone who ( presumably ) fits the bill for the " religious right " , I personally believe that God 's ways are higher than our own .
Thus , I have trouble believing that God is going to say something to the extent of , " now let me punish { person } by giving him/her HIV...wait , there 's a cure...crap , I got ta rethink this now " .</tokentext>
<sentencetext>As someone who (presumably) fits the bill for the "religious right", I personally believe that God's ways are higher than our own.
Thus, I have trouble believing that God is going to say something to the extent of, "now let me punish {person} by giving him/her HIV...wait, there's a cure...crap, I gotta rethink this now".</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562581</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28566893</id>
	<title>Re:Hicks</title>
	<author>Anonymous</author>
	<datestamp>1246542900000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>A fine day for enjoying the spread of herpes.</p></htmltext>
<tokenext>A fine day for enjoying the spread of herpes .</tokentext>
<sentencetext>A fine day for enjoying the spread of herpes.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563599</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28568581</id>
	<title>Re:Which is It?</title>
	<author>quadrox</author>
	<datestamp>1246559160000</datestamp>
	<modclass>Informativ</modclass>
	<modscore>2</modscore>
	<htmltext><p>While your statement is technically correct, vaccines can and do help with existing conditions as well:</p><p><a href="http://en.wikipedia.org/wiki/Vaccination" title="wikipedia.org" rel="nofollow">http://en.wikipedia.org/wiki/Vaccination</a> [wikipedia.org]</p><p>"Some modern vaccines are administered after the patient already has contracted a disease, as in the cases of experimental AIDS, cancer and Alzheimer's disease vaccines. Vaccinia given after exposure to smallpox, within the first four days, is reported to attenuate the disease considerably, and vaccination within the first week is known to be beneficial to a degree."</p><p>My father - who is a doctor - has confirmed this to be true. Apparently some infections (not only HIV, any infection) ARE treated with a vaccination, although it is not the only part of the treatment.</p></htmltext>
<tokenext>While your statement is technically correct , vaccines can and do help with existing conditions as well : http : //en.wikipedia.org/wiki/Vaccination [ wikipedia.org ] " Some modern vaccines are administered after the patient already has contracted a disease , as in the cases of experimental AIDS , cancer and Alzheimer 's disease vaccines .
Vaccinia given after exposure to smallpox , within the first four days , is reported to attenuate the disease considerably , and vaccination within the first week is known to be beneficial to a degree .
" My father - who is a doctor - has confirmed this to be true .
Apparently some infections ( not only HIV , any infection ) ARE treated with a vaccination , although it is not the only part of the treatment .</tokentext>
<sentencetext>While your statement is technically correct, vaccines can and do help with existing conditions as well:http://en.wikipedia.org/wiki/Vaccination [wikipedia.org]"Some modern vaccines are administered after the patient already has contracted a disease, as in the cases of experimental AIDS, cancer and Alzheimer's disease vaccines.
Vaccinia given after exposure to smallpox, within the first four days, is reported to attenuate the disease considerably, and vaccination within the first week is known to be beneficial to a degree.
"My father - who is a doctor - has confirmed this to be true.
Apparently some infections (not only HIV, any infection) ARE treated with a vaccination, although it is not the only part of the treatment.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565011</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562885</id>
	<title>Re:Cue objections from the religious right:</title>
	<author>Anonymous</author>
	<datestamp>1246567140000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>But you can't deny there are people out there like that.  Pat Robertson has said something pretty close to that on a number of occasions.</p></htmltext>
<tokenext>But you ca n't deny there are people out there like that .
Pat Robertson has said something pretty close to that on a number of occasions .</tokentext>
<sentencetext>But you can't deny there are people out there like that.
Pat Robertson has said something pretty close to that on a number of occasions.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562683</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28572645</id>
	<title>Re:Which is It?</title>
	<author>Anonymous</author>
	<datestamp>1246641900000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p><div class="quote"><p>Is this a vaccine for the virus, as one with half a brain would assume?</p></div><p>One with more than half would assume it's a vaccine against the virus. HIV is not an endangered species that would need to be vaccinated against our immune system, it does a pretty good job of that itself.</p></div>
	</htmltext>
<tokenext>Is this a vaccine for the virus , as one with half a brain would assume ? One with more than half would assume it 's a vaccine against the virus .
HIV is not an endangered species that would need to be vaccinated against our immune system , it does a pretty good job of that itself .</tokentext>
<sentencetext>Is this a vaccine for the virus, as one with half a brain would assume?One with more than half would assume it's a vaccine against the virus.
HIV is not an endangered species that would need to be vaccinated against our immune system, it does a pretty good job of that itself.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562527</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28567281</id>
	<title>Re:Which is It?</title>
	<author>Anonymous</author>
	<datestamp>1246545600000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>"...your average bear."<br>pun?</p></htmltext>
<tokenext>" ...your average bear .
" pun ?</tokentext>
<sentencetext>"...your average bear.
"pun?</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563145</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562583</id>
	<title>Test on</title>
	<author>Anonymous</author>
	<datestamp>1246566300000</datestamp>
	<modclass>Funny</modclass>
	<modscore>3</modscore>
	<htmltext><p><div class="quote"><p>Phase 1 human trials will check the safety of the vaccine on HIV positive volunteers</p></div><p> Well, at least they're not doing drug trials on animals anymore, better to use those damn AIDS people. Finally good for something

<br> <br><nobr> <wbr></nobr>/Sarcasm</p></div>
	</htmltext>
<tokenext>Phase 1 human trials will check the safety of the vaccine on HIV positive volunteers Well , at least they 're not doing drug trials on animals anymore , better to use those damn AIDS people .
Finally good for something /Sarcasm</tokentext>
<sentencetext>Phase 1 human trials will check the safety of the vaccine on HIV positive volunteers Well, at least they're not doing drug trials on animals anymore, better to use those damn AIDS people.
Finally good for something

  /Sarcasm
	</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562743</id>
	<title>Re:Cue objections from the religious right:</title>
	<author>Attila Dimedici</author>
	<datestamp>1246566660000</datestamp>
	<modclass>Troll</modclass>
	<modscore>1</modscore>
	<htmltext>I'm sorry, who on the religious right has ever expressed sentiments similar to what you are suggesting?</htmltext>
<tokenext>I 'm sorry , who on the religious right has ever expressed sentiments similar to what you are suggesting ?</tokentext>
<sentencetext>I'm sorry, who on the religious right has ever expressed sentiments similar to what you are suggesting?</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562581</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563919</id>
	<title>Re:Cue objections from the religious right:</title>
	<author>Anonymous</author>
	<datestamp>1246527420000</datestamp>
	<modclass>Interestin</modclass>
	<modscore>2</modscore>
	<htmltext><p>"Not all of us conservative Christians are superstitious like you illustrate...."</p><p>Actually, I think you'll find that the definition of your religion REQUIRES superstitious belief.</p></htmltext>
<tokenext>" Not all of us conservative Christians are superstitious like you illustrate.... " Actually , I think you 'll find that the definition of your religion REQUIRES superstitious belief .</tokentext>
<sentencetext>"Not all of us conservative Christians are superstitious like you illustrate...."Actually, I think you'll find that the definition of your religion REQUIRES superstitious belief.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562683</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28571053</id>
	<title>Re:Is this it?</title>
	<author>registrar</author>
	<datestamp>1246632240000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>Smallpox vaccine is not nearly as effective as you might think.  See <a href="http://www.who.int/vaccines/en/smallpox.shtml" title="who.int">http://www.who.int/vaccines/en/smallpox.shtml</a> [who.int]

</p><p>The reasons that smallpox could be eradicated are that there were only a few types, no animal host, and it was a frigging nasty disease, so <i>everyone</i> wanted to eradicated it.</p></htmltext>
<tokenext>Smallpox vaccine is not nearly as effective as you might think .
See http : //www.who.int/vaccines/en/smallpox.shtml [ who.int ] The reasons that smallpox could be eradicated are that there were only a few types , no animal host , and it was a frigging nasty disease , so everyone wanted to eradicated it .</tokentext>
<sentencetext>Smallpox vaccine is not nearly as effective as you might think.
See http://www.who.int/vaccines/en/smallpox.shtml [who.int]

The reasons that smallpox could be eradicated are that there were only a few types, no animal host, and it was a frigging nasty disease, so everyone wanted to eradicated it.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562877</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28569805</id>
	<title>Just as I thought</title>
	<author>Anonymous</author>
	<datestamp>1246619100000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>HERE COME THE ZOMBIES</p></htmltext>
<tokenext>HERE COME THE ZOMBIES</tokentext>
<sentencetext>HERE COME THE ZOMBIES</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563247</id>
	<title>Re:how do you test it?</title>
	<author>Anonymous</author>
	<datestamp>1246568280000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>I think that it would depend a great deal on your wife.  Where was she last night?  Maybe this is a question you should spend some time pondering...</p></htmltext>
<tokenext>I think that it would depend a great deal on your wife .
Where was she last night ?
Maybe this is a question you should spend some time pondering.. .</tokentext>
<sentencetext>I think that it would depend a great deal on your wife.
Where was she last night?
Maybe this is a question you should spend some time pondering...</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562789</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28566703</id>
	<title>Re:Which is It?</title>
	<author>unifyingtheory</author>
	<datestamp>1246541460000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>2</modscore>
	<htmltext>Surely you realize AIDS is a progression of HIV. So naturally if you get the vaccine prior to HIV exposure you cannot get AIDS, assuming the vaccine works of course.  Thus the vaccine does protect against both (in a unexposed host).<br> <br>
Similarly we have the "flu vaccine".  We don't bother listing all the viruses that cause the flu because they don't really matter; the disease is the important part.  HIV by itself never killed anyone.</htmltext>
<tokenext>Surely you realize AIDS is a progression of HIV .
So naturally if you get the vaccine prior to HIV exposure you can not get AIDS , assuming the vaccine works of course .
Thus the vaccine does protect against both ( in a unexposed host ) .
Similarly we have the " flu vaccine " .
We do n't bother listing all the viruses that cause the flu because they do n't really matter ; the disease is the important part .
HIV by itself never killed anyone .</tokentext>
<sentencetext>Surely you realize AIDS is a progression of HIV.
So naturally if you get the vaccine prior to HIV exposure you cannot get AIDS, assuming the vaccine works of course.
Thus the vaccine does protect against both (in a unexposed host).
Similarly we have the "flu vaccine".
We don't bother listing all the viruses that cause the flu because they don't really matter; the disease is the important part.
HIV by itself never killed anyone.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563149</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28569109</id>
	<title>Re:Is this it?</title>
	<author>Anonymous</author>
	<datestamp>1246653060000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>re 7: in humans HIV only infects T helper cells and macrophages. These cells don't express gap junctions.</p></htmltext>
<tokenext>re 7 : in humans HIV only infects T helper cells and macrophages .
These cells do n't express gap junctions .</tokentext>
<sentencetext>re 7: in humans HIV only infects T helper cells and macrophages.
These cells don't express gap junctions.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565281</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28574335</id>
	<title>Re:No Optimism on HIV</title>
	<author>Anonymous</author>
	<datestamp>1246653060000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p><div class="quote"><p>(3) Abstaining/reducing risky sexual behaviors. For slashdotters, this shouldn't be a problem.</p></div><p>Actually, this would be a worrying factor. Using the Internet for their sexual needs, and their female "status quo" sexual organ: the palm of the hand, slashdotters may have a reduced exposure to this, statistically, but this also means that they'll easily overrule and common sense when they're being offered a real woman, as it's a one in a life time opportunity. This is common deprivation response.</p></div>
	</htmltext>
<tokenext>( 3 ) Abstaining/reducing risky sexual behaviors .
For slashdotters , this should n't be a problem.Actually , this would be a worrying factor .
Using the Internet for their sexual needs , and their female " status quo " sexual organ : the palm of the hand , slashdotters may have a reduced exposure to this , statistically , but this also means that they 'll easily overrule and common sense when they 're being offered a real woman , as it 's a one in a life time opportunity .
This is common deprivation response .</tokentext>
<sentencetext>(3) Abstaining/reducing risky sexual behaviors.
For slashdotters, this shouldn't be a problem.Actually, this would be a worrying factor.
Using the Internet for their sexual needs, and their female "status quo" sexual organ: the palm of the hand, slashdotters may have a reduced exposure to this, statistically, but this also means that they'll easily overrule and common sense when they're being offered a real woman, as it's a one in a life time opportunity.
This is common deprivation response.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563201</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563223</id>
	<title>Re:how do you test it?</title>
	<author>Anonymous</author>
	<datestamp>1246568160000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p><i>If I take the vaccine and I only sleep with my wife and in 10 years I'm HIV free does it work?</i></p><p>It depends on who your wife is screwing.</p></htmltext>
<tokenext>If I take the vaccine and I only sleep with my wife and in 10 years I 'm HIV free does it work ? It depends on who your wife is screwing .</tokentext>
<sentencetext>If I take the vaccine and I only sleep with my wife and in 10 years I'm HIV free does it work?It depends on who your wife is screwing.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562789</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28710099</id>
	<title>so basically</title>
	<author>ClintJCL</author>
	<datestamp>1247660760000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>So basically, you get to cherry pick and selectively believe what you want from a book that was supposedly written by an all-knowing God? Hell, I could probably cherry pick stuff out of Scientology and end up with a sane set of beliefs. But I'd still be a mislead sheep.</htmltext>
<tokenext>So basically , you get to cherry pick and selectively believe what you want from a book that was supposedly written by an all-knowing God ?
Hell , I could probably cherry pick stuff out of Scientology and end up with a sane set of beliefs .
But I 'd still be a mislead sheep .</tokentext>
<sentencetext>So basically, you get to cherry pick and selectively believe what you want from a book that was supposedly written by an all-knowing God?
Hell, I could probably cherry pick stuff out of Scientology and end up with a sane set of beliefs.
But I'd still be a mislead sheep.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562683</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562873</id>
	<title>Re:Is this it?</title>
	<author>BlueBoxSW.com</author>
	<datestamp>1246567080000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>5</modscore>
	<htmltext><p>Phase I is really too early to get any hope up. Most "promising" drugs that enter Phase I don't make it to the end of Phase III (FDA approval).</p></htmltext>
<tokenext>Phase I is really too early to get any hope up .
Most " promising " drugs that enter Phase I do n't make it to the end of Phase III ( FDA approval ) .</tokentext>
<sentencetext>Phase I is really too early to get any hope up.
Most "promising" drugs that enter Phase I don't make it to the end of Phase III (FDA approval).</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562707</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563765</id>
	<title>Re:Which is It?</title>
	<author>sound+vision</author>
	<datestamp>1246526760000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext>"HIV/AIDS" is like "GNU/Linux". Simply unnecessary specificity.</htmltext>
<tokenext>" HIV/AIDS " is like " GNU/Linux " .
Simply unnecessary specificity .</tokentext>
<sentencetext>"HIV/AIDS" is like "GNU/Linux".
Simply unnecessary specificity.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562527</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564529</id>
	<title>This isn't very significant.</title>
	<author>Anonymous</author>
	<datestamp>1246529940000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>Phase 1 is a basic safety check.  It does NOT check if it works.  And we've had many phase 1 HIV vaccine tests.  The problem is most either fail phase 1 (is it safe) or phase 2 (could it work).  If I recall correctly only VAXGEN's AIDSVAX has made it to phase 3 (does it work) and it failed there.  Another phase 1 test doesn't mean we're close...  And yes I worked on HIV vaccines in college as a lab slave/assistant.</p></htmltext>
<tokenext>Phase 1 is a basic safety check .
It does NOT check if it works .
And we 've had many phase 1 HIV vaccine tests .
The problem is most either fail phase 1 ( is it safe ) or phase 2 ( could it work ) .
If I recall correctly only VAXGEN 's AIDSVAX has made it to phase 3 ( does it work ) and it failed there .
Another phase 1 test does n't mean we 're close... And yes I worked on HIV vaccines in college as a lab slave/assistant .</tokentext>
<sentencetext>Phase 1 is a basic safety check.
It does NOT check if it works.
And we've had many phase 1 HIV vaccine tests.
The problem is most either fail phase 1 (is it safe) or phase 2 (could it work).
If I recall correctly only VAXGEN's AIDSVAX has made it to phase 3 (does it work) and it failed there.
Another phase 1 test doesn't mean we're close...  And yes I worked on HIV vaccines in college as a lab slave/assistant.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28567251</id>
	<title>Re:Which is It?</title>
	<author>TheRealMindChild</author>
	<datestamp>1246545420000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>AIDS is a symptom of HIV. Of course they are going to be talked about together. That's like not talking about a cough when you have a cold.</htmltext>
<tokenext>AIDS is a symptom of HIV .
Of course they are going to be talked about together .
That 's like not talking about a cough when you have a cold .</tokentext>
<sentencetext>AIDS is a symptom of HIV.
Of course they are going to be talked about together.
That's like not talking about a cough when you have a cold.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563149</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563149</id>
	<title>Re:Which is It?</title>
	<author>Anonymous</author>
	<datestamp>1246567920000</datestamp>
	<modclass>Redundant</modclass>
	<modscore>1</modscore>
	<htmltext><p>Did anyone read my post, or my own reply?<br>No, guess not.<br>And no one will read this.</p><p>I KNOW THAT THIS IS FOR HIV.<br>MY BEEF IS THE USE OF "HIV/AIDS" IN THE HEADLINE.</p></htmltext>
<tokenext>Did anyone read my post , or my own reply ? No , guess not.And no one will read this.I KNOW THAT THIS IS FOR HIV.MY BEEF IS THE USE OF " HIV/AIDS " IN THE HEADLINE .</tokentext>
<sentencetext>Did anyone read my post, or my own reply?No, guess not.And no one will read this.I KNOW THAT THIS IS FOR HIV.MY BEEF IS THE USE OF "HIV/AIDS" IN THE HEADLINE.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562527</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563335</id>
	<title>Re:how do you test it?</title>
	<author>CanadianRealist</author>
	<datestamp>1246525380000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>They give the vaccine to people in high risk groups. Over time they watch to see if the rate of infection ends up being less than the rate in other people in the same group, who were not vaccinated.</p><p>Deliberately infection someone with a fatal disease, to test a vaccine that you are not sure is effective (hence the need for the test) sounds like criminal negligence, on top of violating the Hippocratic Oath.</p></htmltext>
<tokenext>They give the vaccine to people in high risk groups .
Over time they watch to see if the rate of infection ends up being less than the rate in other people in the same group , who were not vaccinated.Deliberately infection someone with a fatal disease , to test a vaccine that you are not sure is effective ( hence the need for the test ) sounds like criminal negligence , on top of violating the Hippocratic Oath .</tokentext>
<sentencetext>They give the vaccine to people in high risk groups.
Over time they watch to see if the rate of infection ends up being less than the rate in other people in the same group, who were not vaccinated.Deliberately infection someone with a fatal disease, to test a vaccine that you are not sure is effective (hence the need for the test) sounds like criminal negligence, on top of violating the Hippocratic Oath.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562789</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562971</id>
	<title>Re:Cue objections from the religious right:</title>
	<author>RelaxedTension</author>
	<datestamp>1246567380000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>2</modscore>
	<htmltext><p><div class="quote"><p>People want to believe that the stereotype is real though, and you don't help the situation.</p></div><p>
Conservative christians are doing just fine at reinforcing that stereotype by themselves. <a href="http://www.examiner.com/x-10853-Seattle-Humanist-Examiner~y2009m7d1-Oklahoma-Morality-Proclamation-blames-gays-porn-abortion-for-economic-woe" title="examiner.com">Oklahoma-Morality-Proclamation-blames-gays-porn-abortion-for-economic-woe</a> [examiner.com]</p></div>
	</htmltext>
<tokenext>People want to believe that the stereotype is real though , and you do n't help the situation .
Conservative christians are doing just fine at reinforcing that stereotype by themselves .
Oklahoma-Morality-Proclamation-blames-gays-porn-abortion-for-economic-woe [ examiner.com ]</tokentext>
<sentencetext>People want to believe that the stereotype is real though, and you don't help the situation.
Conservative christians are doing just fine at reinforcing that stereotype by themselves.
Oklahoma-Morality-Proclamation-blames-gays-porn-abortion-for-economic-woe [examiner.com]
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562683</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563607</id>
	<title>Who is nuts enough to test effectiveness?</title>
	<author>gubers33</author>
	<datestamp>1246526220000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>I want to know what crazy bastards are volunteering for Phase II and Phase III testing.</htmltext>
<tokenext>I want to know what crazy bastards are volunteering for Phase II and Phase III testing .</tokentext>
<sentencetext>I want to know what crazy bastards are volunteering for Phase II and Phase III testing.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28566529</id>
	<title>Re:how do you test it?</title>
	<author>thesandtiger</author>
	<datestamp>1246540320000</datestamp>
	<modclass>Informativ</modclass>
	<modscore>2</modscore>
	<htmltext><p>One of the studies we're doing in my lab is an intervention with (currently) HIV- youth who engage in frequent risk behaviors (most are sex workers, a little under a third are IV drug users, a very small portion just have risky sex because that's what they do). As part of the study, we do HIV testing every 3 months. We have an "expected" rate of conversion (obtained from other studies) and then we compare our actual rate of conversion to see whether our intervention is having an impact. While I'm no biostatician, I imagine the process is similar for a vaccine trial as for an educational intervention - you get people who are extremely likely to convert, vaccinate them, and if fewer convert (hopefully none of them!) despite engaging in risky activities, you can say that there's very likely been an effect.</p></htmltext>
<tokenext>One of the studies we 're doing in my lab is an intervention with ( currently ) HIV- youth who engage in frequent risk behaviors ( most are sex workers , a little under a third are IV drug users , a very small portion just have risky sex because that 's what they do ) .
As part of the study , we do HIV testing every 3 months .
We have an " expected " rate of conversion ( obtained from other studies ) and then we compare our actual rate of conversion to see whether our intervention is having an impact .
While I 'm no biostatician , I imagine the process is similar for a vaccine trial as for an educational intervention - you get people who are extremely likely to convert , vaccinate them , and if fewer convert ( hopefully none of them !
) despite engaging in risky activities , you can say that there 's very likely been an effect .</tokentext>
<sentencetext>One of the studies we're doing in my lab is an intervention with (currently) HIV- youth who engage in frequent risk behaviors (most are sex workers, a little under a third are IV drug users, a very small portion just have risky sex because that's what they do).
As part of the study, we do HIV testing every 3 months.
We have an "expected" rate of conversion (obtained from other studies) and then we compare our actual rate of conversion to see whether our intervention is having an impact.
While I'm no biostatician, I imagine the process is similar for a vaccine trial as for an educational intervention - you get people who are extremely likely to convert, vaccinate them, and if fewer convert (hopefully none of them!
) despite engaging in risky activities, you can say that there's very likely been an effect.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563307</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565013</id>
	<title>Uganda &amp; Kenya</title>
	<author>vondo</author>
	<datestamp>1246531860000</datestamp>
	<modclass>None</modclass>
	<modscore>2</modscore>
	<htmltext><p>When the article says "Some parts of Kenya" that means the good parts. The overall infection rate in 2003 was estimated at 6.7\%. Uganda is the birthplace, as I recall, of the ABC strategy.</p><p>This article makes it sound as if DC is as bad as "Africa" when it comes to AIDS. Unfortunately (for most of sub-Sahara Africa, not DC residents), this just isn't true.</p><p>3\% may be bad, but 3\% with decent health care is a world away from the 15+\% infection rate and poor health systems that some countries are dealing with.</p></htmltext>
<tokenext>When the article says " Some parts of Kenya " that means the good parts .
The overall infection rate in 2003 was estimated at 6.7 \ % .
Uganda is the birthplace , as I recall , of the ABC strategy.This article makes it sound as if DC is as bad as " Africa " when it comes to AIDS .
Unfortunately ( for most of sub-Sahara Africa , not DC residents ) , this just is n't true.3 \ % may be bad , but 3 \ % with decent health care is a world away from the 15 + \ % infection rate and poor health systems that some countries are dealing with .</tokentext>
<sentencetext>When the article says "Some parts of Kenya" that means the good parts.
The overall infection rate in 2003 was estimated at 6.7\%.
Uganda is the birthplace, as I recall, of the ABC strategy.This article makes it sound as if DC is as bad as "Africa" when it comes to AIDS.
Unfortunately (for most of sub-Sahara Africa, not DC residents), this just isn't true.3\% may be bad, but 3\% with decent health care is a world away from the 15+\% infection rate and poor health systems that some countries are dealing with.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562905</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563651</id>
	<title>Re:No Optimism on HIV</title>
	<author>petrus4</author>
	<datestamp>1246526340000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><i>(3) Abstaining/reducing risky sexual behaviors. For slashdotters, this shouldn't be a problem.</i></p><p>a)  Use condoms/spermicides etc.</p><p>b)  If you're going to be in more than a one night stand with someone, (which is preferable, from a disease point of view) then at least see if they'd be willing to get tested; <i>especially</i> if they've previously engaged in bisexual activity.  It might not be politically correct to say it, but outside of the Third World, HIV <i>is</i> a primarily gay or bi disease.  Call me a bigot for that as much as you want, and then once you've finished, go and look up the statistics.</p><p>c)  Don't go near the ass.  No anal sex, no analingus, and none of the other related activities, either.  In sexual terms, HIV's primary means of transmission/propogation are either anal sex or anal/oral contact.</p><p>d)  If you need blood work or transfusions done, find out what the hygeine policies of the place in question are, in advance.</p><p>e)  Realise that abstinence will not kill you, and that consequently, contrary to popular perception, sex <i>is</i> actually a want, rather than a need.</p></htmltext>
<tokenext>( 3 ) Abstaining/reducing risky sexual behaviors .
For slashdotters , this should n't be a problem.a ) Use condoms/spermicides etc.b ) If you 're going to be in more than a one night stand with someone , ( which is preferable , from a disease point of view ) then at least see if they 'd be willing to get tested ; especially if they 've previously engaged in bisexual activity .
It might not be politically correct to say it , but outside of the Third World , HIV is a primarily gay or bi disease .
Call me a bigot for that as much as you want , and then once you 've finished , go and look up the statistics.c ) Do n't go near the ass .
No anal sex , no analingus , and none of the other related activities , either .
In sexual terms , HIV 's primary means of transmission/propogation are either anal sex or anal/oral contact.d ) If you need blood work or transfusions done , find out what the hygeine policies of the place in question are , in advance.e ) Realise that abstinence will not kill you , and that consequently , contrary to popular perception , sex is actually a want , rather than a need .</tokentext>
<sentencetext>(3) Abstaining/reducing risky sexual behaviors.
For slashdotters, this shouldn't be a problem.a)  Use condoms/spermicides etc.b)  If you're going to be in more than a one night stand with someone, (which is preferable, from a disease point of view) then at least see if they'd be willing to get tested; especially if they've previously engaged in bisexual activity.
It might not be politically correct to say it, but outside of the Third World, HIV is a primarily gay or bi disease.
Call me a bigot for that as much as you want, and then once you've finished, go and look up the statistics.c)  Don't go near the ass.
No anal sex, no analingus, and none of the other related activities, either.
In sexual terms, HIV's primary means of transmission/propogation are either anal sex or anal/oral contact.d)  If you need blood work or transfusions done, find out what the hygeine policies of the place in question are, in advance.e)  Realise that abstinence will not kill you, and that consequently, contrary to popular perception, sex is actually a want, rather than a need.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563201</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565381</id>
	<title>Which "Europeans", reporter? That's a BIG area!</title>
	<author>Anonymous</author>
	<datestamp>1246533780000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><div class="quote"><p><b>" As for point #2, a small percentage of Europeans have a cellular mutation that prevents HIV infection."</b> - by reporter (666905) on Thursday July 02, @03:40PM (#28562905)</p></div><p>See my subject-line above:</p><p><b>Reporter</b> -  Can you tell me (heck, ALL of us) which European nation (or if need be, which 'tribe') does? I am curious, as I am of European descent, &amp; it would be nice to know I can't catch what has killed a few people I knew over time, just by "luck of the genetic draw", because I am clean of this lunacy, but it hasn't been easy for me to stay that way (abstinence BLOWS, lol)... because to be honest with you?</p><p>Well - I don't know about the rest of you, but imo @ least? Well - LOL, I am truly TIRED of celebacy!</p><p>(This is great news though, &amp; I hope it works for EVERYONE on this planet actually - only part that "spooks me", is that the FDA is an agency composed of men, &amp; men? Men can be "bought off", sadly... and, it would be a shame if that were to happen, what with "there is more money in prevention than the cure" from a major pharmaceutical companies' viewpoint)</p><p>Anyhow/anyway:  Thanks!</p><p>Sincerely,</p><p>APK</p><p>P.S.=&gt; Barring myself possibly being "immune" (doubt it), it'd be nice to know which girls (germanic, slavic, etc. et al, if you have to be "generic" about it, nice if it was "specific" to a nationality though) are "Free &amp; Clean" or @ least have a much better shot @ it is all... apk</p></div>
	</htmltext>
<tokenext>" As for point # 2 , a small percentage of Europeans have a cellular mutation that prevents HIV infection .
" - by reporter ( 666905 ) on Thursday July 02 , @ 03 : 40PM ( # 28562905 ) See my subject-line above : Reporter - Can you tell me ( heck , ALL of us ) which European nation ( or if need be , which 'tribe ' ) does ?
I am curious , as I am of European descent , &amp; it would be nice to know I ca n't catch what has killed a few people I knew over time , just by " luck of the genetic draw " , because I am clean of this lunacy , but it has n't been easy for me to stay that way ( abstinence BLOWS , lol ) ... because to be honest with you ? Well - I do n't know about the rest of you , but imo @ least ?
Well - LOL , I am truly TIRED of celebacy !
( This is great news though , &amp; I hope it works for EVERYONE on this planet actually - only part that " spooks me " , is that the FDA is an agency composed of men , &amp; men ?
Men can be " bought off " , sadly... and , it would be a shame if that were to happen , what with " there is more money in prevention than the cure " from a major pharmaceutical companies ' viewpoint ) Anyhow/anyway : Thanks ! Sincerely,APKP.S. = &gt; Barring myself possibly being " immune " ( doubt it ) , it 'd be nice to know which girls ( germanic , slavic , etc .
et al , if you have to be " generic " about it , nice if it was " specific " to a nationality though ) are " Free &amp; Clean " or @ least have a much better shot @ it is all... apk</tokentext>
<sentencetext>" As for point #2, a small percentage of Europeans have a cellular mutation that prevents HIV infection.
" - by reporter (666905) on Thursday July 02, @03:40PM (#28562905)See my subject-line above:Reporter -  Can you tell me (heck, ALL of us) which European nation (or if need be, which 'tribe') does?
I am curious, as I am of European descent, &amp; it would be nice to know I can't catch what has killed a few people I knew over time, just by "luck of the genetic draw", because I am clean of this lunacy, but it hasn't been easy for me to stay that way (abstinence BLOWS, lol)... because to be honest with you?Well - I don't know about the rest of you, but imo @ least?
Well - LOL, I am truly TIRED of celebacy!
(This is great news though, &amp; I hope it works for EVERYONE on this planet actually - only part that "spooks me", is that the FDA is an agency composed of men, &amp; men?
Men can be "bought off", sadly... and, it would be a shame if that were to happen, what with "there is more money in prevention than the cure" from a major pharmaceutical companies' viewpoint)Anyhow/anyway:  Thanks!Sincerely,APKP.S.=&gt; Barring myself possibly being "immune" (doubt it), it'd be nice to know which girls (germanic, slavic, etc.
et al, if you have to be "generic" about it, nice if it was "specific" to a nationality though) are "Free &amp; Clean" or @ least have a much better shot @ it is all... apk
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562905</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28566595</id>
	<title>Re:Test: How?</title>
	<author>Tom DBA</author>
	<datestamp>1246540740000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>3</modscore>
	<htmltext><p>Actually, there are tons of people available for the Phase II and III trials.  There's a whole generation of young gays who are catching HIV left and right because they don't use protection.</p></htmltext>
<tokenext>Actually , there are tons of people available for the Phase II and III trials .
There 's a whole generation of young gays who are catching HIV left and right because they do n't use protection .</tokentext>
<sentencetext>Actually, there are tons of people available for the Phase II and III trials.
There's a whole generation of young gays who are catching HIV left and right because they don't use protection.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563773</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28566645</id>
	<title>A great Boon for anyone in the medical field!</title>
	<author>jameskojiro</author>
	<datestamp>1246541040000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>3</modscore>
	<htmltext><p>Now they won't have to worry about catching aids from trauma patients if a glove fails or if they accidentally nick themselves in the O.R. while working on a AIDS patient.</p><p>This should help lower the cost of Healthcare as Doctors may need slightly less hazard insurance once inoculated.</p></htmltext>
<tokenext>Now they wo n't have to worry about catching aids from trauma patients if a glove fails or if they accidentally nick themselves in the O.R .
while working on a AIDS patient.This should help lower the cost of Healthcare as Doctors may need slightly less hazard insurance once inoculated .</tokentext>
<sentencetext>Now they won't have to worry about catching aids from trauma patients if a glove fails or if they accidentally nick themselves in the O.R.
while working on a AIDS patient.This should help lower the cost of Healthcare as Doctors may need slightly less hazard insurance once inoculated.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28567793</id>
	<title>Re:Which is It?</title>
	<author>Anonymous</author>
	<datestamp>1246550820000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>Wait, if it has to be a virgin, why is gang-rape involved?  Wouldn't that by definition not work after the first one?</p></htmltext>
<tokenext>Wait , if it has to be a virgin , why is gang-rape involved ?
Would n't that by definition not work after the first one ?</tokentext>
<sentencetext>Wait, if it has to be a virgin, why is gang-rape involved?
Wouldn't that by definition not work after the first one?</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563453</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28569297</id>
	<title>Re:Is this it?</title>
	<author>Japie\_H</author>
	<datestamp>1246612200000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>That depends on whether it is of human origin or not. If there are animal carriers it will not disappear. But the number of infected people <br>
(especially in countries where the animal carrier does not live) will drop drastically.<br> <br>

There is however another risk and that is recklessness, if the chance of getting HIV gets very low (or lower, if you live in the western<br>
 world and look at the infection rate) there is a danger that people will stop being<br>
carefull. There are already reports that people are taking less care because of improved treatment.<br> <br>

Furthermore as others pointed out this is just a Phase I trail, just to see whether you can actually administer the drug<br>
in therapeutic dosages to patients without killing them and to assess parameters like the half life etc.</htmltext>
<tokenext>That depends on whether it is of human origin or not .
If there are animal carriers it will not disappear .
But the number of infected people ( especially in countries where the animal carrier does not live ) will drop drastically .
There is however another risk and that is recklessness , if the chance of getting HIV gets very low ( or lower , if you live in the western world and look at the infection rate ) there is a danger that people will stop being carefull .
There are already reports that people are taking less care because of improved treatment .
Furthermore as others pointed out this is just a Phase I trail , just to see whether you can actually administer the drug in therapeutic dosages to patients without killing them and to assess parameters like the half life etc .</tokentext>
<sentencetext>That depends on whether it is of human origin or not.
If there are animal carriers it will not disappear.
But the number of infected people 
(especially in countries where the animal carrier does not live) will drop drastically.
There is however another risk and that is recklessness, if the chance of getting HIV gets very low (or lower, if you live in the western
 world and look at the infection rate) there is a danger that people will stop being
carefull.
There are already reports that people are taking less care because of improved treatment.
Furthermore as others pointed out this is just a Phase I trail, just to see whether you can actually administer the drug
in therapeutic dosages to patients without killing them and to assess parameters like the half life etc.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564107</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28570375</id>
	<title>Re:Cue objections from the religious right:</title>
	<author>Anonymous</author>
	<datestamp>1246627320000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>You might want to check on Dick Cheney, he wanted to let you know you're kicked out of both Conservatism and Christianity for being OK with gays and believing in evolution.  You're one of those hated moderates that are bringing down the republican part, ya know.</p></htmltext>
<tokenext>You might want to check on Dick Cheney , he wanted to let you know you 're kicked out of both Conservatism and Christianity for being OK with gays and believing in evolution .
You 're one of those hated moderates that are bringing down the republican part , ya know .</tokentext>
<sentencetext>You might want to check on Dick Cheney, he wanted to let you know you're kicked out of both Conservatism and Christianity for being OK with gays and believing in evolution.
You're one of those hated moderates that are bringing down the republican part, ya know.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562683</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28574027</id>
	<title>Re:Is this it?</title>
	<author>celtic\_hackr</author>
	<datestamp>1246650780000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>Yeah, just like Gonorrhea and Syphilis have disappeared<nobr> <wbr></nobr>...<br> <br>
oh, that's right, they're still around.</htmltext>
<tokenext>Yeah , just like Gonorrhea and Syphilis have disappeared .. . oh , that 's right , they 're still around .</tokentext>
<sentencetext>Yeah, just like Gonorrhea and Syphilis have disappeared ... 
oh, that's right, they're still around.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564107</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564107</id>
	<title>Re:Is this it?</title>
	<author>rumblin'rabbit</author>
	<datestamp>1246528140000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>5</modscore>
	<htmltext>It wouldn't have to be 100\% effective to eradicate HIV. Slowing the spread of a disease can be enough to make it (eventually) disappear.</htmltext>
<tokenext>It would n't have to be 100 \ % effective to eradicate HIV .
Slowing the spread of a disease can be enough to make it ( eventually ) disappear .</tokentext>
<sentencetext>It wouldn't have to be 100\% effective to eradicate HIV.
Slowing the spread of a disease can be enough to make it (eventually) disappear.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562877</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28569635</id>
	<title>I hope I am wrong but</title>
	<author>Chrisq</author>
	<datestamp>1246616580000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>I hope I am wrong but this is probably more informative than troll. After all the have already <a href="http://www.politicalaffairs.net/article/articleview/3551/" title="politicalaffairs.net">objected to the HPV vaccine</a> [politicalaffairs.net] and prevent distribution of condoms in areas with high HIV rates. I suspect we <i>will</i> hear objections from the religious right.</htmltext>
<tokenext>I hope I am wrong but this is probably more informative than troll .
After all the have already objected to the HPV vaccine [ politicalaffairs.net ] and prevent distribution of condoms in areas with high HIV rates .
I suspect we will hear objections from the religious right .</tokentext>
<sentencetext>I hope I am wrong but this is probably more informative than troll.
After all the have already objected to the HPV vaccine [politicalaffairs.net] and prevent distribution of condoms in areas with high HIV rates.
I suspect we will hear objections from the religious right.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562581</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562581</id>
	<title>Cue objections from the religious right:</title>
	<author>Anonymous</author>
	<datestamp>1246566300000</datestamp>
	<modclass>Troll</modclass>
	<modscore>-1</modscore>
	<htmltext>AIDS is a form of divine wrath; punishment for the fornicators. Using science to cure AIDS is an evil, godless pursuit.</htmltext>
<tokenext>AIDS is a form of divine wrath ; punishment for the fornicators .
Using science to cure AIDS is an evil , godless pursuit .</tokentext>
<sentencetext>AIDS is a form of divine wrath; punishment for the fornicators.
Using science to cure AIDS is an evil, godless pursuit.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28571337</id>
	<title>Re:Hicks</title>
	<author>Anonymous</author>
	<datestamp>1246634100000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>"Then they came out with herpes, you keep that shit forever like luggage" --Eddie Murphy</p></htmltext>
<tokenext>" Then they came out with herpes , you keep that shit forever like luggage " --Eddie Murphy</tokentext>
<sentencetext>"Then they came out with herpes, you keep that shit forever like luggage" --Eddie Murphy</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565247</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564829</id>
	<title>Re:how do you test it?</title>
	<author>bugnuts</author>
	<datestamp>1246531140000</datestamp>
	<modclass>Informativ</modclass>
	<modscore>2</modscore>
	<htmltext><p><div class="quote"><p>If I take the vaccine and I only sleep with my wife and in 10 years I'm HIV free does it work?<br>Or is one of the pre-requisites of joining the trial that you commit to sleeping with as many sleeezy whores as you can find?</p></div><p>Wouldn't that also depend on how sleazy of a whore your wife is over those 10 years?</p></div>
	</htmltext>
<tokenext>If I take the vaccine and I only sleep with my wife and in 10 years I 'm HIV free does it work ? Or is one of the pre-requisites of joining the trial that you commit to sleeping with as many sleeezy whores as you can find ? Would n't that also depend on how sleazy of a whore your wife is over those 10 years ?</tokentext>
<sentencetext>If I take the vaccine and I only sleep with my wife and in 10 years I'm HIV free does it work?Or is one of the pre-requisites of joining the trial that you commit to sleeping with as many sleeezy whores as you can find?Wouldn't that also depend on how sleazy of a whore your wife is over those 10 years?
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562789</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565419</id>
	<title>Re:Hicks</title>
	<author>martas</author>
	<datestamp>1246534020000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>and a syphilis epidemic shall follow.<br> <br>

bummer, AIDS isn't the only STD. (don't you just looove acronyms?)</htmltext>
<tokenext>and a syphilis epidemic shall follow .
bummer , AIDS is n't the only STD .
( do n't you just looove acronyms ?
)</tokentext>
<sentencetext>and a syphilis epidemic shall follow.
bummer, AIDS isn't the only STD.
(don't you just looove acronyms?
)</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563599</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563001</id>
	<title>Re:Is this it?</title>
	<author>Anonymous</author>
	<datestamp>1246567440000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext>No.  It'll go the way of HPV.  "This vaccine encourages people to have sex, so we want to forbid children from getting it."  Which will prevent herd immunity even if the religious right's efforts to ban it fail, so HIV will be around forever.</htmltext>
<tokenext>No .
It 'll go the way of HPV .
" This vaccine encourages people to have sex , so we want to forbid children from getting it .
" Which will prevent herd immunity even if the religious right 's efforts to ban it fail , so HIV will be around forever .</tokentext>
<sentencetext>No.
It'll go the way of HPV.
"This vaccine encourages people to have sex, so we want to forbid children from getting it.
"  Which will prevent herd immunity even if the religious right's efforts to ban it fail, so HIV will be around forever.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562707</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562789</id>
	<title>how do you test it?</title>
	<author>Anonymous</author>
	<datestamp>1246566780000</datestamp>
	<modclass>Funny</modclass>
	<modscore>5</modscore>
	<htmltext><p>If I take the vaccine and I only sleep with my wife and in 10 years I'm HIV free does it work?</p><p>Or is one of the pre-requisites of joining the trial that you commit to sleeping with as many sleeezy whores as you can find?</p><p>These are the questions that keep me from being a productive member of society.....</p></htmltext>
<tokenext>If I take the vaccine and I only sleep with my wife and in 10 years I 'm HIV free does it work ? Or is one of the pre-requisites of joining the trial that you commit to sleeping with as many sleeezy whores as you can find ? These are the questions that keep me from being a productive member of society.... .</tokentext>
<sentencetext>If I take the vaccine and I only sleep with my wife and in 10 years I'm HIV free does it work?Or is one of the pre-requisites of joining the trial that you commit to sleeping with as many sleeezy whores as you can find?These are the questions that keep me from being a productive member of society.....</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565011</id>
	<title>Re:Which is It?</title>
	<author>nedlohs</author>
	<datestamp>1246531860000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>Vaccines don't cure things so there's no need to specify that. The unusual case would be a vaccine that did cure an existing condition that would be worthy of mentioning.</p></htmltext>
<tokenext>Vaccines do n't cure things so there 's no need to specify that .
The unusual case would be a vaccine that did cure an existing condition that would be worthy of mentioning .</tokentext>
<sentencetext>Vaccines don't cure things so there's no need to specify that.
The unusual case would be a vaccine that did cure an existing condition that would be worthy of mentioning.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562615</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565511</id>
	<title>Re:No Optimism on HIV</title>
	<author>Anonymous</author>
	<datestamp>1246534500000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><blockquote><div><p>The only way to eradicate this virus is either (1) universal mandatory testing for all Americans and visitors to America</p></div></blockquote><p>How exactly is that going to eradicate HIV from all of the world. It's not like making something mandatory in USNA is going to make it the same in the rest of the world.</p></div>
	</htmltext>
<tokenext>The only way to eradicate this virus is either ( 1 ) universal mandatory testing for all Americans and visitors to AmericaHow exactly is that going to eradicate HIV from all of the world .
It 's not like making something mandatory in USNA is going to make it the same in the rest of the world .</tokentext>
<sentencetext>The only way to eradicate this virus is either (1) universal mandatory testing for all Americans and visitors to AmericaHow exactly is that going to eradicate HIV from all of the world.
It's not like making something mandatory in USNA is going to make it the same in the rest of the world.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562905</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565281</id>
	<title>Re:Is this it?</title>
	<author>Anonymous</author>
	<datestamp>1246533180000</datestamp>
	<modclass>Informativ</modclass>
	<modscore>5</modscore>
	<htmltext><p>A few points;<br>
&nbsp; <br>1: While you can inject the HIV virus into other animals, the virus will not enter their cells due to the variations between human CD40 and the animals' copy. They can get the virus in them, but it won't do anthing. </p><p>2: There are animals whose cell surface ligands are similar enough to the human ones that the virus *does* infect them. if I recall correctly, HIV is capable (though much less efficiently) of entering the cells of certain apes, cats, and armadillos (an eclectic combination to be sure). </p><p>3: Of those animals that will play host to the virus, none of them develop symptoms of AIDS. They will host the virus, spread it around, but will not suffer immunoinhibition. This really isn't that uncommon; humans carry several viruses with no measuarble histological effect. This means that there are no suitable animal models for vaccine testing; human testing really is the only viable option. </p><p>4:It has long been theorized that the difference between being HIV positive and having AIDS is merely the amount of virus spreading in the system. i.e. if you can keep the viral load low enough, you won't get AIDS. If this is indeed the case, then even a therapeutic vaccine will be a huge step forward in the mortality rates of those infected. </p><p>5: Yes, HIV mutates quite quickly. For this reason, the approach that has long been favored is a competitve virus that targets the same cell types as HIV, yet does not have the same level of virulence (a latent infection rather than an actively spreading one). This is the same strategy employed with polio; the original polio vaccine was an actively spreading infectious virus that simply didn't cause the same disease symptoms. It also spread from person to person just like the disease it was meant to treat. This "similar but safer" strategy is likely the only way to have the 'treatment' evolve quickly enough to keep in step with the target. This is also the most difficult type of vaccine for which to acquire testing approval (for obvious reasons).</p><p>6: Other vaccine types are much less likely to be effective against a quickly mutating target like HIV. While they may prime the immune system effectively enough against a single strain of the virus, it's much less likely to work against other strains (same reason that you have to get the flu shot every year rather than just once). </p><p>7: It was recently shown that HIV can spread through cell:cell junctions. This being the case, it is unlikely that typical vaccines (other than live virus) will be effective, because there is no chance for antibodies (the typical immune system mediator) to interfere in this infection process. Now, it is unlikely that cell:cell spread is sufficient to get viral load to the point of causing AIDS, but it is still a factor to be considered when making predictions about vaccine efficacy (viral clearance is extremely unlikely).</p><p>8: This is a phase 1 trial. It's a small scale trial where they're testing for toxicity, not efficacy (phase 2/3). In other words, this trial is designed to answer the question, "is it safe?" It will not answer the question, "does it work?"</p></htmltext>
<tokenext>A few points ;   1 : While you can inject the HIV virus into other animals , the virus will not enter their cells due to the variations between human CD40 and the animals ' copy .
They can get the virus in them , but it wo n't do anthing .
2 : There are animals whose cell surface ligands are similar enough to the human ones that the virus * does * infect them .
if I recall correctly , HIV is capable ( though much less efficiently ) of entering the cells of certain apes , cats , and armadillos ( an eclectic combination to be sure ) .
3 : Of those animals that will play host to the virus , none of them develop symptoms of AIDS .
They will host the virus , spread it around , but will not suffer immunoinhibition .
This really is n't that uncommon ; humans carry several viruses with no measuarble histological effect .
This means that there are no suitable animal models for vaccine testing ; human testing really is the only viable option .
4 : It has long been theorized that the difference between being HIV positive and having AIDS is merely the amount of virus spreading in the system .
i.e. if you can keep the viral load low enough , you wo n't get AIDS .
If this is indeed the case , then even a therapeutic vaccine will be a huge step forward in the mortality rates of those infected .
5 : Yes , HIV mutates quite quickly .
For this reason , the approach that has long been favored is a competitve virus that targets the same cell types as HIV , yet does not have the same level of virulence ( a latent infection rather than an actively spreading one ) .
This is the same strategy employed with polio ; the original polio vaccine was an actively spreading infectious virus that simply did n't cause the same disease symptoms .
It also spread from person to person just like the disease it was meant to treat .
This " similar but safer " strategy is likely the only way to have the 'treatment ' evolve quickly enough to keep in step with the target .
This is also the most difficult type of vaccine for which to acquire testing approval ( for obvious reasons ) .6 : Other vaccine types are much less likely to be effective against a quickly mutating target like HIV .
While they may prime the immune system effectively enough against a single strain of the virus , it 's much less likely to work against other strains ( same reason that you have to get the flu shot every year rather than just once ) .
7 : It was recently shown that HIV can spread through cell : cell junctions .
This being the case , it is unlikely that typical vaccines ( other than live virus ) will be effective , because there is no chance for antibodies ( the typical immune system mediator ) to interfere in this infection process .
Now , it is unlikely that cell : cell spread is sufficient to get viral load to the point of causing AIDS , but it is still a factor to be considered when making predictions about vaccine efficacy ( viral clearance is extremely unlikely ) .8 : This is a phase 1 trial .
It 's a small scale trial where they 're testing for toxicity , not efficacy ( phase 2/3 ) .
In other words , this trial is designed to answer the question , " is it safe ?
" It will not answer the question , " does it work ?
"</tokentext>
<sentencetext>A few points;
  1: While you can inject the HIV virus into other animals, the virus will not enter their cells due to the variations between human CD40 and the animals' copy.
They can get the virus in them, but it won't do anthing.
2: There are animals whose cell surface ligands are similar enough to the human ones that the virus *does* infect them.
if I recall correctly, HIV is capable (though much less efficiently) of entering the cells of certain apes, cats, and armadillos (an eclectic combination to be sure).
3: Of those animals that will play host to the virus, none of them develop symptoms of AIDS.
They will host the virus, spread it around, but will not suffer immunoinhibition.
This really isn't that uncommon; humans carry several viruses with no measuarble histological effect.
This means that there are no suitable animal models for vaccine testing; human testing really is the only viable option.
4:It has long been theorized that the difference between being HIV positive and having AIDS is merely the amount of virus spreading in the system.
i.e. if you can keep the viral load low enough, you won't get AIDS.
If this is indeed the case, then even a therapeutic vaccine will be a huge step forward in the mortality rates of those infected.
5: Yes, HIV mutates quite quickly.
For this reason, the approach that has long been favored is a competitve virus that targets the same cell types as HIV, yet does not have the same level of virulence (a latent infection rather than an actively spreading one).
This is the same strategy employed with polio; the original polio vaccine was an actively spreading infectious virus that simply didn't cause the same disease symptoms.
It also spread from person to person just like the disease it was meant to treat.
This "similar but safer" strategy is likely the only way to have the 'treatment' evolve quickly enough to keep in step with the target.
This is also the most difficult type of vaccine for which to acquire testing approval (for obvious reasons).6: Other vaccine types are much less likely to be effective against a quickly mutating target like HIV.
While they may prime the immune system effectively enough against a single strain of the virus, it's much less likely to work against other strains (same reason that you have to get the flu shot every year rather than just once).
7: It was recently shown that HIV can spread through cell:cell junctions.
This being the case, it is unlikely that typical vaccines (other than live virus) will be effective, because there is no chance for antibodies (the typical immune system mediator) to interfere in this infection process.
Now, it is unlikely that cell:cell spread is sufficient to get viral load to the point of causing AIDS, but it is still a factor to be considered when making predictions about vaccine efficacy (viral clearance is extremely unlikely).8: This is a phase 1 trial.
It's a small scale trial where they're testing for toxicity, not efficacy (phase 2/3).
In other words, this trial is designed to answer the question, "is it safe?
" It will not answer the question, "does it work?
"</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562707</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562615</id>
	<title>Re:Which is It?</title>
	<author>Absolut187</author>
	<datestamp>1246566360000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>2</modscore>
	<htmltext><p>This is a vaccine against getting the HIV virus in the first place.</p><p>There is no "magic serum" that cures AIDS.  If you want to cure your AIDS, you need to have sex with a virgin, preferably an infant.<br><a href="http://www.snopes.com/inboxer/petition/babyrape.asp" title="snopes.com" rel="nofollow">http://www.snopes.com/inboxer/petition/babyrape.asp</a> [snopes.com]</p></htmltext>
<tokenext>This is a vaccine against getting the HIV virus in the first place.There is no " magic serum " that cures AIDS .
If you want to cure your AIDS , you need to have sex with a virgin , preferably an infant.http : //www.snopes.com/inboxer/petition/babyrape.asp [ snopes.com ]</tokentext>
<sentencetext>This is a vaccine against getting the HIV virus in the first place.There is no "magic serum" that cures AIDS.
If you want to cure your AIDS, you need to have sex with a virgin, preferably an infant.http://www.snopes.com/inboxer/petition/babyrape.asp [snopes.com]</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562527</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563191</id>
	<title>Re:Which is It?</title>
	<author>Flea of Pain</author>
	<datestamp>1246568100000</datestamp>
	<modclass>Funny</modclass>
	<modscore>4</modscore>
	<htmltext>Researcher1:  Are you sure this will work?
Researcher2:  Not only am I sure, I'm HIV positive!

Sorry, had to throw a South Park joke in there...</htmltext>
<tokenext>Researcher1 : Are you sure this will work ?
Researcher2 : Not only am I sure , I 'm HIV positive !
Sorry , had to throw a South Park joke in there.. .</tokentext>
<sentencetext>Researcher1:  Are you sure this will work?
Researcher2:  Not only am I sure, I'm HIV positive!
Sorry, had to throw a South Park joke in there...</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562615</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28571205</id>
	<title>Oh George Carlin, You Left Us Too Soon</title>
	<author>CyberPhart</author>
	<datestamp>1246633200000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>I was looking at the objections to the HIV/AIDS vaccine trials from the bible-banger and was immediately put in mind of one of the late, great George Carlin's dialogues.

George was describing being in a social situation and having to listen to drivel from some brain-damaged nitwit. He advised that the socially correct thing to do was to nod politely while making non-committal comments so as not to offend the blathering party. At that point, he began to tremble and, with his eyes bulging, lamented that, from deep within our very souls, wells up the proper but less polite response: "BLOW IT OUT YOUR ASS!", "BLOW IT OUT YOUR ASS!"

Ah George, I do miss you so....</htmltext>
<tokenext>I was looking at the objections to the HIV/AIDS vaccine trials from the bible-banger and was immediately put in mind of one of the late , great George Carlin 's dialogues .
George was describing being in a social situation and having to listen to drivel from some brain-damaged nitwit .
He advised that the socially correct thing to do was to nod politely while making non-committal comments so as not to offend the blathering party .
At that point , he began to tremble and , with his eyes bulging , lamented that , from deep within our very souls , wells up the proper but less polite response : " BLOW IT OUT YOUR ASS !
" , " BLOW IT OUT YOUR ASS !
" Ah George , I do miss you so... .</tokentext>
<sentencetext>I was looking at the objections to the HIV/AIDS vaccine trials from the bible-banger and was immediately put in mind of one of the late, great George Carlin's dialogues.
George was describing being in a social situation and having to listen to drivel from some brain-damaged nitwit.
He advised that the socially correct thing to do was to nod politely while making non-committal comments so as not to offend the blathering party.
At that point, he began to tremble and, with his eyes bulging, lamented that, from deep within our very souls, wells up the proper but less polite response: "BLOW IT OUT YOUR ASS!
", "BLOW IT OUT YOUR ASS!
"

Ah George, I do miss you so....</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562905</id>
	<title>No Optimism on HIV</title>
	<author>Anonymous</author>
	<datestamp>1246567200000</datestamp>
	<modclass>Interestin</modclass>
	<modscore>3</modscore>
	<htmltext>I am not optimistic about this vaccine.  HIV mutates at an astonishing rate, and I doubt that one brand of vaccine can prevent  an infection.
<p>
Right now, we in America -- of all places -- have a silent crisis: an HIV epidemic.  Read the <a href="http://www.washingtonpost.com/wp-dyn/content/article/2009/03/14/AR2009031402176\_pf.html" title="washingtonpost.com" rel="nofollow">shocking article</a> [washingtonpost.com] published recently by "The Washington Post".  About 3\% of the residents of the District of Columbia is infected with HIV.  That percentage is roughly the percentage in Uganda and parts of Kenya.
</p><p>
The only way to eradicate this virus is either (1) universal mandatory testing for all Americans and visitors to America (followed by tough enforcement of laws prohibiting unsafe behavior by those who are infected)  or (2) a gene therapy that transfers the natural immunity enjoyed by a few Europeans to the American population.  As for point #1, mandatory testing is taboo and would never be implemented.  As for point #2, a small percentage of Europeans have a cellular mutation that prevents HIV infection.</p></htmltext>
<tokenext>I am not optimistic about this vaccine .
HIV mutates at an astonishing rate , and I doubt that one brand of vaccine can prevent an infection .
Right now , we in America -- of all places -- have a silent crisis : an HIV epidemic .
Read the shocking article [ washingtonpost.com ] published recently by " The Washington Post " .
About 3 \ % of the residents of the District of Columbia is infected with HIV .
That percentage is roughly the percentage in Uganda and parts of Kenya .
The only way to eradicate this virus is either ( 1 ) universal mandatory testing for all Americans and visitors to America ( followed by tough enforcement of laws prohibiting unsafe behavior by those who are infected ) or ( 2 ) a gene therapy that transfers the natural immunity enjoyed by a few Europeans to the American population .
As for point # 1 , mandatory testing is taboo and would never be implemented .
As for point # 2 , a small percentage of Europeans have a cellular mutation that prevents HIV infection .</tokentext>
<sentencetext>I am not optimistic about this vaccine.
HIV mutates at an astonishing rate, and I doubt that one brand of vaccine can prevent  an infection.
Right now, we in America -- of all places -- have a silent crisis: an HIV epidemic.
Read the shocking article [washingtonpost.com] published recently by "The Washington Post".
About 3\% of the residents of the District of Columbia is infected with HIV.
That percentage is roughly the percentage in Uganda and parts of Kenya.
The only way to eradicate this virus is either (1) universal mandatory testing for all Americans and visitors to America (followed by tough enforcement of laws prohibiting unsafe behavior by those who are infected)  or (2) a gene therapy that transfers the natural immunity enjoyed by a few Europeans to the American population.
As for point #1, mandatory testing is taboo and would never be implemented.
As for point #2, a small percentage of Europeans have a cellular mutation that prevents HIV infection.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563599</id>
	<title>Hicks</title>
	<author>WilyCoder</author>
	<datestamp>1246526160000</datestamp>
	<modclass>Funny</modclass>
	<modscore>3</modscore>
	<htmltext><p>When they find a cure for HIV there will be fucking in the streets.</p><p>-Bill Hicks</p></htmltext>
<tokenext>When they find a cure for HIV there will be fucking in the streets.-Bill Hicks</tokentext>
<sentencetext>When they find a cure for HIV there will be fucking in the streets.-Bill Hicks</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565787</id>
	<title>Yay</title>
	<author>mqduck</author>
	<datestamp>1246536000000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>Great! Now we can start fucking again (so long as birth control is used) without any concern about anything bad happening ever again, right?</p><p>RIGHT??</p></htmltext>
<tokenext>Great !
Now we can start fucking again ( so long as birth control is used ) without any concern about anything bad happening ever again , right ? RIGHT ?
?</tokentext>
<sentencetext>Great!
Now we can start fucking again (so long as birth control is used) without any concern about anything bad happening ever again, right?RIGHT?
?</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28566657</id>
	<title>Re:Which is It?</title>
	<author>Baseclass</author>
	<datestamp>1246541040000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>Not a cure for aids but vaccine as the article stated.</htmltext>
<tokenext>Not a cure for aids but vaccine as the article stated .</tokentext>
<sentencetext>Not a cure for aids but vaccine as the article stated.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562527</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563453</id>
	<title>Re:Which is It?</title>
	<author>Anonymous</author>
	<datestamp>1246525740000</datestamp>
	<modclass>Informativ</modclass>
	<modscore>2</modscore>
	<htmltext><p>I would use my mod points to help you, but I think it's best to post a reply telling future moderators that the above is not a troll. That is what I thought before clicking the link. This is in fact a post spreading the awareness of child abuse in South Africa (at times resulting in gang-rape of an infant) because of the foolish and terrible myth that having sex with a virgin infant can cure your AIDS. Click on the link and help with the petition if you are interested</p></htmltext>
<tokenext>I would use my mod points to help you , but I think it 's best to post a reply telling future moderators that the above is not a troll .
That is what I thought before clicking the link .
This is in fact a post spreading the awareness of child abuse in South Africa ( at times resulting in gang-rape of an infant ) because of the foolish and terrible myth that having sex with a virgin infant can cure your AIDS .
Click on the link and help with the petition if you are interested</tokentext>
<sentencetext>I would use my mod points to help you, but I think it's best to post a reply telling future moderators that the above is not a troll.
That is what I thought before clicking the link.
This is in fact a post spreading the awareness of child abuse in South Africa (at times resulting in gang-rape of an infant) because of the foolish and terrible myth that having sex with a virgin infant can cure your AIDS.
Click on the link and help with the petition if you are interested</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562615</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28566755</id>
	<title>Re:Is this it?</title>
	<author>unifyingtheory</author>
	<datestamp>1246541760000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><i>Sounds like if this is for real, HIV will go the way of smallpox and polio.</i> <br> <br>
Funny you should mention polio because Africa is the last continent that still has polio infection.  Africa is also the heart of the AIDS epidemic.</htmltext>
<tokenext>Sounds like if this is for real , HIV will go the way of smallpox and polio .
Funny you should mention polio because Africa is the last continent that still has polio infection .
Africa is also the heart of the AIDS epidemic .</tokentext>
<sentencetext>Sounds like if this is for real, HIV will go the way of smallpox and polio.
Funny you should mention polio because Africa is the last continent that still has polio infection.
Africa is also the heart of the AIDS epidemic.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562707</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28566923</id>
	<title>HIV/AIDS Vaccine vs Marrow Cure via CCR5 Mutation</title>
	<author>RandomUsr</author>
	<datestamp>1246543200000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>I wonder how many people will think it's ok to have unprotected sex because they've either had the Vaccine or they figure they can have a Marrow Transplant from a donor that has the CCR5 receptor mutation.

The CCR5 mutation is soo rare however that very few people could even consider it. One has to wonder if this can be introduced via artificial insemination thus creating a baby who might have natural resistance to HIV.

The Vaccine would only be interesting to those doing Drugs, those sleeping around, and those afraid of their partners doing the first two. I jest, however as this is not only important to these groups, but you'd think adults could handle sexual responsibility,  wait....

So my question then becomes, Do parents rely on gene therapy whic could have fewer side effects or just say F--- it, let the
Wedlock child take the cheap vaccine.

This is the cultural reality, is it not?</htmltext>
<tokenext>I wonder how many people will think it 's ok to have unprotected sex because they 've either had the Vaccine or they figure they can have a Marrow Transplant from a donor that has the CCR5 receptor mutation .
The CCR5 mutation is soo rare however that very few people could even consider it .
One has to wonder if this can be introduced via artificial insemination thus creating a baby who might have natural resistance to HIV .
The Vaccine would only be interesting to those doing Drugs , those sleeping around , and those afraid of their partners doing the first two .
I jest , however as this is not only important to these groups , but you 'd think adults could handle sexual responsibility , wait... . So my question then becomes , Do parents rely on gene therapy whic could have fewer side effects or just say F--- it , let the Wedlock child take the cheap vaccine .
This is the cultural reality , is it not ?</tokentext>
<sentencetext>I wonder how many people will think it's ok to have unprotected sex because they've either had the Vaccine or they figure they can have a Marrow Transplant from a donor that has the CCR5 receptor mutation.
The CCR5 mutation is soo rare however that very few people could even consider it.
One has to wonder if this can be introduced via artificial insemination thus creating a baby who might have natural resistance to HIV.
The Vaccine would only be interesting to those doing Drugs, those sleeping around, and those afraid of their partners doing the first two.
I jest, however as this is not only important to these groups, but you'd think adults could handle sexual responsibility,  wait....

So my question then becomes, Do parents rely on gene therapy whic could have fewer side effects or just say F--- it, let the
Wedlock child take the cheap vaccine.
This is the cultural reality, is it not?</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28567109</id>
	<title>Re:Which is It?</title>
	<author>s4ltyd0g</author>
	<datestamp>1246544580000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>One would hope that a person with AIDS would realize that unprotected sex willy-nilly can never be an option for them vaccine or not.</p></htmltext>
<tokenext>One would hope that a person with AIDS would realize that unprotected sex willy-nilly can never be an option for them vaccine or not .</tokentext>
<sentencetext>One would hope that a person with AIDS would realize that unprotected sex willy-nilly can never be an option for them vaccine or not.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562527</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28566769</id>
	<title>Re:No Optimism on HIV</title>
	<author>Anonymous</author>
	<datestamp>1246541940000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>I am not optimistic about this vaccine<br>Nor am I, but I only wish herpes would get as much attention. The two usually go hand in hand, not only does having HPV greatly increase the chances for HIV transmission, it also decreases the chances of HIV survival.</p><p>For the uninformed:<br>There's 2 types, HSV-1 and HSV-2.  HSV1 usually causes what is known as "fever-blisters" or "cold-sores" (although having "fever-blisters" or "cold-sores" does not necessarily mean you have herpes) and HSV-2 typically causes what is known as genital herpes.  What is usually ignored is that both types are very similar (having close to 50\% of the same DNA), both can spread to other parts of the body (although this is usually limited to HPV-1), and both typically remain with the infected for life with no know cure, only treatment for the symptoms.</p><p>If the outbreaks aren't bad enough, the virus has other complications as well. Both forms have also been linked to nerve damage, blindness (via the infection spreading to the eyes), increased chances for other infection (via weakening the immune system and through breaks in the skin) and even death through encephalitis.  There's also have been studies that show possible links to arthritis, Bell's palsy, alzheimer's, and pneumonia.  How bad the infection is mainly depends on the health of the individual and their immune system, many may not even know they're infected.</p><p>The really scary part is the statistics, a 3\% HIV infection may gain notoriety due to it's likelihood to kill those infected without special treatment, but HPV (herpes) is far beyond epidemic proportions and it still hasn't seemed to attract much public attention:</p><p>It's estimated that HSV-2 has infected ~20\% of the US and although HSC-2 can be spread just skin contact, it is usually requires sexual contact.</p><p>HSV-1, on the other hand, is estimated to have infected roughly <b>60\% of the US population</b>, and can be spread both by direct and indirect skin contact.  There are countless vectors, you can transmit it with; sharing a drink, a handshake, clothes, a toothbrush, a kiss, you name it.</p></htmltext>
<tokenext>I am not optimistic about this vaccineNor am I , but I only wish herpes would get as much attention .
The two usually go hand in hand , not only does having HPV greatly increase the chances for HIV transmission , it also decreases the chances of HIV survival.For the uninformed : There 's 2 types , HSV-1 and HSV-2 .
HSV1 usually causes what is known as " fever-blisters " or " cold-sores " ( although having " fever-blisters " or " cold-sores " does not necessarily mean you have herpes ) and HSV-2 typically causes what is known as genital herpes .
What is usually ignored is that both types are very similar ( having close to 50 \ % of the same DNA ) , both can spread to other parts of the body ( although this is usually limited to HPV-1 ) , and both typically remain with the infected for life with no know cure , only treatment for the symptoms.If the outbreaks are n't bad enough , the virus has other complications as well .
Both forms have also been linked to nerve damage , blindness ( via the infection spreading to the eyes ) , increased chances for other infection ( via weakening the immune system and through breaks in the skin ) and even death through encephalitis .
There 's also have been studies that show possible links to arthritis , Bell 's palsy , alzheimer 's , and pneumonia .
How bad the infection is mainly depends on the health of the individual and their immune system , many may not even know they 're infected.The really scary part is the statistics , a 3 \ % HIV infection may gain notoriety due to it 's likelihood to kill those infected without special treatment , but HPV ( herpes ) is far beyond epidemic proportions and it still has n't seemed to attract much public attention : It 's estimated that HSV-2 has infected ~ 20 \ % of the US and although HSC-2 can be spread just skin contact , it is usually requires sexual contact.HSV-1 , on the other hand , is estimated to have infected roughly 60 \ % of the US population , and can be spread both by direct and indirect skin contact .
There are countless vectors , you can transmit it with ; sharing a drink , a handshake , clothes , a toothbrush , a kiss , you name it .</tokentext>
<sentencetext>I am not optimistic about this vaccineNor am I, but I only wish herpes would get as much attention.
The two usually go hand in hand, not only does having HPV greatly increase the chances for HIV transmission, it also decreases the chances of HIV survival.For the uninformed:There's 2 types, HSV-1 and HSV-2.
HSV1 usually causes what is known as "fever-blisters" or "cold-sores" (although having "fever-blisters" or "cold-sores" does not necessarily mean you have herpes) and HSV-2 typically causes what is known as genital herpes.
What is usually ignored is that both types are very similar (having close to 50\% of the same DNA), both can spread to other parts of the body (although this is usually limited to HPV-1), and both typically remain with the infected for life with no know cure, only treatment for the symptoms.If the outbreaks aren't bad enough, the virus has other complications as well.
Both forms have also been linked to nerve damage, blindness (via the infection spreading to the eyes), increased chances for other infection (via weakening the immune system and through breaks in the skin) and even death through encephalitis.
There's also have been studies that show possible links to arthritis, Bell's palsy, alzheimer's, and pneumonia.
How bad the infection is mainly depends on the health of the individual and their immune system, many may not even know they're infected.The really scary part is the statistics, a 3\% HIV infection may gain notoriety due to it's likelihood to kill those infected without special treatment, but HPV (herpes) is far beyond epidemic proportions and it still hasn't seemed to attract much public attention:It's estimated that HSV-2 has infected ~20\% of the US and although HSC-2 can be spread just skin contact, it is usually requires sexual contact.HSV-1, on the other hand, is estimated to have infected roughly 60\% of the US population, and can be spread both by direct and indirect skin contact.
There are countless vectors, you can transmit it with; sharing a drink, a handshake, clothes, a toothbrush, a kiss, you name it.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562905</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563847</id>
	<title>Re:Which is It?</title>
	<author>Anonymous</author>
	<datestamp>1246527180000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>Does it also bother you when people use their and there interchangeably? Or it's and its? Because the rest of us all get what they mean by an "HIV/AIDS Vaccine", and it seems you do too... you're just being needlessly pedantic.</p></htmltext>
<tokenext>Does it also bother you when people use their and there interchangeably ?
Or it 's and its ?
Because the rest of us all get what they mean by an " HIV/AIDS Vaccine " , and it seems you do too... you 're just being needlessly pedantic .</tokentext>
<sentencetext>Does it also bother you when people use their and there interchangeably?
Or it's and its?
Because the rest of us all get what they mean by an "HIV/AIDS Vaccine", and it seems you do too... you're just being needlessly pedantic.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563149</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562625</id>
	<title>RTFA</title>
	<author>Swordopolis</author>
	<datestamp>1246566360000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>"We hope this vaccine is it, and hopefully this vaccine will prevent HIV infection and save millions of lives."</p></htmltext>
<tokenext>" We hope this vaccine is it , and hopefully this vaccine will prevent HIV infection and save millions of lives .
"</tokentext>
<sentencetext>"We hope this vaccine is it, and hopefully this vaccine will prevent HIV infection and save millions of lives.
"</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562527</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562707</id>
	<title>Is this it?</title>
	<author>davek</author>
	<datestamp>1246566600000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>4</modscore>
	<htmltext><p>From TFA:</p><p><div class="quote"><p>"We hope this vaccine is it, and hopefully this vaccine will prevent HIV infection and save millions of lives." University of Western Ontario professor Chil-Yong Kang.</p></div><p><div class="quote"><p>Human trials are necessary to test the efficacy of the vaccine in protecting against HIV infection because the HIV virus does not cause AIDS-like symptoms in animals, says Kang. However, the immune responses in the animal trials have been promising, he says.</p></div><p>Sounds like if this is for real, HIV will go the way of smallpox and polio.  Is this as huge as it sounds?</p></div>
	</htmltext>
<tokenext>From TFA : " We hope this vaccine is it , and hopefully this vaccine will prevent HIV infection and save millions of lives .
" University of Western Ontario professor Chil-Yong Kang.Human trials are necessary to test the efficacy of the vaccine in protecting against HIV infection because the HIV virus does not cause AIDS-like symptoms in animals , says Kang .
However , the immune responses in the animal trials have been promising , he says.Sounds like if this is for real , HIV will go the way of smallpox and polio .
Is this as huge as it sounds ?</tokentext>
<sentencetext>From TFA:"We hope this vaccine is it, and hopefully this vaccine will prevent HIV infection and save millions of lives.
" University of Western Ontario professor Chil-Yong Kang.Human trials are necessary to test the efficacy of the vaccine in protecting against HIV infection because the HIV virus does not cause AIDS-like symptoms in animals, says Kang.
However, the immune responses in the animal trials have been promising, he says.Sounds like if this is for real, HIV will go the way of smallpox and polio.
Is this as huge as it sounds?
	</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565507</id>
	<title>Re:Is this it?</title>
	<author>h3llfish</author>
	<datestamp>1246534500000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>No, this is nothing to get excited about.  It's not even newsworthy.  Dozens of other potential vaccines have made a splash in the media, but ultimately proved ineffective.  I really do hope that this is the one, but... call me when it WORKS.</htmltext>
<tokenext>No , this is nothing to get excited about .
It 's not even newsworthy .
Dozens of other potential vaccines have made a splash in the media , but ultimately proved ineffective .
I really do hope that this is the one , but... call me when it WORKS .</tokentext>
<sentencetext>No, this is nothing to get excited about.
It's not even newsworthy.
Dozens of other potential vaccines have made a splash in the media, but ultimately proved ineffective.
I really do hope that this is the one, but... call me when it WORKS.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562707</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563069</id>
	<title>Re:No Optimism on HIV</title>
	<author>Anonymous</author>
	<datestamp>1246567680000</datestamp>
	<modclass>Troll</modclass>
	<modscore>0</modscore>
	<htmltext><p>Or, just let the disease kill all the morons, and quit strapping the rest of society with the financial burden of keeping these twits 1.) Alive, 2.) Believing that they're entitled to existence despite the fact that they've engaged in behavior that is obviously counter self-preservation in our current society.</p><p>DUH.</p><p>You do not have a right to burden society through your existence.</p><p>This is not a question of race, sexuality, or ethnicity. It's a case of stupid people doing stupid things, getting a chronic and fatal disease. Let them die. They're stupid, and they place the rest of us (especially the bleeding hearts who want to help really really badly) at risk.</p><p>I say, bring back the leper colonies -- except make them HIV / AIDS colonies.</p></htmltext>
<tokenext>Or , just let the disease kill all the morons , and quit strapping the rest of society with the financial burden of keeping these twits 1 .
) Alive , 2 .
) Believing that they 're entitled to existence despite the fact that they 've engaged in behavior that is obviously counter self-preservation in our current society.DUH.You do not have a right to burden society through your existence.This is not a question of race , sexuality , or ethnicity .
It 's a case of stupid people doing stupid things , getting a chronic and fatal disease .
Let them die .
They 're stupid , and they place the rest of us ( especially the bleeding hearts who want to help really really badly ) at risk.I say , bring back the leper colonies -- except make them HIV / AIDS colonies .</tokentext>
<sentencetext>Or, just let the disease kill all the morons, and quit strapping the rest of society with the financial burden of keeping these twits 1.
) Alive, 2.
) Believing that they're entitled to existence despite the fact that they've engaged in behavior that is obviously counter self-preservation in our current society.DUH.You do not have a right to burden society through your existence.This is not a question of race, sexuality, or ethnicity.
It's a case of stupid people doing stupid things, getting a chronic and fatal disease.
Let them die.
They're stupid, and they place the rest of us (especially the bleeding hearts who want to help really really badly) at risk.I say, bring back the leper colonies -- except make them HIV / AIDS colonies.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562905</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564325</id>
	<title>Re:Test on</title>
	<author>Anonymous</author>
	<datestamp>1246528980000</datestamp>
	<modclass>Interestin</modclass>
	<modscore>3</modscore>
	<htmltext>Actually drugs trials did take place on African people with AIDS without their knowledge. The would inject them with supposedly malaria drugs, along with other drugs. And test them a few months later...</htmltext>
<tokenext>Actually drugs trials did take place on African people with AIDS without their knowledge .
The would inject them with supposedly malaria drugs , along with other drugs .
And test them a few months later.. .</tokentext>
<sentencetext>Actually drugs trials did take place on African people with AIDS without their knowledge.
The would inject them with supposedly malaria drugs, along with other drugs.
And test them a few months later...</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562583</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563145</id>
	<title>Re:Which is It?</title>
	<author>Ian Alexander</author>
	<datestamp>1246567920000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>2</modscore>
	<htmltext>If you have AIDS you're probably better-educated about your syndrome than your average bear.<br> <br>I find it highly improbably that anyone could confuse AIDS and HIV that badly; I was educated on the difference in middle school as part and parcel of the health curriculum.</htmltext>
<tokenext>If you have AIDS you 're probably better-educated about your syndrome than your average bear .
I find it highly improbably that anyone could confuse AIDS and HIV that badly ; I was educated on the difference in middle school as part and parcel of the health curriculum .</tokentext>
<sentencetext>If you have AIDS you're probably better-educated about your syndrome than your average bear.
I find it highly improbably that anyone could confuse AIDS and HIV that badly; I was educated on the difference in middle school as part and parcel of the health curriculum.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562527</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28569913</id>
	<title>Re:Which is It?</title>
	<author>jacquesm</author>
	<datestamp>1246620540000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>having unprotected sex willy-nilly with or without aids is dangerous anyway and should be avoided.</p><p>There are more STDs out there than you can count on the fingers of your two hands and toes and<br>some of them have very serious effects.</p></htmltext>
<tokenext>having unprotected sex willy-nilly with or without aids is dangerous anyway and should be avoided.There are more STDs out there than you can count on the fingers of your two hands and toes andsome of them have very serious effects .</tokentext>
<sentencetext>having unprotected sex willy-nilly with or without aids is dangerous anyway and should be avoided.There are more STDs out there than you can count on the fingers of your two hands and toes andsome of them have very serious effects.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562527</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562981</id>
	<title>Re:Is this it?</title>
	<author>Anonymous</author>
	<datestamp>1246567380000</datestamp>
	<modclass>Informativ</modclass>
	<modscore>4</modscore>
	<htmltext>The question is really if this is a vaccine or therapeutic vaccine, I couldn't find that in the article. The difference being a regular vaccine will prevent the virus from infecting you while a therapeutic will either prevent the virus from spreading in your body but you might still be a carrier or eradicate the virus from you completely thus destroying it.
<br>
<br>
<br>
Just a side note since a lot of discussion on HIV and AIDS. HIV is the virus, the virus attacks the immune system destroying your white blood cells, when your white blood cell count falls below a certain amount per 1mm of blood or some measurement you have AIDS or auto-immune deficiency syndrome caused by HIV.
<br>
<br>
<br>
The virus wont kill you, what will kill you in the end is a basic infection that your body cant handle, even the common cold.</htmltext>
<tokenext>The question is really if this is a vaccine or therapeutic vaccine , I could n't find that in the article .
The difference being a regular vaccine will prevent the virus from infecting you while a therapeutic will either prevent the virus from spreading in your body but you might still be a carrier or eradicate the virus from you completely thus destroying it .
Just a side note since a lot of discussion on HIV and AIDS .
HIV is the virus , the virus attacks the immune system destroying your white blood cells , when your white blood cell count falls below a certain amount per 1mm of blood or some measurement you have AIDS or auto-immune deficiency syndrome caused by HIV .
The virus wont kill you , what will kill you in the end is a basic infection that your body cant handle , even the common cold .</tokentext>
<sentencetext>The question is really if this is a vaccine or therapeutic vaccine, I couldn't find that in the article.
The difference being a regular vaccine will prevent the virus from infecting you while a therapeutic will either prevent the virus from spreading in your body but you might still be a carrier or eradicate the virus from you completely thus destroying it.
Just a side note since a lot of discussion on HIV and AIDS.
HIV is the virus, the virus attacks the immune system destroying your white blood cells, when your white blood cell count falls below a certain amount per 1mm of blood or some measurement you have AIDS or auto-immune deficiency syndrome caused by HIV.
The virus wont kill you, what will kill you in the end is a basic infection that your body cant handle, even the common cold.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562707</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565429</id>
	<title>Re:how do you test it?</title>
	<author>Anonymous</author>
	<datestamp>1246534020000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>Hopefully they will keep you from being a reproductive member of society, too.</p></htmltext>
<tokenext>Hopefully they will keep you from being a reproductive member of society , too .</tokentext>
<sentencetext>Hopefully they will keep you from being a reproductive member of society, too.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562789</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565247</id>
	<title>Re:Hicks</title>
	<author>TheRaven64</author>
	<datestamp>1246532940000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>2</modscore>
	<htmltext>Right until people realise that there still isn't a cure or vaccine for herpes...</htmltext>
<tokenext>Right until people realise that there still is n't a cure or vaccine for herpes.. .</tokentext>
<sentencetext>Right until people realise that there still isn't a cure or vaccine for herpes...</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563599</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28567127</id>
	<title>Re:Is this it?</title>
	<author>Anonymous</author>
	<datestamp>1246544700000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>I don't know. The dormancy period of AIDS is so much that I think if it fell of the public's radar, people would stop practicing safe sex, and after 10,15, or 20 years, we would have a resurgence of AIDS cases. I think that's sort of happening now, if I understand correctly.</htmltext>
<tokenext>I do n't know .
The dormancy period of AIDS is so much that I think if it fell of the public 's radar , people would stop practicing safe sex , and after 10,15 , or 20 years , we would have a resurgence of AIDS cases .
I think that 's sort of happening now , if I understand correctly .</tokentext>
<sentencetext>I don't know.
The dormancy period of AIDS is so much that I think if it fell of the public's radar, people would stop practicing safe sex, and after 10,15, or 20 years, we would have a resurgence of AIDS cases.
I think that's sort of happening now, if I understand correctly.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564107</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28566641</id>
	<title>Re:No Optimism on HIV</title>
	<author>CodeBuster</author>
	<datestamp>1246540980000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><div class="quote"><p>HIV mutates at an astonishing rate</p></div><p>In fact there is a different type of treatment that takes advantage of that very fact, accelerating the rate of mutation so much that the virus is unable to remain viable. This approach to anti-retroviral therapy is called <a href="http://en.wikipedia.org/wiki/Error\_catastrophe" title="wikipedia.org">error catastrophe</a> [wikipedia.org] and a promising enzyme, KP-1461, is currently being investigated for its ability to cause this chain reaction with HIV.</p></div>
	</htmltext>
<tokenext>HIV mutates at an astonishing rateIn fact there is a different type of treatment that takes advantage of that very fact , accelerating the rate of mutation so much that the virus is unable to remain viable .
This approach to anti-retroviral therapy is called error catastrophe [ wikipedia.org ] and a promising enzyme , KP-1461 , is currently being investigated for its ability to cause this chain reaction with HIV .</tokentext>
<sentencetext>HIV mutates at an astonishing rateIn fact there is a different type of treatment that takes advantage of that very fact, accelerating the rate of mutation so much that the virus is unable to remain viable.
This approach to anti-retroviral therapy is called error catastrophe [wikipedia.org] and a promising enzyme, KP-1461, is currently being investigated for its ability to cause this chain reaction with HIV.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562905</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564263</id>
	<title>Re:Cue objections from the religious right:</title>
	<author>Anonymous</author>
	<datestamp>1246528740000</datestamp>
	<modclass>Interestin</modclass>
	<modscore>2</modscore>
	<htmltext>The Christian religion clearly states that the world and humans were Created and did not evolve before then, they may have evolved afterward, but not prior.

Can you please clarify your position as a Christian who believes in Evolution?</htmltext>
<tokenext>The Christian religion clearly states that the world and humans were Created and did not evolve before then , they may have evolved afterward , but not prior .
Can you please clarify your position as a Christian who believes in Evolution ?</tokentext>
<sentencetext>The Christian religion clearly states that the world and humans were Created and did not evolve before then, they may have evolved afterward, but not prior.
Can you please clarify your position as a Christian who believes in Evolution?</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562683</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563705</id>
	<title>Re:how do you test it?</title>
	<author>Anonymous</author>
	<datestamp>1246526520000</datestamp>
	<modclass>Redundant</modclass>
	<modscore>-1</modscore>
	<htmltext><p><div class="quote"><p>These are the questions that keep me from being a <b>reproductive</b> member of society....</p></div><p>It's okay, we all Freudian slip sometimes.</p></div>
	</htmltext>
<tokenext>These are the questions that keep me from being a reproductive member of society....It 's okay , we all Freudian slip sometimes .</tokentext>
<sentencetext>These are the questions that keep me from being a reproductive member of society....It's okay, we all Freudian slip sometimes.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562789</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563773</id>
	<title>Test: How?</title>
	<author>Anonymous</author>
	<datestamp>1246526820000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>I mean, how are they going to really test that it works? Because, I am sure there are just tons of people out there that want to be exposed to HIV just to see if the vaccine they took actually keeps you from getting a virus that WILL kill you.</htmltext>
<tokenext>I mean , how are they going to really test that it works ?
Because , I am sure there are just tons of people out there that want to be exposed to HIV just to see if the vaccine they took actually keeps you from getting a virus that WILL kill you .</tokentext>
<sentencetext>I mean, how are they going to really test that it works?
Because, I am sure there are just tons of people out there that want to be exposed to HIV just to see if the vaccine they took actually keeps you from getting a virus that WILL kill you.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28572939</id>
	<title>Re:No Optimism on HIV</title>
	<author>Anonymous</author>
	<datestamp>1246643520000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p><div class="quote"><p>The only way to eradicate this virus is either (1) universal mandatory testing for all Americans and visitors to America (followed by tough enforcement of laws prohibiting unsafe behavior by those who are infected) or (2) a gene therapy</p></div><p>How about actually treating it where it's rampant, and how about (killing the pope and) teaching people about safer sex? HIV would never have gotten so big if there were a functioning general health system in African countries and in the US. Most European countries have better health systems than the US. Using border control, especially against a virus that is already so widespread in your country, is just silly, and gene therapy... maybe in 100 years.</p></div>
	</htmltext>
<tokenext>The only way to eradicate this virus is either ( 1 ) universal mandatory testing for all Americans and visitors to America ( followed by tough enforcement of laws prohibiting unsafe behavior by those who are infected ) or ( 2 ) a gene therapyHow about actually treating it where it 's rampant , and how about ( killing the pope and ) teaching people about safer sex ?
HIV would never have gotten so big if there were a functioning general health system in African countries and in the US .
Most European countries have better health systems than the US .
Using border control , especially against a virus that is already so widespread in your country , is just silly , and gene therapy... maybe in 100 years .</tokentext>
<sentencetext>The only way to eradicate this virus is either (1) universal mandatory testing for all Americans and visitors to America (followed by tough enforcement of laws prohibiting unsafe behavior by those who are infected) or (2) a gene therapyHow about actually treating it where it's rampant, and how about (killing the pope and) teaching people about safer sex?
HIV would never have gotten so big if there were a functioning general health system in African countries and in the US.
Most European countries have better health systems than the US.
Using border control, especially against a virus that is already so widespread in your country, is just silly, and gene therapy... maybe in 100 years.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562905</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562683</id>
	<title>Re:Cue objections from the religious right:</title>
	<author>Anonymous</author>
	<datestamp>1246566540000</datestamp>
	<modclass>Interestin</modclass>
	<modscore>4</modscore>
	<htmltext>Not all of us conservative Christians are superstitious like you illustrate. Some of us even believe in evolution. Some of us don't mind gays getting married. People want to believe that the stereotype is real though, and you don't help the situation.</htmltext>
<tokenext>Not all of us conservative Christians are superstitious like you illustrate .
Some of us even believe in evolution .
Some of us do n't mind gays getting married .
People want to believe that the stereotype is real though , and you do n't help the situation .</tokentext>
<sentencetext>Not all of us conservative Christians are superstitious like you illustrate.
Some of us even believe in evolution.
Some of us don't mind gays getting married.
People want to believe that the stereotype is real though, and you don't help the situation.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562581</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564193</id>
	<title>Re:RTFA</title>
	<author>Anonymous</author>
	<datestamp>1246528500000</datestamp>
	<modclass>Troll</modclass>
	<modscore>-1</modscore>
	<htmltext><p>Then people can buttfuck each other with impunity.</p></htmltext>
<tokenext>Then people can buttfuck each other with impunity .</tokentext>
<sentencetext>Then people can buttfuck each other with impunity.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562625</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28569567</id>
	<title>Re:Is this it?</title>
	<author>Hurricane78</author>
	<datestamp>1246615920000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>But how can you get rich from that?</p><p>-- Your pharma industry.</p></htmltext>
<tokenext>But how can you get rich from that ? -- Your pharma industry .</tokentext>
<sentencetext>But how can you get rich from that?-- Your pharma industry.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564107</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28569445</id>
	<title>Re:Which is It?</title>
	<author>Hurricane78</author>
	<datestamp>1246614780000</datestamp>
	<modclass>Interestin</modclass>
	<modscore>1</modscore>
	<htmltext><p><div class="quote"><p>There is no "magic serum" that cures AIDS.</p></div><p>Typical medical doctor behavior. In reality, you should say:</p><p><div class="quote"><p> <strong>I</strong> do not <strong>KNOW</strong> of a serum that cures AIDS <strong>YET</strong>.</p></div><p>You know, you aren't god, despite you possibly thinking so. ^^<br>You can not predict that it will never happen. You can not say if it's just you being uninformed.<br>You can not know if humanity as a whole just does not know enough yet.<br>And most likely, you are wrong with all three assumptions.</p></div>
	</htmltext>
<tokenext>There is no " magic serum " that cures AIDS.Typical medical doctor behavior .
In reality , you should say : I do not KNOW of a serum that cures AIDS YET.You know , you are n't god , despite you possibly thinking so .
^ ^ You can not predict that it will never happen .
You can not say if it 's just you being uninformed.You can not know if humanity as a whole just does not know enough yet.And most likely , you are wrong with all three assumptions .</tokentext>
<sentencetext>There is no "magic serum" that cures AIDS.Typical medical doctor behavior.
In reality, you should say: I do not KNOW of a serum that cures AIDS YET.You know, you aren't god, despite you possibly thinking so.
^^You can not predict that it will never happen.
You can not say if it's just you being uninformed.You can not know if humanity as a whole just does not know enough yet.And most likely, you are wrong with all three assumptions.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562615</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565751</id>
	<title>Re:Cue objections from the religious right:</title>
	<author>grolschie</author>
	<datestamp>1246535820000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><div class="quote"><p>Can you please clarify your position as a Christian who believes in Evolution?</p></div><p>One can believe in evolution (e.g. <a href="http://en.wikipedia.org/wiki/Microevolution" title="wikipedia.org">Microevolution</a> [wikipedia.org], which is observable) while not believing in <a href="http://en.wikipedia.org/wiki/Common\_descent" title="wikipedia.org">Common Descent</a> [wikipedia.org]. This doesn't not contradict the belief that man was literally created in the God's image.</p></div>
	</htmltext>
<tokenext>Can you please clarify your position as a Christian who believes in Evolution ? One can believe in evolution ( e.g .
Microevolution [ wikipedia.org ] , which is observable ) while not believing in Common Descent [ wikipedia.org ] .
This does n't not contradict the belief that man was literally created in the God 's image .</tokentext>
<sentencetext>Can you please clarify your position as a Christian who believes in Evolution?One can believe in evolution (e.g.
Microevolution [wikipedia.org], which is observable) while not believing in Common Descent [wikipedia.org].
This doesn't not contradict the belief that man was literally created in the God's image.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564263</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28574627</id>
	<title>oblig</title>
	<author>Anonymous</author>
	<datestamp>1246612200000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>Phase 1 - human trials<br>Phase 2 - ?????<br>Phase 3 - Profits</p></htmltext>
<tokenext>Phase 1 - human trialsPhase 2 - ? ? ? ?
? Phase 3 - Profits</tokentext>
<sentencetext>Phase 1 - human trialsPhase 2 - ????
?Phase 3 - Profits</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564257</id>
	<title>Fixed that for you ;)</title>
	<author>turing\_m</author>
	<datestamp>1246528680000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><blockquote><div><p>(3) Abstaining/reducing risky sexual behaviors <b>involving other people</b>. For slashdotters, this shouldn't be a problem.</p></div></blockquote></div>
	</htmltext>
<tokenext>( 3 ) Abstaining/reducing risky sexual behaviors involving other people .
For slashdotters , this should n't be a problem .</tokentext>
<sentencetext>(3) Abstaining/reducing risky sexual behaviors involving other people.
For slashdotters, this shouldn't be a problem.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563201</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562831</id>
	<title>Yay!</title>
	<author>brian0918</author>
	<datestamp>1246566960000</datestamp>
	<modclass>Troll</modclass>
	<modscore>0</modscore>
	<htmltext>Just 80,000 more government hoops to jump through, and we could one day be allowed to save the lives of our loved ones who in the mean time have died. Thank you, federal government, for saving us from making decisions for ourselves!</htmltext>
<tokenext>Just 80,000 more government hoops to jump through , and we could one day be allowed to save the lives of our loved ones who in the mean time have died .
Thank you , federal government , for saving us from making decisions for ourselves !</tokentext>
<sentencetext>Just 80,000 more government hoops to jump through, and we could one day be allowed to save the lives of our loved ones who in the mean time have died.
Thank you, federal government, for saving us from making decisions for ourselves!</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28568339</id>
	<title>University of Western Ontario</title>
	<author>Anonymous</author>
	<datestamp>1246555740000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>Socialized health care and government funded research to the rescue!</p></htmltext>
<tokenext>Socialized health care and government funded research to the rescue !</tokentext>
<sentencetext>Socialized health care and government funded research to the rescue!</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562771</id>
	<title>Re:Which is It?</title>
	<author>greatica</author>
	<datestamp>1246566780000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext>Nah, you cure it by taking walks along the beach, climbing rocks, and mountain biking with your significant other!

Oh wait, nope...that's suppression.  Sorry.</htmltext>
<tokenext>Nah , you cure it by taking walks along the beach , climbing rocks , and mountain biking with your significant other !
Oh wait , nope...that 's suppression .
Sorry .</tokentext>
<sentencetext>Nah, you cure it by taking walks along the beach, climbing rocks, and mountain biking with your significant other!
Oh wait, nope...that's suppression.
Sorry.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562615</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28568017</id>
	<title>Re:Who is nuts enough to test effectiveness?</title>
	<author>ECCN</author>
	<datestamp>1246552800000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>If it makes it to phase II trials, I see street corner recruiting operations in Big Cities...</p><p>"Get this shot, we will pay you $100.00; come back once a month to have blood drawn, we will pay you $25.00"</p><p>It will be marketed toward the low income, homeless, 3rd tier of society types and active homosexuals.  They will have more people signing up than they can handle.</p><p>If it makes it to Phase III trials...    it is anybody's guess...  Perhaps, targeted toward people that have other terminal illnesses, using either the "help humanity" approach, or the "we will pay your surviving relatives $$$" approach.</p></htmltext>
<tokenext>If it makes it to phase II trials , I see street corner recruiting operations in Big Cities... " Get this shot , we will pay you $ 100.00 ; come back once a month to have blood drawn , we will pay you $ 25.00 " It will be marketed toward the low income , homeless , 3rd tier of society types and active homosexuals .
They will have more people signing up than they can handle.If it makes it to Phase III trials... it is anybody 's guess... Perhaps , targeted toward people that have other terminal illnesses , using either the " help humanity " approach , or the " we will pay your surviving relatives $ $ $ " approach .</tokentext>
<sentencetext>If it makes it to phase II trials, I see street corner recruiting operations in Big Cities..."Get this shot, we will pay you $100.00; come back once a month to have blood drawn, we will pay you $25.00"It will be marketed toward the low income, homeless, 3rd tier of society types and active homosexuals.
They will have more people signing up than they can handle.If it makes it to Phase III trials...    it is anybody's guess...  Perhaps, targeted toward people that have other terminal illnesses, using either the "help humanity" approach, or the "we will pay your surviving relatives $$$" approach.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563607</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563353</id>
	<title>Re:how do you test it?</title>
	<author>Anonymous</author>
	<datestamp>1246525380000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><blockquote><div><p>If I take the vaccine and I only sleep with my wife and in 10 years I'm HIV free does it work?</p></div></blockquote><p>Are you saying your wife is HIV positive?  Anyway, this is only phase I.  You're thinking of phase II.</p></div>
	</htmltext>
<tokenext>If I take the vaccine and I only sleep with my wife and in 10 years I 'm HIV free does it work ? Are you saying your wife is HIV positive ?
Anyway , this is only phase I. You 're thinking of phase II .</tokentext>
<sentencetext>If I take the vaccine and I only sleep with my wife and in 10 years I'm HIV free does it work?Are you saying your wife is HIV positive?
Anyway, this is only phase I.  You're thinking of phase II.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562789</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563307</id>
	<title>Re:how do you test it?</title>
	<author>Anonymous</author>
	<datestamp>1246525260000</datestamp>
	<modclass>Informativ</modclass>
	<modscore>2</modscore>
	<htmltext>Geez, can't people even be bothered to read the summary anymore? From the <b>summary</b>:<blockquote><div><p>Phase 1 human trials will check the safety of the vaccine on <b>HIV positive volunteers</b>.</p></div></blockquote><p>Presumably this is a therapeutic vaccine intended to equip the immune system to fight HIV before it trashes your immune system irreparably. I didn't bother to read the article (but I was able to finish the summary) so I wouldn't really know.</p></div>
	</htmltext>
<tokenext>Geez , ca n't people even be bothered to read the summary anymore ?
From the summary : Phase 1 human trials will check the safety of the vaccine on HIV positive volunteers.Presumably this is a therapeutic vaccine intended to equip the immune system to fight HIV before it trashes your immune system irreparably .
I did n't bother to read the article ( but I was able to finish the summary ) so I would n't really know .</tokentext>
<sentencetext>Geez, can't people even be bothered to read the summary anymore?
From the summary:Phase 1 human trials will check the safety of the vaccine on HIV positive volunteers.Presumably this is a therapeutic vaccine intended to equip the immune system to fight HIV before it trashes your immune system irreparably.
I didn't bother to read the article (but I was able to finish the summary) so I wouldn't really know.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562789</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28568197</id>
	<title>Re:Is this it?</title>
	<author>Anonymous</author>
	<datestamp>1246554300000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>A very minor nitpick: AIDS is Acquired Immune Deficiency or Immunodeficiency (depending on who you ask) Syndrome, not Auto-Immune Deficiency Syndrome (which might actually be a desirable thing).</p></htmltext>
<tokenext>A very minor nitpick : AIDS is Acquired Immune Deficiency or Immunodeficiency ( depending on who you ask ) Syndrome , not Auto-Immune Deficiency Syndrome ( which might actually be a desirable thing ) .</tokentext>
<sentencetext>A very minor nitpick: AIDS is Acquired Immune Deficiency or Immunodeficiency (depending on who you ask) Syndrome, not Auto-Immune Deficiency Syndrome (which might actually be a desirable thing).</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562981</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565217</id>
	<title>Re:Cue objections from the religious right:</title>
	<author>Anonymous</author>
	<datestamp>1246532820000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>Umm I think that makes you just a normal Christian, it is the conservative part that connotates all the other whacko shit.</p></htmltext>
<tokenext>Umm I think that makes you just a normal Christian , it is the conservative part that connotates all the other whacko shit .</tokentext>
<sentencetext>Umm I think that makes you just a normal Christian, it is the conservative part that connotates all the other whacko shit.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562683</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28570893</id>
	<title>Re:No Optimism on HIV</title>
	<author>RiotingPacifist</author>
	<datestamp>1246631220000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>b) requires cheap, easy tests and a change in attitude towards stds.</p></htmltext>
<tokenext>b ) requires cheap , easy tests and a change in attitude towards stds .</tokentext>
<sentencetext>b) requires cheap, easy tests and a change in attitude towards stds.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563651</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564261</id>
	<title>Re:Is this it?</title>
	<author>Anonymous</author>
	<datestamp>1246528740000</datestamp>
	<modclass>Informativ</modclass>
	<modscore>2</modscore>
	<htmltext><p>This is a phase I test.</p><p>The huge one is phase III</p><p>http://www.iavi.org/RESEARCH-DEVELOPMENT/DEVELOPMENT-CYCLE/Pages/review-process.aspx</p><p>Other vaccines passed phase I and failed after that.</p><p>These are good news because scientists doesn't start human trials if they don't feel good about the vaccine developed but it isn't the time to celebrate yet.</p></htmltext>
<tokenext>This is a phase I test.The huge one is phase IIIhttp : //www.iavi.org/RESEARCH-DEVELOPMENT/DEVELOPMENT-CYCLE/Pages/review-process.aspxOther vaccines passed phase I and failed after that.These are good news because scientists does n't start human trials if they do n't feel good about the vaccine developed but it is n't the time to celebrate yet .</tokentext>
<sentencetext>This is a phase I test.The huge one is phase IIIhttp://www.iavi.org/RESEARCH-DEVELOPMENT/DEVELOPMENT-CYCLE/Pages/review-process.aspxOther vaccines passed phase I and failed after that.These are good news because scientists doesn't start human trials if they don't feel good about the vaccine developed but it isn't the time to celebrate yet.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562707</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28566201</id>
	<title>Re:how do you test it?</title>
	<author>duffel</author>
	<datestamp>1246538460000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>Only if you inject someone else. Dr Barry Marshal jointly won the Nobel prize for Medicine in no small part for infecting himself with Helicobacter pylori. Different league of disease, true, but infecting <em>someone</em> isn't necessarily out of the question. I wouldn't be at all surprised if the researcher that proves the effectiveness of this vaccine by injecting themselves with HIV also won a nobel prize, given how many people die from AIDS.</p></htmltext>
<tokenext>Only if you inject someone else .
Dr Barry Marshal jointly won the Nobel prize for Medicine in no small part for infecting himself with Helicobacter pylori .
Different league of disease , true , but infecting someone is n't necessarily out of the question .
I would n't be at all surprised if the researcher that proves the effectiveness of this vaccine by injecting themselves with HIV also won a nobel prize , given how many people die from AIDS .</tokentext>
<sentencetext>Only if you inject someone else.
Dr Barry Marshal jointly won the Nobel prize for Medicine in no small part for infecting himself with Helicobacter pylori.
Different league of disease, true, but infecting someone isn't necessarily out of the question.
I wouldn't be at all surprised if the researcher that proves the effectiveness of this vaccine by injecting themselves with HIV also won a nobel prize, given how many people die from AIDS.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563335</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563413</id>
	<title>Re:Yay!</title>
	<author>TheRaven64</author>
	<datestamp>1246525620000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>2</modscore>
	<htmltext>Thalidomide.</htmltext>
<tokenext>Thalidomide .</tokentext>
<sentencetext>Thalidomide.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562831</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564519</id>
	<title>Re:No Optimism on HIV</title>
	<author>greymond</author>
	<datestamp>1246529880000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>um not that I don't agree with some of what you're saying but 3\% of DC's population versus 3\% of Uganda and/or Kenya's population is like comparing 3\% of one apple to 3\% of a barrel of apples...</p></htmltext>
<tokenext>um not that I do n't agree with some of what you 're saying but 3 \ % of DC 's population versus 3 \ % of Uganda and/or Kenya 's population is like comparing 3 \ % of one apple to 3 \ % of a barrel of apples.. .</tokentext>
<sentencetext>um not that I don't agree with some of what you're saying but 3\% of DC's population versus 3\% of Uganda and/or Kenya's population is like comparing 3\% of one apple to 3\% of a barrel of apples...</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562905</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565937</id>
	<title>Phase 3.</title>
	<author>Anonymous</author>
	<datestamp>1246536900000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>Phase 3 = Profit!</p></htmltext>
<tokenext>Phase 3 = Profit !</tokentext>
<sentencetext>Phase 3 = Profit!</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28577469</id>
	<title>Re:Test on</title>
	<author>quenda</author>
	<datestamp>1246639140000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><div class="quote"><p>Phase 1 human trials will check the safety of the vaccine on HIV positive volunteers</p></div><p>Sensible move. They should tested <a href="http://en.wikipedia.org/wiki/TGN1412" title="wikipedia.org">TGN1412</a> [wikipedia.org]on an AIDs patient first.</p></div>
	</htmltext>
<tokenext>Phase 1 human trials will check the safety of the vaccine on HIV positive volunteersSensible move .
They should tested TGN1412 [ wikipedia.org ] on an AIDs patient first .</tokentext>
<sentencetext>Phase 1 human trials will check the safety of the vaccine on HIV positive volunteersSensible move.
They should tested TGN1412 [wikipedia.org]on an AIDs patient first.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562583</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28567695</id>
	<title>Re:Cue objections from the religious right:</title>
	<author>Anonymous</author>
	<datestamp>1246549740000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>Why is this getting modded Interesting? Is it really that interesting that there are exceptions to every rule? By and large, though, conservative Christians don't believe in evolution and are against gay marriage. But this isn't really news either.</htmltext>
<tokenext>Why is this getting modded Interesting ?
Is it really that interesting that there are exceptions to every rule ?
By and large , though , conservative Christians do n't believe in evolution and are against gay marriage .
But this is n't really news either .</tokentext>
<sentencetext>Why is this getting modded Interesting?
Is it really that interesting that there are exceptions to every rule?
By and large, though, conservative Christians don't believe in evolution and are against gay marriage.
But this isn't really news either.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562683</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562877</id>
	<title>Re:Is this it?</title>
	<author>Anonymous</author>
	<datestamp>1246567080000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>5</modscore>
	<htmltext><p>I assume that depends on the level of immunity it provides.  Are we talking Flu Vaccine or Small Pox vaccine level of protection?</p></htmltext>
<tokenext>I assume that depends on the level of immunity it provides .
Are we talking Flu Vaccine or Small Pox vaccine level of protection ?</tokentext>
<sentencetext>I assume that depends on the level of immunity it provides.
Are we talking Flu Vaccine or Small Pox vaccine level of protection?</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562707</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563061</id>
	<title>Re:Which is It?</title>
	<author>Anonymous</author>
	<datestamp>1246567680000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p><div class="quote"><p>Think of the confusion: Person with AIDS gets vaccine and thinks it's okay to have unprotected sex willy-nilly.</p></div><p>Having sex all willy-nilly is just plain silly. Just ask Milli Vanilli or Hillbilly Bildilli.</p></div>
	</htmltext>
<tokenext>Think of the confusion : Person with AIDS gets vaccine and thinks it 's okay to have unprotected sex willy-nilly.Having sex all willy-nilly is just plain silly .
Just ask Milli Vanilli or Hillbilly Bildilli .</tokentext>
<sentencetext>Think of the confusion: Person with AIDS gets vaccine and thinks it's okay to have unprotected sex willy-nilly.Having sex all willy-nilly is just plain silly.
Just ask Milli Vanilli or Hillbilly Bildilli.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562527</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28572737</id>
	<title>Re:Which is It?</title>
	<author>Anonymous</author>
	<datestamp>1246642380000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>I think GP was just arguing against the common conflation of the infection with the disease. </p><p><div class="quote"><p>separate, though related</p></div><p>doesn't sound like a wacky denialist. It's very important to point out that being HIV+ doesn't mean you have symptoms, let alone visible ones, and that getting infected isn't a death sentence anymore if you can afford the treatment. The delusion that it's safe to bareback as long as the partner "looks healthy" is still rampant among gays, even if we should really know better.</p></div>
	</htmltext>
<tokenext>I think GP was just arguing against the common conflation of the infection with the disease .
separate , though relateddoes n't sound like a wacky denialist .
It 's very important to point out that being HIV + does n't mean you have symptoms , let alone visible ones , and that getting infected is n't a death sentence anymore if you can afford the treatment .
The delusion that it 's safe to bareback as long as the partner " looks healthy " is still rampant among gays , even if we should really know better .</tokentext>
<sentencetext>I think GP was just arguing against the common conflation of the infection with the disease.
separate, though relateddoesn't sound like a wacky denialist.
It's very important to point out that being HIV+ doesn't mean you have symptoms, let alone visible ones, and that getting infected isn't a death sentence anymore if you can afford the treatment.
The delusion that it's safe to bareback as long as the partner "looks healthy" is still rampant among gays, even if we should really know better.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562931</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565109</id>
	<title>Re:Which is It?</title>
	<author>nedlohs</author>
	<datestamp>1246532280000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>No way!</p><p>Vaccines just stop you getting the thing, rather than curing you once you already have it.</p><p>Who knew?!?</p><p>It's pretty obviously (without even RTFA) a vaccine for HIV with the intention of hence stopping you getting AIDS if you get exposed to HIV later. Like every other bloody vaccine in the universe.</p><p>You confusion is stupid. No one with AIDS would be given the vaccine since it's pointless at that point. Even if they were why would they think it would stop them infecting others? Do people who get flu shots start coughing on everyone they meet???</p></htmltext>
<tokenext>No way ! Vaccines just stop you getting the thing , rather than curing you once you already have it.Who knew ? !
? It 's pretty obviously ( without even RTFA ) a vaccine for HIV with the intention of hence stopping you getting AIDS if you get exposed to HIV later .
Like every other bloody vaccine in the universe.You confusion is stupid .
No one with AIDS would be given the vaccine since it 's pointless at that point .
Even if they were why would they think it would stop them infecting others ?
Do people who get flu shots start coughing on everyone they meet ? ?
?</tokentext>
<sentencetext>No way!Vaccines just stop you getting the thing, rather than curing you once you already have it.Who knew?!
?It's pretty obviously (without even RTFA) a vaccine for HIV with the intention of hence stopping you getting AIDS if you get exposed to HIV later.
Like every other bloody vaccine in the universe.You confusion is stupid.
No one with AIDS would be given the vaccine since it's pointless at that point.
Even if they were why would they think it would stop them infecting others?
Do people who get flu shots start coughing on everyone they meet??
?</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562527</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28570239</id>
	<title>Re:Which is It?</title>
	<author>ciderVisor</author>
	<datestamp>1246625760000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><div class="quote"><p>Do people who get flu shots start coughing on everyone they meet???</p></div><p>That's unexpectorated behaviour.</p></div>
	</htmltext>
<tokenext>Do people who get flu shots start coughing on everyone they meet ? ?
? That 's unexpectorated behaviour .</tokentext>
<sentencetext>Do people who get flu shots start coughing on everyone they meet??
?That's unexpectorated behaviour.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28565109</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28566267</id>
	<title>Re:Cue objections from the religious right:</title>
	<author>Anonymous</author>
	<datestamp>1246538760000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>Wouldn't that make you a Christian and NOT a conservative Christian?  I mean, I thought the whole point of using the "conservative" qualifier was to distinguish the fundamentalists from the general Christian population.</p></htmltext>
<tokenext>Would n't that make you a Christian and NOT a conservative Christian ?
I mean , I thought the whole point of using the " conservative " qualifier was to distinguish the fundamentalists from the general Christian population .</tokentext>
<sentencetext>Wouldn't that make you a Christian and NOT a conservative Christian?
I mean, I thought the whole point of using the "conservative" qualifier was to distinguish the fundamentalists from the general Christian population.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562683</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563351</id>
	<title>Re:how do you test it?</title>
	<author>Anonymous</author>
	<datestamp>1246525380000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>The original smallpox immunization test was run on an orphan girl by exposing her to smallpox after she'd been immunized.  Practices have been changed since then.</p><p> The 'ultimate' endpoint for a vaccine trials compares two large groups, one vaccinated, one not, over a long period of time and compare to infection rates.  Since volunteers are assigned randomly to one group, if the overall rates are lower in the vaccine group than the control, and the difference holds up to statistical analysis, you have good evidence it works.  The signal is weak, meaning the trials have to be long and large to tell the difference.  They are expensive.</p><p>In the early stages of trials, you're looking more directly for markers that the vaccine might be working--are you stimulating antibody production of the type you intended to do?  These are smaller and cheaper, and can at least tell you it won't work.</p></htmltext>
<tokenext>The original smallpox immunization test was run on an orphan girl by exposing her to smallpox after she 'd been immunized .
Practices have been changed since then .
The 'ultimate ' endpoint for a vaccine trials compares two large groups , one vaccinated , one not , over a long period of time and compare to infection rates .
Since volunteers are assigned randomly to one group , if the overall rates are lower in the vaccine group than the control , and the difference holds up to statistical analysis , you have good evidence it works .
The signal is weak , meaning the trials have to be long and large to tell the difference .
They are expensive.In the early stages of trials , you 're looking more directly for markers that the vaccine might be working--are you stimulating antibody production of the type you intended to do ?
These are smaller and cheaper , and can at least tell you it wo n't work .</tokentext>
<sentencetext>The original smallpox immunization test was run on an orphan girl by exposing her to smallpox after she'd been immunized.
Practices have been changed since then.
The 'ultimate' endpoint for a vaccine trials compares two large groups, one vaccinated, one not, over a long period of time and compare to infection rates.
Since volunteers are assigned randomly to one group, if the overall rates are lower in the vaccine group than the control, and the difference holds up to statistical analysis, you have good evidence it works.
The signal is weak, meaning the trials have to be long and large to tell the difference.
They are expensive.In the early stages of trials, you're looking more directly for markers that the vaccine might be working--are you stimulating antibody production of the type you intended to do?
These are smaller and cheaper, and can at least tell you it won't work.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562789</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28581573</id>
	<title>Re:Which is It?</title>
	<author>Anonymous</author>
	<datestamp>1246734480000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext>You are an idiot.  It's obviously a vaccine to prevent HIV infection and AIDS, and not a cure. The only one creating the confusion is you. Once again another anti-sex idiot trying to confuse people.

And yes, HIV and AIDS are directly related. HIV is the name of the virus, and AIDS is the name of the disease it causes. Go back to 4chan, ass.</htmltext>
<tokenext>You are an idiot .
It 's obviously a vaccine to prevent HIV infection and AIDS , and not a cure .
The only one creating the confusion is you .
Once again another anti-sex idiot trying to confuse people .
And yes , HIV and AIDS are directly related .
HIV is the name of the virus , and AIDS is the name of the disease it causes .
Go back to 4chan , ass .</tokentext>
<sentencetext>You are an idiot.
It's obviously a vaccine to prevent HIV infection and AIDS, and not a cure.
The only one creating the confusion is you.
Once again another anti-sex idiot trying to confuse people.
And yes, HIV and AIDS are directly related.
HIV is the name of the virus, and AIDS is the name of the disease it causes.
Go back to 4chan, ass.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562527</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564681</id>
	<title>Re:Who is nuts enough to test effectiveness?</title>
	<author>markringen</author>
	<datestamp>1246530540000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>your already dead.
how much deader can u get?</htmltext>
<tokenext>your already dead .
how much deader can u get ?</tokentext>
<sentencetext>your already dead.
how much deader can u get?</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563607</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28573143</id>
	<title>ZOMG Zombies!</title>
	<author>werfu</author>
	<datestamp>1246644840000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>Hoo shit, that's it, when is it gonna start? I need to grab a shutgun and a lot of ammo before first people get vaccined!!!!</htmltext>
<tokenext>Hoo shit , that 's it , when is it gon na start ?
I need to grab a shutgun and a lot of ammo before first people get vaccined ! ! !
!</tokentext>
<sentencetext>Hoo shit, that's it, when is it gonna start?
I need to grab a shutgun and a lot of ammo before first people get vaccined!!!
!</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28567093</id>
	<title>Re:Is this it?</title>
	<author>moosesocks</author>
	<datestamp>1246544460000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>This is indeed true.  Most notably, HIV/AIDS is <i>much</i> less prevalent in the gay community than it was 10 years ago, and most  now tend to be extremely cautious about who they sleep with.</p><p>Education and comprehensive testing are by far the two most effective weapons against sexually transmitted infections.</p></htmltext>
<tokenext>This is indeed true .
Most notably , HIV/AIDS is much less prevalent in the gay community than it was 10 years ago , and most now tend to be extremely cautious about who they sleep with.Education and comprehensive testing are by far the two most effective weapons against sexually transmitted infections .</tokentext>
<sentencetext>This is indeed true.
Most notably, HIV/AIDS is much less prevalent in the gay community than it was 10 years ago, and most  now tend to be extremely cautious about who they sleep with.Education and comprehensive testing are by far the two most effective weapons against sexually transmitted infections.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564107</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563319</id>
	<title>Re:No Optimism on HIV</title>
	<author>TheMohel</author>
	<datestamp>1246525320000</datestamp>
	<modclass>Informativ</modclass>
	<modscore>2</modscore>
	<htmltext><p>Unfortunately (OK, it's not unfortunate at all, actually), option #1 isn't just taboo, it's impossible in any human society. Even if we had a completely accurate test (which we certainly do NOT have), and even if you could somehow prevent all positive contacts from continuing their infectious behavior (and I'm not sure anything short of summary execution would be reliable), you'd still have leakers, avoiders, corruption, and resistance. Not even North Korea has managed to avoid HIV, although they're close, at least by report. Largely, I suspect, because summary execution is a routine thing for them.
</p><p>Option #2 is science fiction for now. The genetic resistance to HIV is conferred by the lack of a particular cell-surface receptor, so you'd have to find a way to effectively eliminate that piece of genetic material from every genome in the body. And since T cells are quite long-lived, you'd have to mess with a lot of quiescent DNA to do it. Maybe some day, but not soon.
</p><p>Which leaves vaccination. I'm in agreement with your skepticism on this one, not because it's impossible but because HIV, due to its unique targeting system, has been very intractable. You do have to target relatively stable regions of its proteins or its DNA, but this isn't unique to HIV, and we've solved it with polyvalent vaccines elsewhere (think Menactra, or the recent HPV vaccine, or even the flu shot). HIV is a pretty wimpy virus from a spread perspective, so a good polyvalent vaccine would seem possible. The problem is practical immunogenicity, and that's the issue that has torpedoed previous vaccines.</p></htmltext>
<tokenext>Unfortunately ( OK , it 's not unfortunate at all , actually ) , option # 1 is n't just taboo , it 's impossible in any human society .
Even if we had a completely accurate test ( which we certainly do NOT have ) , and even if you could somehow prevent all positive contacts from continuing their infectious behavior ( and I 'm not sure anything short of summary execution would be reliable ) , you 'd still have leakers , avoiders , corruption , and resistance .
Not even North Korea has managed to avoid HIV , although they 're close , at least by report .
Largely , I suspect , because summary execution is a routine thing for them .
Option # 2 is science fiction for now .
The genetic resistance to HIV is conferred by the lack of a particular cell-surface receptor , so you 'd have to find a way to effectively eliminate that piece of genetic material from every genome in the body .
And since T cells are quite long-lived , you 'd have to mess with a lot of quiescent DNA to do it .
Maybe some day , but not soon .
Which leaves vaccination .
I 'm in agreement with your skepticism on this one , not because it 's impossible but because HIV , due to its unique targeting system , has been very intractable .
You do have to target relatively stable regions of its proteins or its DNA , but this is n't unique to HIV , and we 've solved it with polyvalent vaccines elsewhere ( think Menactra , or the recent HPV vaccine , or even the flu shot ) .
HIV is a pretty wimpy virus from a spread perspective , so a good polyvalent vaccine would seem possible .
The problem is practical immunogenicity , and that 's the issue that has torpedoed previous vaccines .</tokentext>
<sentencetext>Unfortunately (OK, it's not unfortunate at all, actually), option #1 isn't just taboo, it's impossible in any human society.
Even if we had a completely accurate test (which we certainly do NOT have), and even if you could somehow prevent all positive contacts from continuing their infectious behavior (and I'm not sure anything short of summary execution would be reliable), you'd still have leakers, avoiders, corruption, and resistance.
Not even North Korea has managed to avoid HIV, although they're close, at least by report.
Largely, I suspect, because summary execution is a routine thing for them.
Option #2 is science fiction for now.
The genetic resistance to HIV is conferred by the lack of a particular cell-surface receptor, so you'd have to find a way to effectively eliminate that piece of genetic material from every genome in the body.
And since T cells are quite long-lived, you'd have to mess with a lot of quiescent DNA to do it.
Maybe some day, but not soon.
Which leaves vaccination.
I'm in agreement with your skepticism on this one, not because it's impossible but because HIV, due to its unique targeting system, has been very intractable.
You do have to target relatively stable regions of its proteins or its DNA, but this isn't unique to HIV, and we've solved it with polyvalent vaccines elsewhere (think Menactra, or the recent HPV vaccine, or even the flu shot).
HIV is a pretty wimpy virus from a spread perspective, so a good polyvalent vaccine would seem possible.
The problem is practical immunogenicity, and that's the issue that has torpedoed previous vaccines.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562905</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562527</id>
	<title>Which is It?</title>
	<author>Anonymous</author>
	<datestamp>1246566180000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>5</modscore>
	<htmltext><p>Is this a vaccine for the virus, as one with half a brain would assume?</p><p>Or is this a magic serum that cures you of AIDS while not dealing with HIV?</p><p>HIV/AIDS is stupid.<br>HIV and AIDS are separate, though related, things.</p><p>Think of the confusion:<br>Person with AIDS gets vaccine and thinks it's okay to have unprotected sex willy-nilly.</p></htmltext>
<tokenext>Is this a vaccine for the virus , as one with half a brain would assume ? Or is this a magic serum that cures you of AIDS while not dealing with HIV ? HIV/AIDS is stupid.HIV and AIDS are separate , though related , things.Think of the confusion : Person with AIDS gets vaccine and thinks it 's okay to have unprotected sex willy-nilly .</tokentext>
<sentencetext>Is this a vaccine for the virus, as one with half a brain would assume?Or is this a magic serum that cures you of AIDS while not dealing with HIV?HIV/AIDS is stupid.HIV and AIDS are separate, though related, things.Think of the confusion:Person with AIDS gets vaccine and thinks it's okay to have unprotected sex willy-nilly.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28564695</id>
	<title>Re:Which is It?</title>
	<author>slapout</author>
	<datestamp>1246530600000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>"HIV/AIDS"</p><p>Have you ever heard the media mention the term "HIV" without immediately following it with "the virus that causes AIDS"? It's the media that's bonded those terms.</p></htmltext>
<tokenext>" HIV/AIDS " Have you ever heard the media mention the term " HIV " without immediately following it with " the virus that causes AIDS " ?
It 's the media that 's bonded those terms .</tokentext>
<sentencetext>"HIV/AIDS"Have you ever heard the media mention the term "HIV" without immediately following it with "the virus that causes AIDS"?
It's the media that's bonded those terms.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562527</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28563469</id>
	<title>Re:No Optimism on HIV</title>
	<author>ae1294</author>
	<datestamp>1246525740000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><div class="quote"><p>The only way to eradicate this virus is either</p> </div><p>You forgot one option. We can nuke the site from orbit as it's really the only way to be sure...It's DC after all...</p></div>
	</htmltext>
<tokenext>The only way to eradicate this virus is either You forgot one option .
We can nuke the site from orbit as it 's really the only way to be sure...It 's DC after all.. .</tokentext>
<sentencetext>The only way to eradicate this virus is either You forgot one option.
We can nuke the site from orbit as it's really the only way to be sure...It's DC after all...
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_07_02_192249.28562905</parent>
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