<article>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#article09_10_23_1333228</id>
	<title>Virus-Like Particles May Mean Speedier Flu Vaccines</title>
	<author>kdawson</author>
	<datestamp>1256310600000</datestamp>
	<htmltext>We've been talking a lot lately about <a href="//slashdot.org/story/09/10/20/1657217/Nationwide-Shortage-In-Supply-of-Swine-Flu-Vaccine">flu</a> <a href="//science.slashdot.org/story/09/10/17/1651206/On-the-Efficacy-of-Flu-Vaccine?from=rss">vaccines</a>. Now an anonymous reader sends us to a Technology Review piece on <a href="http://www.technologyreview.com/biomedicine/23782/">two human trials involving so-called virus-like particle vaccines</a>, which promise to be much faster to churn out than traditional vaccines. (Here's a <a href="http://www.technologyreview.com/printer\_friendly\_article.aspx?id=23782&amp;channel=biomedicine&amp;section=">single-page version</a> but without the useful illustration.) VLP vaccines use a protein shell, grown in either plant or insect cells, that look just like real viruses to the body's immune system but that contain no influenza RNA genetic material. A company called Medicago grows its VLPs in transgenic tobacco plants, while another called Novavax uses "immortalized" cells taken from caterpillars. Providing they pass safety muster, both techniques should be able to produce an influenza vaccine more quickly than current methods, using just the DNA of the virus.</htmltext>
<tokenext>We 've been talking a lot lately about flu vaccines .
Now an anonymous reader sends us to a Technology Review piece on two human trials involving so-called virus-like particle vaccines , which promise to be much faster to churn out than traditional vaccines .
( Here 's a single-page version but without the useful illustration .
) VLP vaccines use a protein shell , grown in either plant or insect cells , that look just like real viruses to the body 's immune system but that contain no influenza RNA genetic material .
A company called Medicago grows its VLPs in transgenic tobacco plants , while another called Novavax uses " immortalized " cells taken from caterpillars .
Providing they pass safety muster , both techniques should be able to produce an influenza vaccine more quickly than current methods , using just the DNA of the virus .</tokentext>
<sentencetext>We've been talking a lot lately about flu vaccines.
Now an anonymous reader sends us to a Technology Review piece on two human trials involving so-called virus-like particle vaccines, which promise to be much faster to churn out than traditional vaccines.
(Here's a single-page version but without the useful illustration.
) VLP vaccines use a protein shell, grown in either plant or insect cells, that look just like real viruses to the body's immune system but that contain no influenza RNA genetic material.
A company called Medicago grows its VLPs in transgenic tobacco plants, while another called Novavax uses "immortalized" cells taken from caterpillars.
Providing they pass safety muster, both techniques should be able to produce an influenza vaccine more quickly than current methods, using just the DNA of the virus.</sentencetext>
</article>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846401</id>
	<title>vaccine manufacturers caught with pants down</title>
	<author>sumthinboutjesus</author>
	<datestamp>1256314680000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>As a future healthcare provider, I certainly hope that vaccines like these will be proven safe and effective.  Their promise lies in the ability for the production of vaccines against the dominant strains in a much quicker manner.  If we had these methods approved for the current flu season, the industry wouldn't have been caught with its pants down when the H1N1 strain became dominant and hit much more quickly than planned.  The vaccines were targeted to be ready for about a month or two from now, and the virus has hit much harder much sooner than anticipated.  If these techniques take off, hopefully this situation can be mostly avoided in the future.</htmltext>
<tokenext>As a future healthcare provider , I certainly hope that vaccines like these will be proven safe and effective .
Their promise lies in the ability for the production of vaccines against the dominant strains in a much quicker manner .
If we had these methods approved for the current flu season , the industry would n't have been caught with its pants down when the H1N1 strain became dominant and hit much more quickly than planned .
The vaccines were targeted to be ready for about a month or two from now , and the virus has hit much harder much sooner than anticipated .
If these techniques take off , hopefully this situation can be mostly avoided in the future .</tokentext>
<sentencetext>As a future healthcare provider, I certainly hope that vaccines like these will be proven safe and effective.
Their promise lies in the ability for the production of vaccines against the dominant strains in a much quicker manner.
If we had these methods approved for the current flu season, the industry wouldn't have been caught with its pants down when the H1N1 strain became dominant and hit much more quickly than planned.
The vaccines were targeted to be ready for about a month or two from now, and the virus has hit much harder much sooner than anticipated.
If these techniques take off, hopefully this situation can be mostly avoided in the future.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29847565</id>
	<title>Nice to see this here</title>
	<author>jeffasselin</author>
	<datestamp>1256320380000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>I've done some IT contracting work for Medicago for a few years, they're a local enterprise, and I know the people behind the technology and I know their installations quite well. It's quite impressive, and I know they're now set on human testing after years of work and animal tests. Glad to see them getting some attention. I think this kind of technology is the future of medicine production.</p></htmltext>
<tokenext>I 've done some IT contracting work for Medicago for a few years , they 're a local enterprise , and I know the people behind the technology and I know their installations quite well .
It 's quite impressive , and I know they 're now set on human testing after years of work and animal tests .
Glad to see them getting some attention .
I think this kind of technology is the future of medicine production .</tokentext>
<sentencetext>I've done some IT contracting work for Medicago for a few years, they're a local enterprise, and I know the people behind the technology and I know their installations quite well.
It's quite impressive, and I know they're now set on human testing after years of work and animal tests.
Glad to see them getting some attention.
I think this kind of technology is the future of medicine production.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29847341</id>
	<title>Re:Typical big media...</title>
	<author>FatdogHaiku</author>
	<datestamp>1256319420000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><div class="quote"><p>You guys are running around producing Immortal caterpillars and noone let me know? Bastards!</p></div><p>I can't wait for the final showdown where they fight with tiny little katanas and broadswords. It's going to be really tough on the little guys because it's hard to tell if you just cut off your opponent's head or only gave him a free Brazilian Butt Lift... There can be only one.</p></div>
	</htmltext>
<tokenext>You guys are running around producing Immortal caterpillars and noone let me know ?
Bastards ! I ca n't wait for the final showdown where they fight with tiny little katanas and broadswords .
It 's going to be really tough on the little guys because it 's hard to tell if you just cut off your opponent 's head or only gave him a free Brazilian Butt Lift... There can be only one .</tokentext>
<sentencetext>You guys are running around producing Immortal caterpillars and noone let me know?
Bastards!I can't wait for the final showdown where they fight with tiny little katanas and broadswords.
It's going to be really tough on the little guys because it's hard to tell if you just cut off your opponent's head or only gave him a free Brazilian Butt Lift... There can be only one.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846361</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29847533</id>
	<title>production in insect cells has advantages</title>
	<author>airuck</author>
	<datestamp>1256320200000</datestamp>
	<modclass>Interestin</modclass>
	<modscore>2</modscore>
	<htmltext><p>One great advantage in using insect cell lines is that they do not require serum to grow, which is both costly and open to the risk of transmitting zoonotic pathogens. Insect cells can also be more robust than mammalian cells in large scale fermentation conditions.</p></htmltext>
<tokenext>One great advantage in using insect cell lines is that they do not require serum to grow , which is both costly and open to the risk of transmitting zoonotic pathogens .
Insect cells can also be more robust than mammalian cells in large scale fermentation conditions .</tokentext>
<sentencetext>One great advantage in using insect cell lines is that they do not require serum to grow, which is both costly and open to the risk of transmitting zoonotic pathogens.
Insect cells can also be more robust than mammalian cells in large scale fermentation conditions.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846867</id>
	<title>Re:I wonder...</title>
	<author>crmarvin42</author>
	<datestamp>1256317020000</datestamp>
	<modclass>Informativ</modclass>
	<modscore>3</modscore>
	<htmltext>This solution would probably require much higher doses than current vaccines do, but it would probably be safer and faster.<br> <br>The flu at least is an RNA virus, but the function of the genetic material is for the replication of the virus after it has infected a cell.  When it is not actively infecting a cell the DNA/RNA is completely dormant within the viral coat, thus the debate over whether viruses are alive or not.  There is no metabolic activity in the absense of a host cell to infect.<br> <br>The shell or viral coat is primarily what the immune system recognizes when fighting a viral infection.  That is why killed vaccines work.  They don't work as well as modified live vaccines (generally) because you don't get the first couple of generations of viral replication (at a slower rate than the wildtype virus) that trigger a much stronger immune response.  Viral RNA can also trigger immune response, but the RNA needs to be processed by an antigen presenting cell such as an infected cell or a phagocyte.  <br> <br>It actually works the same way with certain bacteria.  Researchers will frequently inject LPS (lipopolysaccharide) into animals to simulate a bacterial infection, because bacteria have LPS on their surfaces and their are immune systems designed to recognize this ubiquitious bacterial component.<br> <br>I'm not sure about separate shells, but I do know that many (all?) viruses have several different proteins involved in making the shell, and that changes in which proteins are present will change the antigenic profile of the virus.</htmltext>
<tokenext>This solution would probably require much higher doses than current vaccines do , but it would probably be safer and faster .
The flu at least is an RNA virus , but the function of the genetic material is for the replication of the virus after it has infected a cell .
When it is not actively infecting a cell the DNA/RNA is completely dormant within the viral coat , thus the debate over whether viruses are alive or not .
There is no metabolic activity in the absense of a host cell to infect .
The shell or viral coat is primarily what the immune system recognizes when fighting a viral infection .
That is why killed vaccines work .
They do n't work as well as modified live vaccines ( generally ) because you do n't get the first couple of generations of viral replication ( at a slower rate than the wildtype virus ) that trigger a much stronger immune response .
Viral RNA can also trigger immune response , but the RNA needs to be processed by an antigen presenting cell such as an infected cell or a phagocyte .
It actually works the same way with certain bacteria .
Researchers will frequently inject LPS ( lipopolysaccharide ) into animals to simulate a bacterial infection , because bacteria have LPS on their surfaces and their are immune systems designed to recognize this ubiquitious bacterial component .
I 'm not sure about separate shells , but I do know that many ( all ?
) viruses have several different proteins involved in making the shell , and that changes in which proteins are present will change the antigenic profile of the virus .</tokentext>
<sentencetext>This solution would probably require much higher doses than current vaccines do, but it would probably be safer and faster.
The flu at least is an RNA virus, but the function of the genetic material is for the replication of the virus after it has infected a cell.
When it is not actively infecting a cell the DNA/RNA is completely dormant within the viral coat, thus the debate over whether viruses are alive or not.
There is no metabolic activity in the absense of a host cell to infect.
The shell or viral coat is primarily what the immune system recognizes when fighting a viral infection.
That is why killed vaccines work.
They don't work as well as modified live vaccines (generally) because you don't get the first couple of generations of viral replication (at a slower rate than the wildtype virus) that trigger a much stronger immune response.
Viral RNA can also trigger immune response, but the RNA needs to be processed by an antigen presenting cell such as an infected cell or a phagocyte.
It actually works the same way with certain bacteria.
Researchers will frequently inject LPS (lipopolysaccharide) into animals to simulate a bacterial infection, because bacteria have LPS on their surfaces and their are immune systems designed to recognize this ubiquitious bacterial component.
I'm not sure about separate shells, but I do know that many (all?
) viruses have several different proteins involved in making the shell, and that changes in which proteins are present will change the antigenic profile of the virus.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846417</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29848577</id>
	<title>Re:I wonder...</title>
	<author>nietsch</author>
	<datestamp>1256323980000</datestamp>
	<modclass>Interestin</modclass>
	<modscore>2</modscore>
	<htmltext><p>I am a Biologist, please allow me to answer:<br>Yes the DNA or RNA has a function: to make more virus. immune reactions work on anything the immune system recognises, and because the immune system is built with protein, it is mostly protein it recognises. Naked DNA or RNA in the bloodstream is quickly mopped up, so you do not need specific immunity.</p><p>Vaccination does not trigger an immediate response if you have never seen the antigen before (and if you have, the vaccination is needless and poses a risk). It takes some time to mount an immune response, about as long as 'the flu' lasts. once this response is established, your immune system 'remembers' it. A next exposure to the antigen will see a much quicker response to the antigen, and the second exposure will also reinforce your long term immunity. Read up on immunity if you still don't trust it, this is basically just how it works.</p><p>The flu virus evolves a new shell almost every season, exactly because the immune system reacts on its outer envelope. 'They' have no system to switch between different env genes, as you'd need a lot of overhead for that. Having a lot of mutations between each generation and letting basic evolution take its course works much more efficiently.</p></htmltext>
<tokenext>I am a Biologist , please allow me to answer : Yes the DNA or RNA has a function : to make more virus .
immune reactions work on anything the immune system recognises , and because the immune system is built with protein , it is mostly protein it recognises .
Naked DNA or RNA in the bloodstream is quickly mopped up , so you do not need specific immunity.Vaccination does not trigger an immediate response if you have never seen the antigen before ( and if you have , the vaccination is needless and poses a risk ) .
It takes some time to mount an immune response , about as long as 'the flu ' lasts .
once this response is established , your immune system 'remembers ' it .
A next exposure to the antigen will see a much quicker response to the antigen , and the second exposure will also reinforce your long term immunity .
Read up on immunity if you still do n't trust it , this is basically just how it works.The flu virus evolves a new shell almost every season , exactly because the immune system reacts on its outer envelope .
'They ' have no system to switch between different env genes , as you 'd need a lot of overhead for that .
Having a lot of mutations between each generation and letting basic evolution take its course works much more efficiently .</tokentext>
<sentencetext>I am a Biologist, please allow me to answer:Yes the DNA or RNA has a function: to make more virus.
immune reactions work on anything the immune system recognises, and because the immune system is built with protein, it is mostly protein it recognises.
Naked DNA or RNA in the bloodstream is quickly mopped up, so you do not need specific immunity.Vaccination does not trigger an immediate response if you have never seen the antigen before (and if you have, the vaccination is needless and poses a risk).
It takes some time to mount an immune response, about as long as 'the flu' lasts.
once this response is established, your immune system 'remembers' it.
A next exposure to the antigen will see a much quicker response to the antigen, and the second exposure will also reinforce your long term immunity.
Read up on immunity if you still don't trust it, this is basically just how it works.The flu virus evolves a new shell almost every season, exactly because the immune system reacts on its outer envelope.
'They' have no system to switch between different env genes, as you'd need a lot of overhead for that.
Having a lot of mutations between each generation and letting basic evolution take its course works much more efficiently.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846417</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29852665</id>
	<title>DNA and RNA?</title>
	<author>Anonymous</author>
	<datestamp>1256298720000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>&gt;<nobr> <wbr></nobr>... but that contain no influenza RNA genetic material.<br>&gt;<nobr> <wbr></nobr>... more quickly than current methods, using just the DNA of the virus.</p><p>Most viruses contain no DNA at all, just RNA...and according to your own story, neither process uses any "real" viral material at all...just a synthesized protein coat!</p></htmltext>
<tokenext>&gt; ... but that contain no influenza RNA genetic material. &gt; ... more quickly than current methods , using just the DNA of the virus.Most viruses contain no DNA at all , just RNA...and according to your own story , neither process uses any " real " viral material at all...just a synthesized protein coat !</tokentext>
<sentencetext>&gt; ... but that contain no influenza RNA genetic material.&gt; ... more quickly than current methods, using just the DNA of the virus.Most viruses contain no DNA at all, just RNA...and according to your own story, neither process uses any "real" viral material at all...just a synthesized protein coat!</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846693</id>
	<title>Re:I'm surprisde no one's done this before</title>
	<author>ColdWetDog</author>
	<datestamp>1256316300000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>3</modscore>
	<htmltext><blockquote><div><p>since antibodies react to proteins or other structures and not the RNA/DNA. Maybe profits on vaccines aren't really there?</p></div>
</blockquote><p>

Or, alternatively, they've been trying for a long time without success.  FTFA:</p><blockquote><div><p>VLPs have been an around-the-corner promise for over 20 years. But they've now reached a stage at which even disinterested observers believe, as Columbia University virologist Vincent Racaniello put it, that VLP vaccines "really seem to be coming into their own."</p></div> </blockquote><p>

But don't roll up your sleeve just yet.  Sounds a lot like holographic storage, Duke Nukem Forever, better batteries, flying cars, jet packs, sensible women.</p></div>
	</htmltext>
<tokenext>since antibodies react to proteins or other structures and not the RNA/DNA .
Maybe profits on vaccines are n't really there ?
Or , alternatively , they 've been trying for a long time without success .
FTFA : VLPs have been an around-the-corner promise for over 20 years .
But they 've now reached a stage at which even disinterested observers believe , as Columbia University virologist Vincent Racaniello put it , that VLP vaccines " really seem to be coming into their own .
" But do n't roll up your sleeve just yet .
Sounds a lot like holographic storage , Duke Nukem Forever , better batteries , flying cars , jet packs , sensible women .</tokentext>
<sentencetext>since antibodies react to proteins or other structures and not the RNA/DNA.
Maybe profits on vaccines aren't really there?
Or, alternatively, they've been trying for a long time without success.
FTFA:VLPs have been an around-the-corner promise for over 20 years.
But they've now reached a stage at which even disinterested observers believe, as Columbia University virologist Vincent Racaniello put it, that VLP vaccines "really seem to be coming into their own.
" 

But don't roll up your sleeve just yet.
Sounds a lot like holographic storage, Duke Nukem Forever, better batteries, flying cars, jet packs, sensible women.
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846413</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846525</id>
	<title>Umbrella?</title>
	<author>SnarfQuest</author>
	<datestamp>1256315280000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>Is this how the Umbrella corp got their start in creating a Zombie virus?</p><p>Hopefully these researchers have created a decent underground lab, with flooded rooms, insane computers, dogs ready to be zombiefied, lots of corridors, exotic weapons with ammo dropped in numerous random places, and other useful stuff. If I was building a virus lab, I'd definately need to have all this available in case someone needs to sneak in and blow it up.</p></htmltext>
<tokenext>Is this how the Umbrella corp got their start in creating a Zombie virus ? Hopefully these researchers have created a decent underground lab , with flooded rooms , insane computers , dogs ready to be zombiefied , lots of corridors , exotic weapons with ammo dropped in numerous random places , and other useful stuff .
If I was building a virus lab , I 'd definately need to have all this available in case someone needs to sneak in and blow it up .</tokentext>
<sentencetext>Is this how the Umbrella corp got their start in creating a Zombie virus?Hopefully these researchers have created a decent underground lab, with flooded rooms, insane computers, dogs ready to be zombiefied, lots of corridors, exotic weapons with ammo dropped in numerous random places, and other useful stuff.
If I was building a virus lab, I'd definately need to have all this available in case someone needs to sneak in and blow it up.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29851419</id>
	<title>Release under the GPL</title>
	<author>ldj</author>
	<datestamp>1256291340000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>If they release the particles under the GPL, would that square their viral properties or just double them?</htmltext>
<tokenext>If they release the particles under the GPL , would that square their viral properties or just double them ?</tokentext>
<sentencetext>If they release the particles under the GPL, would that square their viral properties or just double them?</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29847719</id>
	<title>Re:no flu vaccines for me thanks</title>
	<author>ChromeAeonium</author>
	<datestamp>1256320980000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>2</modscore>
	<htmltext><p>I could have modded you down, but since there is no -1 Wrong moderation, I decided to correct you instead.  When you use a vaccine, you ARE relying on your immune system.  All vaccines do is help create an immune response in a manner usually safer than the disease.  I say usually because vaccines aren't supposed to eliminate all the risk.  That's impossible; all reward has risk.  Would you rather have, for example, a 1/50,000 chance of getting hurt by the flu, or a 1/1,000,000 chance of getting hurt by the vaccine.  Those aren't actual statistics, but you get the idea.  It is true that people are hurt by vaccines, and yes, they sometimes die from the vaccine, but the point is that they're safer than not getting vaccinated.  I don't know why there has to be this false dichotomy that because a vaccine is not absolutely perfect that it is dangerous. I mean, it would be like claiming that you shouldn't wear a seat belt or use airbags because people have been hurt by those things.  They save many, many more than they harm.  It is not about eliminating danger, it is about mitigating the danger to lower levels.  It is just asinine and illogical to say that because vaccines aren't fairy dust panaceas you shouldn't get one.  I hope people realize that the vast, vast majority of this anti-vaccine nonsense has its <a href="http://en.wikipedia.org/wiki/File:The\_cow\_pock.jpg" title="wikipedia.org">cultural roots</a> [wikipedia.org] in anti-scientific fear-mongers (lookin' at you, Wakefield), not actual fact.</p></htmltext>
<tokenext>I could have modded you down , but since there is no -1 Wrong moderation , I decided to correct you instead .
When you use a vaccine , you ARE relying on your immune system .
All vaccines do is help create an immune response in a manner usually safer than the disease .
I say usually because vaccines are n't supposed to eliminate all the risk .
That 's impossible ; all reward has risk .
Would you rather have , for example , a 1/50,000 chance of getting hurt by the flu , or a 1/1,000,000 chance of getting hurt by the vaccine .
Those are n't actual statistics , but you get the idea .
It is true that people are hurt by vaccines , and yes , they sometimes die from the vaccine , but the point is that they 're safer than not getting vaccinated .
I do n't know why there has to be this false dichotomy that because a vaccine is not absolutely perfect that it is dangerous .
I mean , it would be like claiming that you should n't wear a seat belt or use airbags because people have been hurt by those things .
They save many , many more than they harm .
It is not about eliminating danger , it is about mitigating the danger to lower levels .
It is just asinine and illogical to say that because vaccines are n't fairy dust panaceas you should n't get one .
I hope people realize that the vast , vast majority of this anti-vaccine nonsense has its cultural roots [ wikipedia.org ] in anti-scientific fear-mongers ( lookin ' at you , Wakefield ) , not actual fact .</tokentext>
<sentencetext>I could have modded you down, but since there is no -1 Wrong moderation, I decided to correct you instead.
When you use a vaccine, you ARE relying on your immune system.
All vaccines do is help create an immune response in a manner usually safer than the disease.
I say usually because vaccines aren't supposed to eliminate all the risk.
That's impossible; all reward has risk.
Would you rather have, for example, a 1/50,000 chance of getting hurt by the flu, or a 1/1,000,000 chance of getting hurt by the vaccine.
Those aren't actual statistics, but you get the idea.
It is true that people are hurt by vaccines, and yes, they sometimes die from the vaccine, but the point is that they're safer than not getting vaccinated.
I don't know why there has to be this false dichotomy that because a vaccine is not absolutely perfect that it is dangerous.
I mean, it would be like claiming that you shouldn't wear a seat belt or use airbags because people have been hurt by those things.
They save many, many more than they harm.
It is not about eliminating danger, it is about mitigating the danger to lower levels.
It is just asinine and illogical to say that because vaccines aren't fairy dust panaceas you shouldn't get one.
I hope people realize that the vast, vast majority of this anti-vaccine nonsense has its cultural roots [wikipedia.org] in anti-scientific fear-mongers (lookin' at you, Wakefield), not actual fact.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846743</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846777</id>
	<title>Virus-like Vaccine</title>
	<author>Anonymous</author>
	<datestamp>1256316720000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>C'mon folks, did nobody watch I Am Legend?</htmltext>
<tokenext>C'mon folks , did nobody watch I Am Legend ?</tokentext>
<sentencetext>C'mon folks, did nobody watch I Am Legend?</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846413</id>
	<title>I'm surprisde no one's done this before</title>
	<author>the\_humeister</author>
	<datestamp>1256314740000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>since antibodies react to proteins or other structures and not the RNA/DNA. Maybe profits on vaccines aren't really there?</p></htmltext>
<tokenext>since antibodies react to proteins or other structures and not the RNA/DNA .
Maybe profits on vaccines are n't really there ?</tokentext>
<sentencetext>since antibodies react to proteins or other structures and not the RNA/DNA.
Maybe profits on vaccines aren't really there?</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846553</id>
	<title>Re:Flu !DNA</title>
	<author>Anonymous</author>
	<datestamp>1256315460000</datestamp>
	<modclass>Informativ</modclass>
	<modscore>2</modscore>
	<htmltext><p>Although influenza is an RNA virus, researchers are probably generating a cDNA library of the flu structural proteins and using these DNA templates to transfect their cellular expression systems, resulting in the production of the virus-like particles. This may be the source of confusion in the summary above.</p></htmltext>
<tokenext>Although influenza is an RNA virus , researchers are probably generating a cDNA library of the flu structural proteins and using these DNA templates to transfect their cellular expression systems , resulting in the production of the virus-like particles .
This may be the source of confusion in the summary above .</tokentext>
<sentencetext>Although influenza is an RNA virus, researchers are probably generating a cDNA library of the flu structural proteins and using these DNA templates to transfect their cellular expression systems, resulting in the production of the virus-like particles.
This may be the source of confusion in the summary above.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846387</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29847451</id>
	<title>Patents?</title>
	<author>etenil</author>
	<datestamp>1256319900000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>How many patents on this thing again? I guess the developping countries arent' gonna get it before a while without paying these lab's taxes.</htmltext>
<tokenext>How many patents on this thing again ?
I guess the developping countries arent ' gon na get it before a while without paying these lab 's taxes .</tokentext>
<sentencetext>How many patents on this thing again?
I guess the developping countries arent' gonna get it before a while without paying these lab's taxes.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846743</id>
	<title>no flu vaccines for me thanks</title>
	<author>Anonymous</author>
	<datestamp>1256316480000</datestamp>
	<modclass>Offtopic</modclass>
	<modscore>-1</modscore>
	<htmltext>i heard of too <i>bad</i> <b>bad</b> side effects including fatal side effects, i will rely on my immune system.</htmltext>
<tokenext>i heard of too bad bad side effects including fatal side effects , i will rely on my immune system .</tokentext>
<sentencetext>i heard of too bad bad side effects including fatal side effects, i will rely on my immune system.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29850701</id>
	<title>I for one welcome..</title>
	<author>Anonymous</author>
	<datestamp>1256288640000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>...our zombie overlords. It has begun!</p></htmltext>
<tokenext>...our zombie overlords .
It has begun !</tokentext>
<sentencetext>...our zombie overlords.
It has begun!</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29849395</id>
	<title>Re:no flu vaccines for me thanks</title>
	<author>nietsch</author>
	<datestamp>1256326800000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>Sure, after all it is just a different flu. However, the statistics who dies from it suggest that a strong immune system is an extra risk, the deaths are not in the age categories you would expect with a normal flu.<br>But your decision seems to be based on scary stories, and fear is not a good advisor in general and neither is stubbornness. Your call, Darwin may take care of you...</p></htmltext>
<tokenext>Sure , after all it is just a different flu .
However , the statistics who dies from it suggest that a strong immune system is an extra risk , the deaths are not in the age categories you would expect with a normal flu.But your decision seems to be based on scary stories , and fear is not a good advisor in general and neither is stubbornness .
Your call , Darwin may take care of you.. .</tokentext>
<sentencetext>Sure, after all it is just a different flu.
However, the statistics who dies from it suggest that a strong immune system is an extra risk, the deaths are not in the age categories you would expect with a normal flu.But your decision seems to be based on scary stories, and fear is not a good advisor in general and neither is stubbornness.
Your call, Darwin may take care of you...</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846743</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846937</id>
	<title>Re:Flu !DNA</title>
	<author>Jon-1</author>
	<datestamp>1256317500000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>While you're correct in your analysis of the statement, you're incorrect in regards to the technology.  Yes, flu is an RNA virus but the manipulations of the genes that are expressed on the VLP - is all done with DNA.  I'm guessing they clone the gene into their expression platform and the cell lines do all the work to put it together.</p><p>Now the big challenge is to prevent the patient from developing anit-vector immunity so that they can use the VLP delivery system again against different targets.</p></htmltext>
<tokenext>While you 're correct in your analysis of the statement , you 're incorrect in regards to the technology .
Yes , flu is an RNA virus but the manipulations of the genes that are expressed on the VLP - is all done with DNA .
I 'm guessing they clone the gene into their expression platform and the cell lines do all the work to put it together.Now the big challenge is to prevent the patient from developing anit-vector immunity so that they can use the VLP delivery system again against different targets .</tokentext>
<sentencetext>While you're correct in your analysis of the statement, you're incorrect in regards to the technology.
Yes, flu is an RNA virus but the manipulations of the genes that are expressed on the VLP - is all done with DNA.
I'm guessing they clone the gene into their expression platform and the cell lines do all the work to put it together.Now the big challenge is to prevent the patient from developing anit-vector immunity so that they can use the VLP delivery system again against different targets.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846387</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846459</id>
	<title>Bonk bonk on the head</title>
	<author>Tablizer</author>
	<datestamp>1256314980000</datestamp>
	<modclass>Funny</modclass>
	<modscore>3</modscore>
	<htmltext><p>I explained traditional vaccines like this to my kids: "What they do is get some of bad viruses, we'll call them little monsters. So they clone these monsters (kids learn what cloning is from cartoons) and then bonk them in the head to make them all dizzy. Then they send these dizzy monsters into the village, which is your body. The villagers see the monsters and beat the Cheerios out of them, and then kick them out of the city. They also learn to recognize the monsters. So when the real monsters come, the ones that are not dizzy, the villagers know how to recognize them because they look just like the dizzy ones. That's how they know to find the monsters and kick them out."</p><p>Kid: "But daddy, why don't they just put up a Wanted poster?"</p><p>Me: "Uh, go ask your mom."<br>
&nbsp; &nbsp; &nbsp;</p></htmltext>
<tokenext>I explained traditional vaccines like this to my kids : " What they do is get some of bad viruses , we 'll call them little monsters .
So they clone these monsters ( kids learn what cloning is from cartoons ) and then bonk them in the head to make them all dizzy .
Then they send these dizzy monsters into the village , which is your body .
The villagers see the monsters and beat the Cheerios out of them , and then kick them out of the city .
They also learn to recognize the monsters .
So when the real monsters come , the ones that are not dizzy , the villagers know how to recognize them because they look just like the dizzy ones .
That 's how they know to find the monsters and kick them out .
" Kid : " But daddy , why do n't they just put up a Wanted poster ?
" Me : " Uh , go ask your mom .
"      </tokentext>
<sentencetext>I explained traditional vaccines like this to my kids: "What they do is get some of bad viruses, we'll call them little monsters.
So they clone these monsters (kids learn what cloning is from cartoons) and then bonk them in the head to make them all dizzy.
Then they send these dizzy monsters into the village, which is your body.
The villagers see the monsters and beat the Cheerios out of them, and then kick them out of the city.
They also learn to recognize the monsters.
So when the real monsters come, the ones that are not dizzy, the villagers know how to recognize them because they look just like the dizzy ones.
That's how they know to find the monsters and kick them out.
"Kid: "But daddy, why don't they just put up a Wanted poster?
"Me: "Uh, go ask your mom.
"
     </sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29847157</id>
	<title>EC101</title>
	<author>Anonymous</author>
	<datestamp>1256318580000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><a href="http://www.hss.caltech.edu/~camerer/Ec101/JudgementUncertainty.pdf" title="caltech.edu">http://www.hss.caltech.edu/~camerer/Ec101/JudgementUncertainty.pdf</a> [caltech.edu]
<br> <br>
Tversky, A. &amp; Kahneman, D. (1974). Judgment under uncertainty: Heuristics and biases. Science, 185, 1124-1130
<br> <br>
CC.</htmltext>
<tokenext>http : //www.hss.caltech.edu/ ~ camerer/Ec101/JudgementUncertainty.pdf [ caltech.edu ] Tversky , A .
&amp; Kahneman , D. ( 1974 ) . Judgment under uncertainty : Heuristics and biases .
Science , 185 , 1124-1130 CC .</tokentext>
<sentencetext>http://www.hss.caltech.edu/~camerer/Ec101/JudgementUncertainty.pdf [caltech.edu]
 
Tversky, A.
&amp; Kahneman, D. (1974). Judgment under uncertainty: Heuristics and biases.
Science, 185, 1124-1130
 
CC.</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29858101</id>
	<title>Re:Flu !DNA</title>
	<author>Anonymous</author>
	<datestamp>1256410740000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p><div class="quote"><blockquote><div><p>Providing they pass safety muster, both techniques should be able to produce an influenza vaccine more quickly than current methods, using just the DNA of the virus.</p></div></blockquote><p>Sorry to nitpick, but influenza is an RNA virus, not a DNA virus.</p><p>I have no clue if this makes a difference in how quickly a vaccine could be made using this technique, but I just needed to get the "Friday Pedantry" out of the way.</p></div><p>Watch the truth about H1N! Here</p><p>http://www.youtube.com/watch?v=3Up2LPtZAbg&amp;feature=video\_responseInteresting</p></div>
	</htmltext>
<tokenext>Providing they pass safety muster , both techniques should be able to produce an influenza vaccine more quickly than current methods , using just the DNA of the virus.Sorry to nitpick , but influenza is an RNA virus , not a DNA virus.I have no clue if this makes a difference in how quickly a vaccine could be made using this technique , but I just needed to get the " Friday Pedantry " out of the way.Watch the truth about H1N !
Herehttp : //www.youtube.com/watch ? v = 3Up2LPtZAbg&amp;feature = video \ _responseInteresting</tokentext>
<sentencetext>Providing they pass safety muster, both techniques should be able to produce an influenza vaccine more quickly than current methods, using just the DNA of the virus.Sorry to nitpick, but influenza is an RNA virus, not a DNA virus.I have no clue if this makes a difference in how quickly a vaccine could be made using this technique, but I just needed to get the "Friday Pedantry" out of the way.Watch the truth about H1N!
Herehttp://www.youtube.com/watch?v=3Up2LPtZAbg&amp;feature=video\_responseInteresting
	</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846387</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29847269</id>
	<title>They're not the only ones...</title>
	<author>guzziguy</author>
	<datestamp>1256319120000</datestamp>
	<modclass>Informativ</modclass>
	<modscore>2</modscore>
	<htmltext>Antigen Express is working on a synthetic flu vaccine that doesn't use tobacco or caterpillars:<p>

<a href="http://www.masshightech.com/blog/2009/09/25/antigen-express-synthetic-h1n1-flu-vaccine-in-the-works/" title="masshightech.com" rel="nofollow">http://www.masshightech.com/blog/2009/09/25/antigen-express-synthetic-h1n1-flu-vaccine-in-the-works/</a> [masshightech.com]</p></htmltext>
<tokenext>Antigen Express is working on a synthetic flu vaccine that does n't use tobacco or caterpillars : http : //www.masshightech.com/blog/2009/09/25/antigen-express-synthetic-h1n1-flu-vaccine-in-the-works/ [ masshightech.com ]</tokentext>
<sentencetext>Antigen Express is working on a synthetic flu vaccine that doesn't use tobacco or caterpillars:

http://www.masshightech.com/blog/2009/09/25/antigen-express-synthetic-h1n1-flu-vaccine-in-the-works/ [masshightech.com]</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846387</id>
	<title>Flu !DNA</title>
	<author>Red Flayer</author>
	<datestamp>1256314620000</datestamp>
	<modclass>Insightful</modclass>
	<modscore>3</modscore>
	<htmltext><blockquote><div><p>Providing they pass safety muster, both techniques should be able to produce an influenza vaccine more quickly than current methods, using just the DNA of the virus.</p></div></blockquote><p>Sorry to nitpick, but influenza is an RNA virus, not a DNA virus.<br> <br>I have no clue if this makes a difference in how quickly a vaccine could be made using this technique, but I just needed to get the "Friday Pedantry" out of the way.</p></div>
	</htmltext>
<tokenext>Providing they pass safety muster , both techniques should be able to produce an influenza vaccine more quickly than current methods , using just the DNA of the virus.Sorry to nitpick , but influenza is an RNA virus , not a DNA virus .
I have no clue if this makes a difference in how quickly a vaccine could be made using this technique , but I just needed to get the " Friday Pedantry " out of the way .</tokentext>
<sentencetext>Providing they pass safety muster, both techniques should be able to produce an influenza vaccine more quickly than current methods, using just the DNA of the virus.Sorry to nitpick, but influenza is an RNA virus, not a DNA virus.
I have no clue if this makes a difference in how quickly a vaccine could be made using this technique, but I just needed to get the "Friday Pedantry" out of the way.
	</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29849343</id>
	<title>Re:Typical big media...</title>
	<author>Convector</author>
	<datestamp>1256326560000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>The goal is to make a Very Hungry Caterpillar.</htmltext>
<tokenext>The goal is to make a Very Hungry Caterpillar .</tokentext>
<sentencetext>The goal is to make a Very Hungry Caterpillar.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846361</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846831</id>
	<title>Good idea</title>
	<author>Anonymous</author>
	<datestamp>1256316900000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext><p>That's so.... obvious! Why dont they put inside of those shells some "good" rna? you know, a rna to make us stronger and smarter. Then  the apocalipse can happen, finally!</p></htmltext>
<tokenext>That 's so.... obvious ! Why dont they put inside of those shells some " good " rna ?
you know , a rna to make us stronger and smarter .
Then the apocalipse can happen , finally !</tokentext>
<sentencetext>That's so.... obvious! Why dont they put inside of those shells some "good" rna?
you know, a rna to make us stronger and smarter.
Then  the apocalipse can happen, finally!</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29849259</id>
	<title>Re:Bonk bonk on the head</title>
	<author>TheTyrannyOfForcedRe</author>
	<datestamp>1256326320000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>I'm dying to hear your explanation of the "birds and the bees..."</htmltext>
<tokenext>I 'm dying to hear your explanation of the " birds and the bees... "</tokentext>
<sentencetext>I'm dying to hear your explanation of the "birds and the bees..."</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846459</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29848157</id>
	<title>Mod parent up Funny.</title>
	<author>mail2345</author>
	<datestamp>1256322420000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>It's a joke. I guess it looks like a troll when abbreviated, but really, you should read the entire comment before modding.</htmltext>
<tokenext>It 's a joke .
I guess it looks like a troll when abbreviated , but really , you should read the entire comment before modding .</tokentext>
<sentencetext>It's a joke.
I guess it looks like a troll when abbreviated, but really, you should read the entire comment before modding.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846361</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846361</id>
	<title>Typical big media...</title>
	<author>Anonymous</author>
	<datestamp>1256314500000</datestamp>
	<modclass>Funny</modclass>
	<modscore>0</modscore>
	<htmltext><p>It's just like big media, which Slashdot is part of, to ignore the REAL story in the story</p><p><div class="quote"><p>"immortalized" cells taken from caterpillars.</p></div><p>You guys are running around producing Immortal caterpillars and noone let me know? Bastards!</p></div>
	</htmltext>
<tokenext>It 's just like big media , which Slashdot is part of , to ignore the REAL story in the story " immortalized " cells taken from caterpillars.You guys are running around producing Immortal caterpillars and noone let me know ?
Bastards !</tokentext>
<sentencetext>It's just like big media, which Slashdot is part of, to ignore the REAL story in the story"immortalized" cells taken from caterpillars.You guys are running around producing Immortal caterpillars and noone let me know?
Bastards!
	</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846465</id>
	<title>Re:Flu !DNA</title>
	<author>sanosuke001</author>
	<datestamp>1256315040000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>Don't feel bad; I came here to say the exact same thing.</htmltext>
<tokenext>Do n't feel bad ; I came here to say the exact same thing .</tokentext>
<sentencetext>Don't feel bad; I came here to say the exact same thing.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846387</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846405</id>
	<title>A new method of vaccine delivery?</title>
	<author>Tsar</author>
	<datestamp>1256314680000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p><div class="quote"><p>A company called Medicago grows its VLPs in transgenic tobacco plants...</p></div><p>So tomorrow's vaccines can be administered by cigarette?</p></div>
	</htmltext>
<tokenext>A company called Medicago grows its VLPs in transgenic tobacco plants...So tomorrow 's vaccines can be administered by cigarette ?</tokentext>
<sentencetext>A company called Medicago grows its VLPs in transgenic tobacco plants...So tomorrow's vaccines can be administered by cigarette?
	</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29847187</id>
	<title>Re:Bonk bonk on the head</title>
	<author>mikael</author>
	<datestamp>1256318760000</datestamp>
	<modclass>Informativ</modclass>
	<modscore>2</modscore>
	<htmltext><p>The nasal spray version of the vaccine does contain live virus, but "attenuated" so that it can only reproduce in the lining of the nose.</p></htmltext>
<tokenext>The nasal spray version of the vaccine does contain live virus , but " attenuated " so that it can only reproduce in the lining of the nose .</tokentext>
<sentencetext>The nasal spray version of the vaccine does contain live virus, but "attenuated" so that it can only reproduce in the lining of the nose.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846591</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846591</id>
	<title>Re:Bonk bonk on the head</title>
	<author>geekoid</author>
	<datestamp>1256315700000</datestamp>
	<modclass>Interestin</modclass>
	<modscore>2</modscore>
	<htmltext><p>Funnny, but what the kid asks uis actually closer to how a vaccine works.</p><p>A dizzy monster might recover and go rampaging through the village. The flu vaccine is not a live virrus and as such it is like putting a wanted poster up.</p></htmltext>
<tokenext>Funnny , but what the kid asks uis actually closer to how a vaccine works.A dizzy monster might recover and go rampaging through the village .
The flu vaccine is not a live virrus and as such it is like putting a wanted poster up .</tokentext>
<sentencetext>Funnny, but what the kid asks uis actually closer to how a vaccine works.A dizzy monster might recover and go rampaging through the village.
The flu vaccine is not a live virrus and as such it is like putting a wanted poster up.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846459</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29847681</id>
	<title>Re:Bonk bonk on the head</title>
	<author>Schickeneder</author>
	<datestamp>1256320800000</datestamp>
	<modclass>Interestin</modclass>
	<modscore>2</modscore>
	<htmltext><p>They do put up wanted posters.  They're known as major histocompatibility complexes!</p><p><a href="http://en.wikipedia.org/wiki/Major\_histocompatibility\_complex" title="wikipedia.org" rel="nofollow">http://en.wikipedia.org/wiki/Major\_histocompatibility\_complex</a> [wikipedia.org]</p></htmltext>
<tokenext>They do put up wanted posters .
They 're known as major histocompatibility complexes ! http : //en.wikipedia.org/wiki/Major \ _histocompatibility \ _complex [ wikipedia.org ]</tokentext>
<sentencetext>They do put up wanted posters.
They're known as major histocompatibility complexes!http://en.wikipedia.org/wiki/Major\_histocompatibility\_complex [wikipedia.org]</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846459</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846749</id>
	<title>Re:Bonk bonk on the head</title>
	<author>Aladrin</author>
	<datestamp>1256316540000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>The flu vaccine can cause the flu.  A wanted poster cannot rob a house.</p></htmltext>
<tokenext>The flu vaccine can cause the flu .
A wanted poster can not rob a house .</tokentext>
<sentencetext>The flu vaccine can cause the flu.
A wanted poster cannot rob a house.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846591</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29849331</id>
	<title>No?</title>
	<author>nietsch</author>
	<datestamp>1256326500000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext><p>No, i did not watch this 'I am legend' thing you talk about. What is it, a painting or something?</p></htmltext>
<tokenext>No , i did not watch this 'I am legend ' thing you talk about .
What is it , a painting or something ?</tokentext>
<sentencetext>No, i did not watch this 'I am legend' thing you talk about.
What is it, a painting or something?</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846777</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29847881</id>
	<title>Where's the WCPGW? tag?</title>
	<author>mujadaddy</author>
	<datestamp>1256321520000</datestamp>
	<modclass>None</modclass>
	<modscore>1</modscore>
	<htmltext>Where's the "What could possibly go wrong?" tag?</htmltext>
<tokenext>Where 's the " What could possibly go wrong ?
" tag ?</tokentext>
<sentencetext>Where's the "What could possibly go wrong?
" tag?</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846417</id>
	<title>I wonder...</title>
	<author>ShadowXOmega</author>
	<datestamp>1256314740000</datestamp>
	<modclass>None</modclass>
	<modscore>0</modscore>
	<htmltext>Im not a Genetist (INAG), so my question may sound dull or obvious... <br> <br>
but, the virus dna in the vaccine really dont have any function?... <br>
<br>
i think the shell only aproach may trigger a immediate response (much like an allergy), but im not sure about the long term protection...
<br>
<br>cant a virus use 2 or more diferent kinds of shells?, that is, same virus(or very similar) with widly diferent protein shells?</htmltext>
<tokenext>Im not a Genetist ( INAG ) , so my question may sound dull or obvious.. . but , the virus dna in the vaccine really dont have any function ? .. .
i think the shell only aproach may trigger a immediate response ( much like an allergy ) , but im not sure about the long term protection.. . cant a virus use 2 or more diferent kinds of shells ? , that is , same virus ( or very similar ) with widly diferent protein shells ?</tokentext>
<sentencetext>Im not a Genetist (INAG), so my question may sound dull or obvious...  
but, the virus dna in the vaccine really dont have any function?...
i think the shell only aproach may trigger a immediate response (much like an allergy), but im not sure about the long term protection...

cant a virus use 2 or more diferent kinds of shells?, that is, same virus(or very similar) with widly diferent protein shells?</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29847151</id>
	<title>Re:no flu vaccines for me thanks</title>
	<author>rrohbeck</author>
	<datestamp>1256318580000</datestamp>
	<modclass>Informativ</modclass>
	<modscore>2</modscore>
	<htmltext><p>Serious side effects from vaccination are on the order of one in a million or less, serious disease from the flu is on the order of one in thousand or more.</p></htmltext>
<tokenext>Serious side effects from vaccination are on the order of one in a million or less , serious disease from the flu is on the order of one in thousand or more .</tokentext>
<sentencetext>Serious side effects from vaccination are on the order of one in a million or less, serious disease from the flu is on the order of one in thousand or more.</sentencetext>
	<parent>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846743</parent>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29846391</id>
	<title>Goatse!</title>
	<author>Anonymous</author>
	<datestamp>1256314620000</datestamp>
	<modclass>Offtopic</modclass>
	<modscore>-1</modscore>
	<htmltext><p>Dr. Goatse probably has lotsa virii, yo!</p></htmltext>
<tokenext>Dr. Goatse probably has lotsa virii , yo !</tokentext>
<sentencetext>Dr. Goatse probably has lotsa virii, yo!</sentencetext>
</comment>
<comment>
	<id>http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29847857</id>
	<title>Such a shame</title>
	<author>TrumpetPower!</author>
	<datestamp>1256321460000</datestamp>
	<modclass>Offtopic</modclass>
	<modscore>-1</modscore>
	<htmltext><p>While I&rsquo;m sure this is great news for all those Commie pinko atheist libruls out there, the Truth of the matter is that vaccines are the leading cause of Down&rsquo;s Syndrome, abortions, homosexuality, and alien anal probes, so you can take that needle and shove it where the sun don&rsquo;t shine.</p><p>

&lt;/sarcasm mode="depressingly-semi-serious"&gt;

</p><p>Cheers,</p><p>b&amp;</p></htmltext>
<tokenext>While I    m sure this is great news for all those Commie pinko atheist libruls out there , the Truth of the matter is that vaccines are the leading cause of Down    s Syndrome , abortions , homosexuality , and alien anal probes , so you can take that needle and shove it where the sun don    t shine .
Cheers,b&amp;</tokentext>
<sentencetext>While I’m sure this is great news for all those Commie pinko atheist libruls out there, the Truth of the matter is that vaccines are the leading cause of Down’s Syndrome, abortions, homosexuality, and alien anal probes, so you can take that needle and shove it where the sun don’t shine.
Cheers,b&amp;</sentencetext>
</comment>
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--http://www.semanticweb.org/ontologies/ConversationInstances.owl#comment09_10_23_1333228.29847187
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