Application: Protein Alignment
Goal: Determine how two
protein sequences are
related
Proteins are strings of amino
acids
There are 20 amino acids
DNA is basically a machine
for making proteins
An amino acid within a
protein is often called a
residue
Mutations can
Replace one amino acid by
another
Delete an amino acid
Add an amino acid
What is the optimal
alignment of two protein
sequences?
There can be substitutions
There can be gaps
CS409 - Spring 2000
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