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Robert De Niro plays a therapist who is an obsessive-compulsive agoraphobic and hasn't left his apartment in six years. In order to continue giving therapy without leaving his home he gives it over the internet. From afar, he falls in love with a female police dispatcher who works directly across the street. But when De Niro finds out the woman has been targeted for murder, he and his agoraphobic roommate are forced to leave the apartment (after six years) to save her life.
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